KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
     05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
       K24862  gp46; HTLV envelope surface glycoprotein gp46
       K24863  gp21; HTLV envelope transmembrane protein gp21
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K06724  NRP1, CD304; neuropilin 1
       K04377  MYC; Myc proto-oncogene protein
       K08874  TRRAP; transformation/transcription domain-associated protein
       K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
       K10151  CCND2; G1/S-specific cyclin-D2
       K23068  p30II; HTLV-1 accessory protein p30II
       K05718  ITGAL, CD11a; integrin alpha L
       K06464  ITGB2, CD18; integrin beta 2
       K06490  ICAM1, CD54; intercellular adhesion molecule 1
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K06454  CD4; T-cell surface glycoprotein CD4
       K19259  env; Deltaretrovirus envelope glycoprotein gp62
       K25051  MA; HTLV-1 matrix protein
       K06271  TLN; talin
       K23069  p12I; HTLV-1 accessory protein p12I
       K23018  rex; HTLV-1 rex polyprotein
       K15304  RANBP3; Ran-binding protein 3
       K07936  RAN; GTP-binding nuclear protein Ran
       K14290  XPO1, CRM1; exportin-1
       K08057  CALR; calreticulin
       K08054  CANX; calnexin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K05429  IL2; interleukin 2
       K06751  MHC1; MHC class I antigen
       K08055  B2M; beta-2-microglobulin
       K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
       K23070  p13; HTLV-1 accessory protein p13
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05770  TSPO, BZRP; translocator protein
       K15305  VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
       K15306  RANBP1; Ran-binding protein 1
       K21857  tax; Deltaretrovirus protein Tax-1
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K03348  APC1, ANAPC1; anaphase-promoting complex subunit 1
       K03349  APC2, ANAPC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4, ANAPC4; anaphase-promoting complex subunit 4
       K03352  APC5, ANAPC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7, ANAPC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03357  APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11, ANAPC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13, ANAPC13; anaphase-promoting complex subunit 13
       K25228  APC15, ANAPC15; anaphase-promoting complex subunit 15
       K25229  APC16, ANAPC16; anaphase-promoting complex subunit 16
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K06635  PTTG; securin
       K02365  ESP1; separase [EC:3.4.22.49]
       K21770  CCNB2; G2/mitotic-specific cyclin-B2
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K04503  CCND1; G1/S-specific cyclin-D1
       K10152  CCND3; G1/S-specific cyclin-D3
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06627  CCNA; cyclin-A
       K06626  CCNE; G1/S-specific cyclin-E1
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K02216  CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
       K06641  CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K12076  DLG1; disks large protein 1
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K01397  MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
       K23071  HBZ; HTLV-1 basic zipper factor
       K04386  IL1R1, CD121a; interleukin 1 receptor type I
       K04387  IL1R2, CD121b; interleukin 1 receptor type II
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
       K06451  CD3E; T-cell surface glycoprotein CD3 epsilon chain
       K06452  CD3G; T-cell surface glycoprotein CD3 gamma chain
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K15307  GPS2; G protein pathway suppressor 2
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K05151  TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K15308  TTP; tristetraprolin
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05433  IL15; interleukin 15
       K05074  IL15RA, CD215; interleukin 15 receptor alpha
       K05405  IL6; interleukin 6
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2; mothers against decapentaplegic homolog 2
       K23605  SMAD3; mothers against decapentaplegic homolog 3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K08065  NFYB, HAP3; nuclear transcription Y subunit beta
       K06752  MHC2; MHC class II antigen
       K04378  SRF; serum response factor
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K09438  SPI1; transcription factor PU.1
       K02678  ETS1, pnt; C-ets-1
       K21932  ETS2; C-ets-2
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K04379  FOS; proto-oncogene protein c-fos
       K09203  EGR1; early growth response protein 1
       K04502  FOSL1; fos-like antigen 1
       K12496  EGR2; early growth response protein 2
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K15309  CRTC1, TORC1; CREB-regulated transcription coactivator 1
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16334  CRTC3, TORC3; CREB-regulated transcription coactivator 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K09063  TCF3, E2A; transcription factor E2-alpha
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K02159  BAX; apoptosis regulator BAX
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K09341  MSX; homeobox protein MSX
       K25052  CA; HTLV-1 capsid protein
       K25053  NC; HTLV-1 nucleocapsid protein
       K25054  PR; HTLV-1 protease [EC:3.4.23.-]
       K25055  RT; HTLV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.4]
       K25056  IN; HTLV-1 integrase
     05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
     05171 Coronavirus disease - COVID-19 [PATH:ko05171]
     05164 Influenza A [PATH:ko05164]
     05162 Measles [PATH:ko05162]
     05168 Herpes simplex virus 1 infection [PATH:ko05168]
     05163 Human cytomegalovirus infection [PATH:ko05163]
     05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
       K21649  ORF4; KSHV complement control protein
       K03990  C3; complement component 3
       K05401  TLR3, CD283; toll-like receptor 3
       K05842  TRIF; toll-like receptor adapter molecule 1
       K03174  TRAF3; TNF receptor-associated factor 3
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K09447  IRF7; interferon regulatory factor 7
       K21650  KIE1, ORF50; KSHV transcription activator ORF50
       K21859  KIE2, ORF45; KSHV transcription activator ORF45
       K21652  vIRF3; KSHV interferon regulatory factor-like protein 3
       K05414  IFNA; interferon alpha
       K05411  IRF3; interferon regulatory factor 3
       K21653  vIRF1, K9; KSHV interferon regulatory factor-like protein 1
       K21654  vIRF2, K11; KSHV interferon regulatory factor-like protein 2
       K21655  K8; KSHV E3 SUMO-protein ligase K-bZIP
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K05415  IFNB; interferon beta
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K21656  K12; KSHV protein K12
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K15308  TTP; tristetraprolin
       K05405  IL6; interleukin 6
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K21657  K4; KSHV macrophage inflammatory protein 2
       K04178  CCR3, CD193; C-C chemokine receptor type 3
       K04180  CCR5, CD195; C-C chemokine receptor type 5
       K04176  CCR1, CD191; C-C chemokine receptor type 1
       K21658  K4.1; KSHV protein vCCL3
       K04179  CCR4, CD194; C-C chemokine receptor type 4
       K21659  K6; KSHV protein K6
       K04183  CCR8, CDw198; C-C chemokine receptor type 8
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K21660  vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K21661  vIAP, K7; KSHV inhibitor of apoptosis protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K21662  vFLIP, K13, ORF71; KSHV FLICE inhibitory protein
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K21651  K15; KSHV signal transducing membrane protein
       K04451  TP53, P53; tumor protein p53
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K21663  vCyclin, ORF72; KSHV cyclin homolog
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K21664  vLANA, ORF73; KSHV latency-associated nuclear antigen
       K06751  MHC1; MHC class I antigen
       K21665  MIR1, K3; KSHV E3 ubiquitin-protein ligase MIR1 [EC:2.3.2.36]
       K21666  MIR2, K5; KSHV E3 ubiquitin-protein ligase MIR2 [EC:2.3.2.36]
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K06490  ICAM1, CD54; intercellular adhesion molecule 1
       K05413  CD86; CD86 antigen
       K07985  MIC; MHC class I-related protein
       K10071  CLEC2B; C-type lectin domain family 2 member B
       K02927  RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
       K02977  RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
       K04551  UBB; ubiquitin B
       K08770  UBC; ubiquitin C
       K08334  BECN, VPS30, ATG6; beclin
       K17889  ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K08343  ATG3; ubiquitin-like-conjugating enzyme ATG3
       K10435  MAP1LC; microtubule-associated protein 1 light chain
       K21667  vGPCR; KSHV G-protein coupled receptor
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K12365  PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K21860  K14; KSHV OX-2 membrane glycoprotein
       K21668  CD200R; cell surface glycoprotein CD200 receptor
       K21669  K1; KSHV protein K1
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K08893  HCK; hemopoietic cell kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K10030  IL8, CXCL8; interleukin 8
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K17901  RCAN1, MCIP1; calcipressin-1
       K18497  FGF2; fibroblast growth factor 2
       K05448  VEGFA; vascular endothelial growth factor A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K21670  vIL6, K2; KSHV interleukin 6
       K05466  ANGPT2; angiopoietin 2
       K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02105  CTNNB1; catenin beta 1
       K02620  TCF7, TCF-1; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04503  CCND1; G1/S-specific cyclin-D1
       K04377  MYC; Myc proto-oncogene protein
     05169 Epstein-Barr virus infection [PATH:ko05169]
     05165 Human papillomavirus infection [PATH:ko05165]
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:ko03000]
     03021 Transcription machinery [BR:ko03021]
     03019 Messenger RNA biogenesis [BR:ko03019]
       K00565  RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
       K13917  RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
       K04563  CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K00987  CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
       K01098  CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74]
       K14589  CMTR1, FTSJD2, MTR1; cap1 methyltransferase [EC:2.1.1.57]
       K14590  CMTR2, FTSJD1, AFT; cap2 methyltransferase [EC:2.1.1.296]
       K18776  MTR2, MT48; cap2 methyltransferase [EC:2.1.1.296]
       K18777  MTR3, MT57; cap3/cap4 methyltransferase [EC:2.1.1.-]
       K18708  FAM103A1; RNMT-activating mini protein
       K12882  NCBP1, CBP80; nuclear cap-binding protein subunit 1
       K12883  NCBP2, CBP20; nuclear cap-binding protein subunit 2
       K14397  NUDT21, CPSF5, CFIM25; cleavage and polyadenylation specificity factor subunit 5
       K14398  CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
       K14399  CLP1, HERB; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
       K14400  PCF11; pre-mRNA cleavage complex 2 protein Pcf11
       K14401  CPSF1, CFT1; cleavage and polyadenylation specificity factor subunit 1
       K14402  CPSF2, CFT2; cleavage and polyadenylation specificity factor subunit 2
       K14403  CPSF3, YSH1; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
       K14404  CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
       K14405  FIP1L1, FIP1; pre-mRNA 3'-end-processing factor FIP1
       K15541  MPE1; protein MPE1
       K15542  PFS2; polyadenylation factor subunit 2
       K14962  WDR82, SWD2, CPS35; COMPASS component SWD2
       K15543  REF2; RNA end formation protein 2
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K15544  SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
       K14406  CSTF1; cleavage stimulation factor subunit 1
       K14407  CSTF2, RNA15; cleavage stimulation factor subunit 2
       K14408  CSTF3, RNA14; cleavage stimulation factor subunit 3
       K06100  SYMPK; symplekin
       K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
       K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
       K11097  SNRPE, SME; small nuclear ribonucleoprotein E
       K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
       K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
       K25591  LSM10; U7 snRNA-associated Sm-like protein LSm10
       K25592  LSM11; U7 snRNA-associated Sm-like protein LSm11
       K18710  SLBP; histone RNA hairpin-binding protein
       K25593  CASP8AP2; CASP8-associated protein 2
       K15171  SUPT4H1, SPT4; transcription elongation factor SPT4
       K15172  SUPT5H, SPT5; transcription elongation factor SPT5
       K05925  METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
       K23960  METTL14; mRNA m6A methyltransferase non-catalytic subunit
       K24174  METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
       K11393  METTL16, METT10D; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
       K22824  WTAP; pre-mRNA-splicing regulator WTAP
       K22910  VIRMA; protein virilizer
       K13190  RBM15; RNA-binding protein 15
       K22909  ZC3H13; zinc finger CCCH domain-containing protein 13
       K15685  CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
       K14376  PAP; poly(A) polymerase [EC:2.7.7.19]
       K14079  PAPD4, GLD2; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
       K18709  TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
       K10683  BARD1; BRCA1-associated RING domain protein 1
       K13192  RBM26; RNA-binding protein 26
       K19469  FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
       K10767  ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
       K23600  TARDBP, TDP43; TAR DNA-binding protein 43
       K18711  DHX40, DDX40; ATP-dependent RNA helicase DHX40 [EC:3.6.4.13]
       K13102  KIN; DNA/RNA-binding protein KIN17
       K24975  METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
       K23040  METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
       K23033  TENT5A_B, FAM46A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
       K23034  TENT5C, FAM46C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
       K23035  TENT5D, FAM46D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
       K23038  ZC3H14; zinc finger CCCH domain-containing protein 14
       K27103  SRRT, ARS2; serrate RNA effector molecule
       K23039  NAB2; nuclear polyadenylated RNA-binding protein NAB2
       K12876  RBM8A, Y14; RNA-binding protein 8A
       K12877  MAGOH; protein mago nashi
       K12881  THOC4, ALY; THO complex subunit 4
       K12812  DDX39B, UAP56, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
       K13025  EIF4A3, FAL1; ATP-dependent RNA helicase [EC:3.6.4.13]
       K25178  CCDC174; coiled-coil domain-containing protein 174
       K14323  CASC3, MLN51; protein CASC3
       K14324  SAP18; histone deacetylase complex subunit SAP18
       K13114  PNN; pinin
       K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
       K14325  RNPS1; RNA-binding protein with serine-rich domain 1
       K13171  SRRM1, SRM160; serine/arginine repetitive matrix protein 1
       K12878  THOC1; THO complex subunit 1
       K12879  THOC2; THO complex subunit 2
       K12880  THOC3; THO complex subunit 3
       K13174  THOC5; THO complex subunit 5
       K13175  THOC6; THO complex subunit 6
       K13176  THOC7; THO complex subunit 7
       K18712  HPR1; THO complex subunit HPR1
       K18713  THP2; THO complex subunit THP2
       K18714  MFT1; THO complex subunit MFT1
       K23801  PCID2, THP1; nuclear mRNA export protein PCID2/THP1
       K10881  SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
       K11368  ENY2, DC6, SUS1; enhancer of yellow 2 transcription factor
       K10840  CETN2; centrin-2
       K16466  CETN3, CDC31; centrin-3
       K24317  MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
       K23719  SAC3; nuclear mRNA export protein SAC3
       K09291  TPR, MLP1, MLP2; nucleoprotein TPR
       K14298  RAE1, GLE2; mRNA export factor
       K14004  SEC13; protein transport protein SEC13
       K14302  NUP37; nuclear pore complex protein Nup37
       K14304  NUP85; nuclear pore complex protein Nup85
       K14305  NUP43; nuclear pore complex protein Nup43
       K14295  NUP50, NPAP60; nuclear pore complex protein Nup50
       K14308  NUP54, NUP57; nuclear pore complex protein Nup54
       K14306  NUP62, NSP1; nuclear pore complex protein Nup62
       K14318  NUP88; nuclear pore complex protein Nup88
       K14309  NUP93, NIC96; nuclear pore complex protein Nup93
       K14297  NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
       K14301  NUP107, NUP84; nuclear pore complex protein Nup107
       K14300  NUP133; nuclear pore complex protein Nup133
       K14311  NUP188; nuclear pore complex protein Nup188
       K14296  NUP153; nuclear pore complex protein Nup153
       K14312  NUP155, NUP170, NUP157; nuclear pore complex protein Nup155
       K14303  NUP160, NUP120; nuclear pore complex protein Nup160
       K14313  NUP35, NUP53; nuclear pore complex protein Nup53
       K14310  NUP205, NUP192; nuclear pore complex protein Nup205
       K14314  NUP210, GP210; nuclear pore complex protein Nup210
       K14317  NUP214, CAN; nuclear pore complex protein Nup214
       K14316  POM121, NUP121; nuclear pore complex protein Nup121
       K14307  NUPL1, NUP49; nucleoporin p58/p45
       K14321  NUPL2, NUP42, CG1; nucleoporin-like protein 2
       K14315  NDC1, TMEM48; nucleoporin NDC1
       K14299  SEH1; nucleoporin SEH1
       K12172  RANBP2, NUP358; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
       K03345  SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
       K14320  AAAS; aladin
       K18715  NUP159; nucleoporin NUP159
       K18716  NUP42, RIP1; nucleoporin NUP42
       K18717  ASM4, NUP59; nucleoporin ASM4
       K18718  NUP60; nucleoporin NUP60
       K18719  NUP82; nucleoporin NUP82
       K18720  NUP145; nucleoporin NUP145
       K18721  NUP1; nucleoporin NUP1
       K18722  NUP2; nucleoporin NUP2
       K18723  GLE1; nucleoporin GLE1
       K14284  NXF, TAP, MEX67; nuclear RNA export factor
       K14285  NXT1_2, P15; NTF2-related export protein 1/2
       K26564  NPAP1; nuclear pore-associated protein 1
       K14543  MTR2; mRNA transport regulator MTR2
       K18724  POM34; nucleoporin POM34
       K18725  POM152; nucleoporin POM152
       K14017  SNL1; HSP70 co-chaperone SNL1
       K07936  RAN; GTP-binding nuclear protein Ran
       K18646  ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
       K18647  ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
       K05475  TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K13208  ELAVL2_3_4; ELAV like protein 2/3/4
       K18726  FAF2, UBXD8; FAS-associated factor 2
       K13525  VCP, CDC48; transitional endoplasmic reticulum ATPase
       K21806  VCPKMT, METTL21D; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
       K18727  TNPO2, IPO3, KPNB2B; transportin-2
       K14290  XPO1, CRM1; exportin-1
       K18460  XPO7, EXP7; exportin-7
       K24115  RANBP17; Ran-binding protein 17
       K14319  RANGAP1; Ran GTPase-activating protein 1
       K14651  TAF15, NPL3; transcription initiation factor TFIID subunit 15
       K03259  EIF4E; translation initiation factor 4E
       K03257  EIF4A; translation initiation factor 4A
       K03260  EIF4G; translation initiation factor 4G
       K03258  EIF4B; translation initiation factor 4B
       K24086  EIF4H; translation initiation factor 4H
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K18644  EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
       K18645  EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
       K18728  EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
       K18729  ANGEL; protein angel
       K15516  FMR; fragile X mental retardation protein
       K05749  CYFIP; cytoplasmic FMR1 interacting protein
       K13133  GEMIN5; gem associated protein 5
       K14283  TACC3, maskin; transforming acidic coiled-coil-containing protein 3
       K02602  CPEB, ORB; cytoplasmic polyadenylation element-binding protein
       K11594  DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
       K18730  GIGYF; PERQ amino acid-rich with GYF domain-containing protein
       K13126  PABPC; polyadenylate-binding protein
       K14322  PAIP1; polyadenylate-binding protein-interacting protein 1
       K27470  PAIP2; polyadenylate-binding protein-interacting protein 2
       K12599  SKI2, SKIV2L; antiviral helicase SKI2 [EC:3.6.4.13]
       K18664  SLH1; antiviral helicase SLH1 [EC:3.6.4.13]
       K23041  DEAF1; deformed epidermal autoregulatory factor 1
       K07575  MCTS, TMA20; malignant T-cell-amplified sequence
       K24272  DENR, TMA22; density-regulated protein
       K16932  APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
       K24978  A1CF; APOBEC1 complementation factor
       K14294  WIBG, PYM; partner of Y14 and mago
       K12741  HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
       K14411  MSI; RNA-binding protein Musashi
       K14416  HBS1; elongation factor 1 alpha-like protein
       K06965  PELO, DOM34, pelA; protein pelota
       K14396  PABPN1, PABP2; polyadenylate-binding protein 2
       K18731  GFD1; mRNA transport factor GFD1
       K18655  DDX19, DBP5; ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13]
       K18656  DDX25, GRTH; ATP-dependent RNA helicase DDX25 [EC:3.6.4.13]
       K12867  SYF1, XAB2; pre-mRNA-splicing factor SYF1
       K18732  SARNP, CIP29, THO1; SAP domain-containing ribonucleoprotein
       K11493  RCC1; regulator of chromosome condensation
       K18733  LARP6; la-related protein 6
       K21772  PURA; transcriptional activator protein Pur-alpha
       K21799  PURB; transcriptional activator protein Pur-beta
       K22414  POLDIP3; polymerase delta-interacting protein 3
       K22415  ZC3H11; zinc finger CCCH domain-containing protein 11
       K23802  LENG8, THP3; SAC3 family protein LENG8/THP3
       K24823  PATL2; protein PAT1 homolog 2
       K23799  YRA2; RNA annealing protein YRA2
       K03265  ETF1, ERF1; peptide chain release factor subunit 1
       K03267  ERF3, GSPT; peptide chain release factor subunit 3
       K14326  UPF1, RENT1; regulator of nonsense transcripts 1 [EC:3.6.4.13 5.6.2.3]
       K14327  UPF2, RENT2; regulator of nonsense transcripts 2
       K14328  UPF3, RENT3; regulator of nonsense transcripts 3
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K08873  SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
       K11125  SMG5, EST1B; protein SMG5
       K11124  SMG6, EST1A; protein SMG6 [EC:3.1.-.-]
       K14409  SMG7, EST1C; protein SMG7
       K18734  SMG8; protein SMG8
       K18735  SMG9; protein SMG9
       K19539  SECISBP2, SBP2; selenocysteine insertion sequence-binding protein 2
       K20101  DHX34; ATP-dependent RNA helicase DHX34 [EC:3.6.4.13]
       K24887  GTPBP1; GTP-binding protein 1
       K18736  SHE2; SWI5-dependent HO expression protein 2
       K18737  SHE3; SWI5-dependent HO expression protein 3
       K14844  PUF6; pumilio homology domain family member 6
       K18738  HEK; heterogeneous nuclear rnp K-like protein
       K10357  MYO5; myosin V
       K18658  ASH1; transcriptional regulatory protein ASH1
       K18739  BICD; protein bicaudal D
       K18740  EXD1, EGL; exonuclease 3'-5' domain-containing protein 1
       K05692  ACTB_G1; actin beta/gamma 1
       K17269  MBP; myelin basic protein
       K07606  VIM; vimentin
       K14739  MT1_2; metallothionein 1/2
       K04377  MYC; Myc proto-oncogene protein
       K18659  BCD; homeotic protein bicoid
       K05495  GDF1; growth differentiation factor 1
       K10180  TBX6; T-box protein 6
       K18741  NANOS1, NOS1; protein nanos 1
       K18742  OSK; maternal effect protein oskar
       K02524  K10; DNA binding protein (fs(1)K10, female sterile(1)K10)
       K02447  GRK; protein gruken
       K09090  HESN; hairy and enhancer of split, invertebrate
       K12965  ZBP1, DAI; Z-DNA binding protein 1
       K13210  FUBP; far upstream element-binding protein
       K03231  EEF1A; elongation factor 1-alpha
       K03233  EEF1G; elongation factor 1-gamma
       K13158  HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
       K16220  HAX1; HCLS1-associated protein X-1
       K15044  AGFG1; Arf-GAP domain and FG repeats-containing protein 1
       K17597  STAU; double-stranded RNA-binding protein Staufen
       K13197  IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
       K13218  PTBP1, PTB; polypyrimidine tract-binding protein 1
       K03102  SQD; squid
       K13162  PCBP2; poly(rC)-binding protein 2
       K21444  PCBP3_4; poly(rC)-binding protein 3/4
       K18743  CAPRIN1, GPIAP1; caprin-1
       K18744  CAPRIN2, EEG1; caprin-2
       K02177  BRU; bruno
       K18745  EXU; maternal protein exuperantia
       K09276  YBX1, NSEP1; Y-box-binding protein 1
       K18746  CUP; protein cup
       K18747  SXL; protein sex-lethal
       K18748  SSD1; protein SSD1
       K12618  XRN1, SEP1, KEM1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
       K11593  ELF2C, AGO; eukaryotic translation initiation factor 2C
       K17642  DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]
       K12614  DDX6, RCK, DHH1; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
       K15686  MEX3, RKHD; RNA-binding protein MEX3 [EC:2.3.2.27]
       K08290  FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
       K18749  LSM14, RAP55, SCD6; protein LSM14
       K12889  PCBP1; poly(rC)-binding protein 1
       K16682  AJUBA, LIMD1, WTIP; LIM domain-containing protein
       K18750  APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
       K18422  MOV10; helicase MOV-10 [EC:3.6.4.13]
       K18751  PNRC2; proline-rich nuclear receptor coactivator 2
       K18752  TNPO1, IPO2, KPNB2; transportin-1
       K15308  TTP; tristetraprolin
       K18753  ZFP36L; butyrate response factor
       K18754  LIN28; protein lin-28
       K04533  HD; huntingtin
       K18755  IPO8, RANBP8; importin-8
       K18756  BICC1, BICC; protein bicaudal C
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K18757  LARP1; la-related protein 1
       K23625  ATXN2_2L; ataxin 2/2L
       K12613  DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
       K12610  DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
       K12611  DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
       K12612  DCP1; mRNA-decapping enzyme subunit 1
       K12620  LSM1; U6 snRNA-associated Sm-like protein LSm1
       K12621  LSM2; U6 snRNA-associated Sm-like protein LSm2
       K12622  LSM3; U6 snRNA-associated Sm-like protein LSm3
       K12623  LSM4; U6 snRNA-associated Sm-like protein LSm4
       K12624  LSM5; U6 snRNA-associated Sm-like protein LSm5
       K12625  LSM6; U6 snRNA-associated Sm-like protein LSm6
       K12626  LSM7; U6 snRNA-associated Sm-like protein LSm7
       K12627  LSM8; U6 snRNA-associated Sm-like protein LSm8
       K10407  KLC; kinesin light chain
       K07374  TUBA; tubulin alpha
       K18412  TNRC6, GW182; trinucleotide repeat-containing gene 6 protein
       K12604  CNOT1, NOT1; CCR4-NOT transcription complex subunit 1
       K12605  CNOT2, NOT2; CCR4-NOT transcription complex subunit 2
       K12580  CNOT3, NOT3; CCR4-NOT transcription complex subunit 3
       K10643  CNOT4, NOT4, MOT2; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
       K12603  CNOT6, CCR4; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
       K12581  CNOT7_8, CAF1, POP2; CCR4-NOT transcription complex subunit 7/8
       K26671  GARRE1; granule associated Rac and RHOG effector protein 1
       K18758  DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
       K12571  PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
       K12572  PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
       K14443  TOB; protein Tob/BTG
       K12617  PATL1, PAT1; DNA topoisomerase 2-associated protein PAT1
       K18759  EDC1_2; enhancer of mRNA-decapping protein 1/2
       K12615  EDC3; enhancer of mRNA-decapping protein 3
       K12616  EDC4; enhancer of mRNA-decapping protein 4
       K18760  NANOS2, NOS2; protein nanos 2
       K18761  NANOS3, NOS3; protein nanos 3
       K10651  TRIM21, SSA1; tripartite motif-containing protein 21 [EC:2.3.2.27]
       K12035  TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K18762  ZAR1; zygote arrest protein 1
       K20102  YTHDF; YTH domain-containing family protein
       K13201  TIA1, TIAL1; nucleolysin TIA-1/TIAR
       K17265  G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.3 3.6.4.13]
       K24983  G3BP2; Ras GTPase-activating protein-binding protein 2
       K15026  EIF2A; translation initiation factor 2A
       K03253  EIF3B; translation initiation factor 3 subunit B
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K14753  RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K11407  HDAC6; histone deacetylase 6 [EC:3.5.1.98]
       K18404  TDRD3; tudor domain-containing protein 3
       K18763  LARP4; la-related protein 4
       K12619  XRN2, RAT1; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
       K20553  XRN4; 5'-3' exoribonuclease 4 [EC:3.1.13.-]
       K16855  NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
       K12584  DCPS, DCS; m7GpppX diphosphatase [EC:3.6.1.59]
       K25168  HELZ; helicase with zinc finger domain [EC:3.6.4.-]
       K07573  CSL4, EXOSC1; exosome complex component CSL4
       K03679  RRP4, EXOSC2; exosome complex component RRP4
       K03681  RRP40, EXOSC3; exosome complex component RRP40
       K11600  RRP41, EXOSC4, SKI6; exosome complex component RRP41
       K12590  RRP46, EXOSC5; exosome complex component RRP46
       K12587  MTR3, EXOSC6; exosome complex component MTR3
       K12589  RRP42, EXOSC7; exosome complex component RRP42
       K12586  RRP43, EXOSC8, OIP2; exosome complex component RRP43
       K03678  RRP45, EXOSC9; exosome complex component RRP45
       K12585  DIS3, RRP44; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
       K18681  DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
       K12591  RRP6, EXOSC10; exosome complex exonuclease RRP6 [EC:3.1.13.-]
       K12592  C1D, LRP1; exosome complex protein LRP1
       K12593  MPHOSPH6, MPP6; M-phase phosphoprotein 6, animal type
       K12594  MPP6; M-phase phosphoprotein 6, fungi type
       K12595  SKI7; superkiller protein 7
       K20103  DDX60; ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]
       K03514  PAPD5_7, TRF4; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
       K12597  AIR1_2; protein AIR1/2
       K12598  MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:3.6.4.13]
       K12596  TRF5; poly(A) RNA polymerase
       K12600  SKI3, TTC37; superkiller protein 3
       K12601  SKI8; superkiller protein 8
       K12602  WDR61, REC14, SKI8; WD repeat-containing protein 61
       K12606  RCD1, CNOT9, CAF40; CCR4-NOT transcription complex subunit 9
       K12607  CNOT10; CCR4-NOT transcription complex subunit 10
       K12608  CAF16; CCR4-NOT complex subunit CAF16
       K12609  CAF120; CCR4-NOT transcriptional complex subunit CAF120
       K01148  PARN, PNLDC1; poly(A)-specific ribonuclease [EC:3.1.13.4]
       K14442  DHX36, RHAU; ATP-dependent RNA helicase DHX36 [EC:3.6.4.13]
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K18764  NOCT, CCRN4L; nocturnin [EC:3.1.3.108]
       K18416  THEX1, ERI1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
       K18417  ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
       K19612  PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
       K22416  IREB2; iron-responsive element-binding protein 2
       K26109  NRDE2; nuclear exosome regulator NRDE2
       K27396  SMG; protein Smaug
       K27407  VTS1; RNA-binding protein VTS1
       K01168  RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
       K10787  RNASE3, ECP; eosinophil cationic protein [EC:3.1.27.-]
       K16632  RNASE4; ribonuclease 4 [EC:3.1.27.-]
       K01172  RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
       K16633  RNASE11; ribonuclease 11 [EC:3.1.27.-]
       K18668  ZC3H12, MCPIP; ribonuclease ZC3H12 [EC:3.1.-.-]
       K23175  RNU2; ribonuclease U2 [EC:4.6.1.20]
       K08300  rne; ribonuclease E [EC:3.1.26.12]
       K08301  rng, cafA; ribonuclease G [EC:3.1.26.-]
       K03685  rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
       K12574  rnj; ribonuclease J [EC:3.1.-.-]
       K18682  rny; ribonucrease Y [EC:3.1.-.-]
       K12573  rnr, vacB; ribonuclease R [EC:3.1.13.1]
       K01167  rnaSA; ribonuclease T1 [EC:4.6.1.24]
       K13288  orn, REX2, REXO2; oligoribonuclease [EC:3.1.-.-]
       K03698  cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-]
       K03732  rhlB; ATP-dependent RNA helicase RhlB [EC:3.6.4.13]
       K11927  rhlE; ATP-dependent RNA helicase RhlE [EC:3.6.4.13]
       K05592  deaD, cshA; ATP-dependent RNA helicase DeaD [EC:3.6.4.13]
       K18692  cshB; ATP-dependent RNA helicase CshB [EC:3.6.4.13]
       K03654  recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
       K01689  ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11]
       K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
       K03628  rho; transcription termination factor Rho
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K04043  dnaK, HSPA9; molecular chaperone DnaK
       K04077  groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
       K03666  hfq; host factor-I protein
       K00937  ppk1; polyphosphate kinase [EC:2.7.4.1]
       K22468  ppk2; polyphosphate kinase [EC:2.7.4.34]
       K00970  pcnB; poly(A) polymerase [EC:2.7.7.19]
       K08311  nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
       K03563  csrA; carbon storage regulator
       K18765  csrD; RNase E specificity factor CsrD
       K02553  rraA, menG; regulator of ribonuclease activity A
       K09893  rraB; regulator of ribonuclease activity B
       K06958  rapZ; RNase adapter protein RapZ
       K03727  helY; ATP-dependent RNA helicase HelY [EC:3.6.4.-]
       K18502  dsrA; small regulatory RNA DsrA
       K18503  chiX, sroB; small regulatory RNA ChiX
       K18504  arcZ; small regulatory RNA ArcZ
       K15841  glmY; small regulatory RNA GlmY
       K18505  glmZ; small regulatory RNA GlmZ
       K18506  sgrS; small regulatory RNA SgrS
       K18507  ryhB; small regulatory RNA RyhB
       K18508  rybB; small regulatory RNA RybB
       K18509  rydC; small regulatory RNA RydC
       K18510  fnrS; small regulatory RNA FnrS
       K18511  micA; small regulatory RNA MicA
       K18512  micC; small regulatory RNA MicC
       K18513  micF; small regulatory RNA MicF
       K18514  mgrR; small regulatory RNA MgrR
       K18515  csrB; small regulatory RNA CsrB
       K18516  csrC; small regulatory RNA CsrC
       K18517  dicF; small regulatory RNA DicF
       K18518  rprA; small regulatory RNA RprA
       K18519  rseX; small regulatory RNA RseX
       K18520  cyaR, ryeE; small regulatory RNA CyaR
       K18521  gcvB; small regulatory RNA GcvB
       K18522  omrA, rygA; small regulatory RNA OmrA
       K18523  omrB, rygB; small regulatory RNA OmrB
       K18525  gadY; small regulatory RNA GadY
       K18526  istR; sRNA antisense regulator of TisB protein
       K18527  spf; small regulatory RNA Spot 42
       K18528  oxyS; small regulatory RNA OxyS
       K03725  K03725; putative ATP-dependent RNA helicase [EC:3.6.4.-]
     03041 Spliceosome [BR:ko03041]
     03011 Ribosome [BR:ko03011]
     03009 Ribosome biogenesis [BR:ko03009]
     03016 Transfer RNA biogenesis [BR:ko03016]
     03012 Translation factors [BR:ko03012]
     03110 Chaperones and folding catalysts [BR:ko03110]
     04131 Membrane trafficking [BR:ko04131]
     04121 Ubiquitin system [BR:ko04121]
     03051 Proteasome [BR:ko03051]
     03032 DNA replication proteins [BR:ko03032]
     03036 Chromosome and associated proteins [BR:ko03036]
     03400 DNA repair and recombination proteins [BR:ko03400]
     03029 Mitochondrial biogenesis [BR:ko03029]
 
   09183 Protein families: signaling and cellular processes
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 18, 2024