KEGG Orthology (KO)

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 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ko00061]
     00062 Fatty acid elongation [PATH:ko00062]
     00071 Fatty acid degradation [PATH:ko00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
     00073 Cutin, suberine and wax biosynthesis [PATH:ko00073]
     00100 Steroid biosynthesis [PATH:ko00100]
     00120 Primary bile acid biosynthesis [PATH:ko00120]
     00121 Secondary bile acid biosynthesis [PATH:ko00121]
     00140 Steroid hormone biosynthesis [PATH:ko00140]
     00561 Glycerolipid metabolism [PATH:ko00561]
     00564 Glycerophospholipid metabolism [PATH:ko00564]
       K00006  GPD1; glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]
       K00057  gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
       K00105  E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21]
       K00111  glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
       K00112  glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
       K00113  glpC; glycerol-3-phosphate dehydrogenase subunit C
       K00629  GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
       K13506  GPAT3_4, AGPAT9, AGPAT6; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
       K13507  GAT; glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase [EC:2.3.1.15 2.3.1.42]
       K00630  ATS1; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
       K13508  GPAT; glycerol-3-phosphate acyltransferase [EC:2.3.1.15 2.3.1.198]
       K00631  plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
       K08591  plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
       K00655  plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
       K13509  AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
       K13523  AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
       K19007  AGPAT5; lysophosphatidiate acyltransferase [EC:2.3.1.51]
       K13513  LCLAT1, AGPAT8; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
       K13517  MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
       K13519  LPT1, ALE1; lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K22831  LOA1; 1-acylglycerol-3-phosphate O-acyltransferase [EC:2.3.1.51]
       K00649  GNPAT; glyceronephosphate O-acyltransferase [EC:2.3.1.42]
       K06123  AYR1; 1-acylglycerone phosphate reductase [EC:1.1.1.101]
       K00980  tagD; glycerol-3-phosphate cytidylyltransferase [EC:2.7.7.39]
       K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
       K01080  PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
       K15728  LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
       K18693  DPP1, DPPL, PLPP4_5; diacylglycerol diphosphate phosphatase / phosphatidate phosphatase [EC:3.1.3.81 3.1.3.4]
       K00901  dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K07029  dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K16368  DGK1; diacylglycerol kinase (CTP) [EC:2.7.1.174]
       K00994  CHPT1, CPT1; diacylglycerol cholinephosphotransferase [EC:2.7.8.2]
       K13644  CEPT1; choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2]
       K01114  plc; phospholipase C [EC:3.1.4.3]
       K16619  plc, cpa; phospholipase C / alpha-toxin [EC:3.1.4.3]
       K18694  PGC1; phosphatidylglycerol phospholipase C [EC:3.1.4.-]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K16860  PLD3_4; phospholipase D3/4 [EC:3.1.4.4]
       K17717  pld; phospholipase D [EC:3.1.4.4]
       K00650  LCAT; lecithin-cholesterol acyltransferase [EC:2.3.1.43]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
       K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
       K13512  LPCAT4, AGPAT7; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
       K13515  LPCAT3, MBOAT5; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
       K16818  DAD1; phospholipase A1 [EC:3.1.1.32]
       K22389  LCAT3; phospholipase A1 [EC:3.1.1.32]
       K06128  LYPLA1; lysophospholipase I [EC:3.1.1.5]
       K06129  LYPLA3; lysophospholipase III [EC:3.1.1.5]
       K06130  LYPLA2; lysophospholipase II [EC:3.1.1.5]
       K13333  PLB; lysophospholipase [EC:3.1.1.5]
       K01048  pldB; lysophospholipase [EC:3.1.1.5]
       K14676  NTE, NRE; lysophospholipid hydrolase [EC:3.1.1.5]
       K18695  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]
       K18696  GDE1; glycerophosphodiester phosphodiesterase [EC:3.1.4.46]
       K01126  E3.1.4.46, glpQ, ugpQ; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
       K00623  CHAT; choline O-acetyltransferase [EC:2.3.1.6]
       K01049  ACHE; acetylcholinesterase [EC:3.1.1.7]
       K00866  CKI1; choline kinase [EC:2.7.1.32]
       K14156  CHK; choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
       K06124  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75]
       K00968  PCYT1; choline-phosphate cytidylyltransferase [EC:2.7.7.15]
       K00993  EPT1; ethanolaminephosphotransferase [EC:2.7.8.1]
       K05939  aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
       K00894  ETNK, EKI; ethanolamine kinase [EC:2.7.1.82]
       K00967  PCYT2; ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14]
       K05929  E2.1.1.103, NMT; phosphoethanolamine N-methyltransferase [EC:2.1.1.103]
       K04019  eutA; ethanolamine utilization protein EutA
       K03735  eutB; ethanolamine ammonia-lyase large subunit [EC:4.3.1.7]
       K03736  eutC; ethanolamine ammonia-lyase small subunit [EC:4.3.1.7]
       K14286  AGXT2L1, ETNPPL; ethanolamine-phosphate phospho-lyase [EC:4.2.3.2]
       K00551  PEMT; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
       K16369  CHO2; phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]
       K00550  PLMT; phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.71]
       K00570  pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
       K01521  cdh; CDP-diacylglycerol pyrophosphatase [EC:3.6.1.26]
       K00981  E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]
       K01004  pcs; phosphatidylcholine synthase [EC:2.7.8.24]
       K00998  pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
       K17103  CHO1, pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
       K08729  PTDSS1; phosphatidylserine synthase 1 [EC:2.7.8.-]
       K08730  PTDSS2; phosphatidylserine synthase 2 [EC:2.7.8.29]
       K01613  psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]
       K00995  pgsA, PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
       K01094  GEP4; phosphatidylglycerophosphatase GEP4 [EC:3.1.3.27]
       K01095  pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
       K01096  pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.1.3.81 3.1.3.4 3.6.1.27]
       K18697  pgpC; phosphatidylglycerophosphatase C [EC:3.1.3.27]
       K06131  clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
       K06132  clsC; cardiolipin synthase C [EC:2.7.8.-]
       K08744  CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
       K13511  TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
       K13535  CLD1; cardiolipin-specific phospholipase [EC:3.1.1.-]
       K13514  LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
       K00999  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]
       K13516  MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
       K13621  BTA1; betaine lipid synthase
       K13622  btaA; S-adenosylmethionine-diacylglycerol 3-amino-3-carboxypropyl transferase
       K13623  btaB; S-adenosylmethionine-diacylgycerolhomoserine-N-methlytransferase
       K00096  araM, egsA; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
       K17104  E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
       K17105  E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
       K19664  carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
       K19665  pssA; archaetidylserine synthase [EC:2.7.8.38]
       K17830  GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
     00565 Ether lipid metabolism [PATH:ko00565]
       K00803  AGPS, agpS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]
       K06123  AYR1; 1-acylglycerone phosphate reductase [EC:1.1.1.101]
       K01080  PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
       K00993  EPT1; ethanolaminephosphotransferase [EC:2.7.8.1]
       K00994  CHPT1, CPT1; diacylglycerol cholinephosphotransferase [EC:2.7.8.2]
       K13644  CEPT1; choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
       K13512  LPCAT4, AGPAT7; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
       K08743  ENPP6; ectonucleotide pyrophosphatase/phosphodiesterase family member 6 [EC:3.1.4.-]
       K01122  ENPP2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [EC:3.1.4.39]
       K22387  GDPD1_3, GDE4_7; lysophospholipase D [EC:3.1.4.39]
       K18575  TMEM86B; alkenylglycerophosphocholine hydrolase [EC:3.3.2.2]
       K01114  plc; phospholipase C [EC:3.1.4.3]
       K16619  plc, cpa; phospholipase C / alpha-toxin [EC:3.1.4.3]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K16860  PLD3_4; phospholipase D3/4 [EC:3.1.4.4]
       K17717  pld; phospholipase D [EC:3.1.4.4]
       K04628  CGT, UGT8; ceramide galactosyltransferase [EC:2.4.1.47]
       K01019  GAL3ST1; galactosylceramide sulfotransferase [EC:2.8.2.11]
       K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
       K13519  LPT1, ALE1; lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-]
       K16794  PAFAH1B1, LIS1; platelet-activating factor acetylhydrolase IB subunit alpha
       K16795  PAFAH1B2_3; platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47]
       K01062  PLA2G7, PAFAH; platelet-activating factor acetylhydrolase [EC:3.1.1.47]
     00600 Sphingolipid metabolism [PATH:ko00600]
     00590 Arachidonic acid metabolism [PATH:ko00590]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K15729  PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
       K05309  PTGES2; microsomal prostaglandin-E synthase 2 [EC:5.3.99.3]
       K15730  PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
       K00079  CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
       K00081  CBR2; carbonyl reductase 2 [EC:1.1.1.184]
       K00084  CBR3; carbonyl reductase 3 [EC:1.1.1.184]
       K15717  PRXL2B, FAM213B; prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]
       K23486  PGFS; 9,11-endoperoxide prostaglandin H2 reductase [EC:1.1.1.-]
       K01832  TBXAS1, CYP5A; thromboxane-A synthase [EC:5.3.99.5]
       K01830  PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
       K04097  HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
       K01831  PTGIS, CYP8A; prostacyclin synthase [EC:5.3.99.4]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K01254  LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
       K17726  CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:1.14.14.78 1.14.14.79 1.14.14.94]
       K00807  LTC4S; leukotriene-C4 synthase [EC:4.4.1.20]
       K18592  GGT1_5, CD224; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
       K00432  gpx; glutathione peroxidase [EC:1.11.1.9]
       K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
       K07422  CYP2U1; cytochrome P450 family 2 subfamily U polypeptide 1
       K07425  CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
       K17721  CYP2C19; cytochrome P450 family 2 subfamily C polypeptide 19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
       K17728  CYP4F8; cytochrome P450 family 4 subfamily F polypeptide 8 [EC:1.14.14.1]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K08021  ALOX12B; arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
       K08022  ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
       K17709  CYP2B6; cytochrome P450 family 2 subfamily B polypeptide 6 [EC:1.14.13.-]
       K07412  CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
       K07413  CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
       K17718  CYP2C8; cytochrome P450 family 2 subfamily C polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
       K08726  EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
       K19246  loxA; arachidonate 15-lipoxygenase [EC:1.13.11.33]
     00591 Linoleic acid metabolism [PATH:ko00591]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
       K15718  LOX1_5; linoleate 9S-lipoxygenase [EC:1.13.11.58]
       K00454  LOX2S; lipoxygenase [EC:1.13.11.12]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
       K21794  E1.13.11.45; linoleate 11-lipoxygenase [EC:1.13.11.45]
       K17862  PPOC; linoleate 10R-lipoxygenase [EC:1.13.11.62]
       K17863  PPOA; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase [EC:1.13.11.60 5.4.4.5]
       K17864  LDS; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase [EC:1.13.11.60 5.4.4.6]
       K07409  CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
       K17718  CYP2C8; cytochrome P450 family 2 subfamily C polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
       K17721  CYP2C19; cytochrome P450 family 2 subfamily C polypeptide 19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
       K07413  CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
       K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
       K17689  CYP3A4; cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.13.-]
       K07424  CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
       K00508  E1.14.19.3; linoleoyl-CoA desaturase [EC:1.14.19.3]
       K08262  E1.14.19.39; acyl-lipid delta12-acetylenase [EC:1.14.19.39]
     00592 alpha-Linolenic acid metabolism [PATH:ko00592]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
       K16818  DAD1; phospholipase A1 [EC:3.1.1.32]
       K22389  LCAT3; phospholipase A1 [EC:3.1.1.32]
       K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
       K00454  LOX2S; lipoxygenase [EC:1.13.11.12]
       K01723  AOS; hydroperoxide dehydratase [EC:4.2.1.92]
       K10525  AOC; allene oxide cyclase [EC:5.3.99.6]
       K05894  OPR; 12-oxophytodienoic acid reductase [EC:1.3.1.42]
       K10526  OPCL1; OPC-8:0 CoA ligase 1 [EC:6.2.1.-]
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K10527  MFP2; enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211]
       K00632  fadA, fadI; acetyl-CoA acyltransferase [EC:2.3.1.16]
       K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
       K08241  E2.1.1.141; jasmonate O-methyltransferase [EC:2.1.1.141]
       K10528  HPL; hydroperoxide lyase [EC:4.1.2.-]
       K18857  ADH1; alcohol dehydrogenase class-P [EC:1.1.1.1]
       K18858  CHAT; (Z)-3-hexen-1-ol acetyltransferase [EC:2.3.1.195]
       K00224  CEQORH; chloroplastic oxoene reductase [EC:1.3.1.-]
       K10529  DOX; alpha-dioxygenase [EC:1.14.99.-]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ko01040]
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system [PATH:ko02020]
     04014 Ras signaling pathway [PATH:ko04014]
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22603  FGF19; fibroblast growth factor 19
       K22429  FGF21; fibroblast growth factor 21
       K22428  FGF23; fibroblast growth factor 23
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K09593  GAB1; GRB2-associated-binding protein 1
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
       K07362  LAT; linker for activation of T cells
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K02183  CALM; calmodulin
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07831  MRAS; Ras-related protein M-Ras
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K12380  RASA3; Ras GTPase-activating protein 3
       K17630  RASA4, CAPRI; Ras GTPase-activating protein 4
       K17631  SYNGAP, RASA5; Ras/Rap GTPase-activating protein SynGAP
       K17632  RASAL1; RAS protein activator-like 1
       K17633  RASAL2; RAS protein activator-like 2
       K17634  RASAL3; RAS protein activator-like 3
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05736  PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K04513  RHOA; Ras homolog gene family, member A
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K02158  BAD; Bcl-2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K12358  FOXO4; forkhead box protein O4
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K05702  AF6, MLLT4; afadin
       K19613  SHOC2, SUR8; leucine-rich repeat protein SHOC2
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K13618  PLA1A; phospholipase A1 member A [EC:3.1.1.-]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K02678  ETS1, pnt; C-ets-1
       K21932  ETS2; C-ets-2
       K10632  BRAP; BRCA1-associated protein [EC:2.3.2.27]
       K14958  KSR1; kinase suppressor of Ras 1
       K18529  KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
       K08019  RAPGEF5; Rap guanine nucleotide exchange factor 5
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K17635  RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1
       K17636  RGL2; ral guanine nucleotide dissociation stimulator-like 2
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K17637  EXOC2, SEC5; exocyst complex component 2
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K09254  REL; c-Rel proto-oncogene protein
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K17638  RIN1; Ras and Rab interactor 1
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K08887  ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
       K07887  RAB5A; Ras-related protein Rab-5A
       K07888  RAB5B; Ras-related protein Rab-5B
       K07889  RAB5C; Ras-related protein Rab-5C
       K07941  ARF6; ADP-ribosylation factor 6
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
       K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04852  CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04854  CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K09784  EREG; epiregulin
       K09782  AREG; amphiregulin
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22603  FGF19; fibroblast growth factor 19
       K22429  FGF21; fibroblast growth factor 21
       K22428  FGF23; fibroblast growth factor 23
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04370  LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04377  MYC; Myc proto-oncogene protein
       K04378  SRF; serum response factor
       K04379  FOS; proto-oncogene protein c-fos
       K04380  MAPT, TAU; microtubule-associated protein tau
       K04381  STMN1; stathmin
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K04386  IL1R1, CD121a; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K04391  CD14; monocyte differentiation antigen CD14
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K02308  DAXX; death-associated protein 6
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04405  ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
       K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
       K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
       K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K04411  STK4, MST1; serine/threonine kinase 4
       K04412  STK3, MST2; serine/threonine kinase 3
       K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
       K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
       K04423  MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
       K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
       K04425  MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
       K04435  MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
       K04436  MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
       K04437  FLNA; filamin
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04439  ARRB; beta-arrestin
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K16510  RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04451  TP53, P53; tumor protein p53
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K04453  MAX; Max protein
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04455  HSPB1; heat shock protein beta-1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04457  PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
       K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
       K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
       K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
       K21278  DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K21946  DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
       K18498  DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
       K20216  DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
       K17614  DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
       K04460  PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
       K04462  MECOM, EVI1; ecotropic virus integration site 1 protein
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K09253  RELB; transcription factor RelB
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04016 MAPK signaling pathway - plant [PATH:ko04016]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04341 Hedgehog signaling pathway - fly [PATH:ko04341]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway - fly [PATH:ko04391]
     04392 Hippo signaling pathway - multiple species [PATH:ko04392]
     04370 VEGF signaling pathway [PATH:ko04370]
       K05448  VEGFA; vascular endothelial growth factor A
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K08273  SH2D2A, VRAP; SH2 domain protein 2A
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K17447  SHC2; SHC-transforming protein 2
       K05760  PXN; paxillin
       K04393  CDC42; cell division control protein 42
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
       K04455  HSPB1; heat shock protein beta-1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02158  BAD; Bcl-2-antagonist of cell death
     04371 Apelin signaling pathway [PATH:ko04371]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04072 Phospholipase D signaling pathway [PATH:ko04072]
       K04357  EGF; epidermal growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05461  KITLG; KIT ligand
       K04526  INS; insulin
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K09593  GAB1; GRB2-associated-binding protein 1
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07831  MRAS; Ras-related protein M-Ras
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04513  RHOA; Ras homolog gene family, member A
       K07937  ARF1; ADP-ribosylation factor 1
       K07941  ARF6; ADP-ribosylation factor 6
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06856  IGH; immunoglobulin heavy chain
       K08089  FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
       K08090  MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
       K07983  FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K13509  AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
       K13523  AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
       K19007  AGPAT5; lysophosphatidiate acyltransferase [EC:2.3.1.51]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K00901  dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K01080  PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K09821  AGT, SERPINA8; angiotensinogen
       K05242  AVP; arginine vasopressin
       K10030  IL8, CXCL8; interleukin 8
       K04166  AGTR1; angiotensin II receptor type 1
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04603  GRM1; metabotropic glutamate receptor 1
       K04605  GRM2; metabotropic glutamate receptor 2
       K04606  GRM3; metabotropic glutamate receptor 3
       K04607  GRM4; metabotropic glutamate receptor 4
       K04604  GRM5; metabotropic glutamate receptor 5
       K04608  GRM6; metabotropic glutamate receptor 6
       K04609  GRM7; metabotropic glutamate receptor 7
       K04610  GRM8; metabotropic glutamate receptor 8
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04228  AVPR2; arginine vasopressin receptor 2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04262  PTGFR; prostaglandin F receptor
       K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
       K05050  CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K18441  CYTH; cytohesin
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K01528  DNM1_3; dynamin 1/3 [EC:3.6.5.5]
       K23484  DNM2; dynamin 2 [EC:3.6.5.5]
     04071 Sphingolipid signaling pathway [PATH:ko04071]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP-PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
     04214 Apoptosis - fly [PATH:ko04214]
     04215 Apoptosis - multiple species [PATH:ko04215]
     04216 Ferroptosis [PATH:ko04216]
     04217 Necroptosis [PATH:ko04217]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K09849  TRAF5; TNF receptor-associated factor 5
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K10630  RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
       K11974  RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
       K20894  SHARPIN; shank-associated RH domain-interacting protein
       K17595  SPATA2; spermatogenesis-associated protein 2
       K08601  CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
       K21421  NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K05864  PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K00261  GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
       K01915  glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
       K00688  PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K00522  FTH1; ferritin heavy chain [EC:1.16.3.2]
       K13625  FTL; ferritin light chain
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K12350  SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
       K08849  MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
       K15637  PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
       K17065  DNM1L; dynamin 1-like protein [EC:3.6.5.5]
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K04519  IL1B; interleukin 1 beta
       K12191  CHMP2A; charged multivesicular body protein 2A
       K12192  CHMP2B; charged multivesicular body protein 2B
       K12193  VPS24, CHMP3; charged multivesicular body protein 3
       K12194  CHMP4, SNF7, VPS32; charged multivesicular body protein 4
       K12195  CHMP6, VPS20; charged multivesicular body protein 6
       K12196  VPS4; vacuolar protein-sorting-associated protein 4
       K12197  CHMP1, VPS46, DID2; charged multivesicular body protein 1
       K12198  CHMP5, VPS60; charged multivesicular body protein 5
       K15053  CHMP7; charged multivesicular body protein 7
       K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
       K04383  IL1A; interleukin 1 alpha
       K12967  IL33; interleukin 33
       K10802  HMGB1; high mobility group protein B1
       K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K20703  FAF1; FAS-associated factor 1
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K04687  IFNG; interferon gamma
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04692  STAT3; signal transducer and activator of transcription 3
       K11222  STAT4; signal transducer and activator of transcription 4
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11225  STAT6; signal transducer and activator of transcription 6
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K10160  TLR4, CD284; toll-like receptor 4
       K05409  TIRP, TRAM; TRIF-related adaptor molecule
       K05842  TRIF; toll-like receptor adapter molecule 1
       K05401  TLR3, CD283; toll-like receptor 3
       K12965  ZBP1, DAI; Z-DNA binding protein 1
       K21634  USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
       K14381  SQSTM1; sequestosome 1
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
       K10798  PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
       K04726  BID; BH3 interacting domain death agonist
       K02159  BAX; apoptosis regulator BAX
       K04727  AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
       K11251  H2A; histone H2A
       K03767  PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
       K02161  BCL2; apoptosis regulator Bcl-2
     04115 p53 signaling pathway [PATH:ko04115]
     04218 Cellular senescence [PATH:ko04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
   09151 Immune system
     04640 Hematopoietic cell lineage [PATH:ko04640]
     04610 Complement and coagulation cascades [PATH:ko04610]
     04611 Platelet activation [PATH:ko04611]
       K04264  TBXA2R; thromboxane A2 receptor
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12757  MYL12; myosin regulatory light chain 12
       K05215  P2RX1; P2X purinoceptor 1
       K16056  ORAI1; calcium release-activated calcium channel protein 1
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K16059  STIM1; stromal interaction molecule 1
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K04270  P2RY1; P2Y purinoceptor 1
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K06069  PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K17704  APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
       K06271  TLN; talin
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06493  ITGB3, CD61; integrin beta 3
       K17084  FERMT3, KIND3; kindlin 3
       K03903  FGA; fibrinogen alpha chain
       K03904  FGB; fibrinogen beta chain
       K03905  FGG; fibrinogen gamma chain
       K04298  P2RY12; P2Y purinoceptor 12
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04263  PTGIR; prostacyclin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05692  ACTB_G1; actin beta/gamma 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06236  COL1A; collagen, type I, alpha
       K19720  COL3A; collagen, type III, alpha
       K06264  GP6; platelet glycoprotein VI
       K07983  FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K06481  ITGA2, CD49b; integrin alpha 2
       K05719  ITGB1, CD29; integrin beta 1
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K03900  VWF; von Willebrand factor
       K06260  GP5, CD42d; platelet glycoprotein V
       K06261  GP1BA, CD42b; platelet glycoprotein Ib alpha chain
       K06262  GP1BB, CD42c; platelet glycoprotein Ib beta chain
       K06263  GP9, CD42a; platelet glycoprotein IX
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
       K19477  PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K01832  TBXAS1, CYP5A; thromboxane-A synthase [EC:5.3.99.5]
       K08508  SNAP23; synaptosomal-associated protein 23
       K08512  VAMP8; vesicle-associated membrane protein 8
     04620 Toll-like receptor signaling pathway [PATH:ko04620]
     04624 Toll and Imd signaling pathway [PATH:ko04624]
     04621 NOD-like receptor signaling pathway [PATH:ko04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
     04625 C-type lectin receptor signaling pathway [PATH:ko04625]
     04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
     04612 Antigen processing and presentation [PATH:ko04612]
     04660 T cell receptor signaling pathway [PATH:ko04660]
     04658 Th1 and Th2 cell differentiation [PATH:ko04658]
     04659 Th17 cell differentiation [PATH:ko04659]
     04657 IL-17 signaling pathway [PATH:ko04657]
     04662 B cell receptor signaling pathway [PATH:ko04662]
     04664 Fc epsilon RI signaling pathway [PATH:ko04664]
       K06856  IGH; immunoglobulin heavy chain
       K08089  FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
       K08090  MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
       K07983  FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K03084  SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K05430  IL4; interleukin 4
       K05435  IL13; interleukin 13
       K04736  IL3; interleukin 3
       K05428  IL5; interleukin 5
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05730  VAV; guanine nucleotide exchange factor VAV
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K07362  LAT; linker for activation of T cells
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K20735  ALOX5AP, FLAP; arachidonate 5-lipoxygenase-activating protein
     04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
       K06856  IGH; immunoglobulin heavy chain
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
       K06463  FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
       K06478  PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
       K08893  HCK; hemopoietic cell kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K12561  MARCKS; myristoylated alanine-rich C-kinase substrate
       K13536  MARCKSL1, MRP; MARCKS-related protein
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K01080  PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
       K05768  GSN; gelsolin
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04393  CDC42; cell division control protein 42
       K05747  WAS; Wiskott-Aldrich syndrome protein
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05754  ARPC5; actin related protein 2/3 complex, subunit 5
       K05755  ARPC4; actin related protein 2/3 complex, subunit 4
       K05756  ARPC3; actin related protein 2/3 complex, subunit 3
       K05757  ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
       K05758  ARPC2; actin related protein 2/3 complex, subunit 2
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K05753  WASF1; WAS protein family, member 1
       K05748  WASF2; WAS protein family, member 2
       K06083  WASF3; WAS protein family, member 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
       K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
       K05765  CFL; cofilin
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K07941  ARF6; ADP-ribosylation factor 6
       K04438  CRK, CRKII; proto-oncogene C-crk
       K12367  DOCK2; dedicator of cytokinesis protein 2
       K12488  ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
       K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
       K03084  SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K07362  LAT; linker for activation of T cells
       K23484  DNM2; dynamin 2 [EC:3.6.5.5]
       K12562  AMPH; amphiphysin
       K12559  MYO10; myosin X
     04670 Leukocyte transendothelial migration [PATH:ko04670]
     04672 Intestinal immune network for IgA production [PATH:ko04672]
     04062 Chemokine signaling pathway [PATH:ko04062]
 
   09152 Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04922 Glucagon signaling pathway [PATH:ko04922]
     04923 Regulation of lipolysis in adipocytes [PATH:ko04923]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04929 GnRH secretion [PATH:ko04929]
     04912 GnRH signaling pathway [PATH:ko04912]
       K05252  GNRH; gonadotropin-releasing hormone
       K04280  GNRHR; gonadotropin-releasing hormone receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04393  CDC42; cell division control protein 42
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K08521  LHB; lutropin subunit beta
       K08522  CGA; glycoprotein hormones alpha chain
       K05250  FSHB; follitropin subunit beta
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K07763  MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K09203  EGR1; early growth response protein 1
     04913 Ovarian steroidogenesis [PATH:ko04913]
       K08522  CGA; glycoprotein hormones alpha chain
       K08521  LHB; lutropin subunit beta
       K04248  LHCGR; lutropin-choriogonadotropic hormone receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K12473  LDLR; low-density lipoprotein receptor
       K13885  SCARB1; scavenger receptor class B, member 1
       K16931  STAR; steroidogenic acute regulatory protein, mitochondrial
       K00498  CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
       K00512  CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
       K00044  HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
       K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
       K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
       K00070  HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
       K05250  FSHB; follitropin subunit beta
       K04247  FSHR; follicle stimulating hormone receptor
       K07434  CYP19A; aromatase [EC:1.14.14.14]
       K07410  CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
       K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
       K05498  BMP15, GDF9B; bone morphogenetic protein 15
       K16620  BMP6; bone morphogenetic protein 6
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
       K05243  OXT; oxytocin-neurophysin 1
       K04229  OXTR; oxytocin receptor
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04503  CCND1; G1/S-specific cyclin-D1
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04961  RYR1; ryanodine receptor 1
       K04962  RYR2; ryanodine receptor 2
       K04963  RYR3; ryanodine receptor 3
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K04977  TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
       K04996  KCNJ2, KIR2.1; potassium inwardly-rectifying channel subfamily J member 2
       K05005  KCNJ12, KIR2.2; potassium inwardly-rectifying channel subfamily J member 12
       K04998  KCNJ4, KIR2.3; potassium inwardly-rectifying channel subfamily J member 4
       K05007  KCNJ14, KIR2.4; potassium inwardly-rectifying channel subfamily J member 14
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K18154  RGS2; regulator of G-protein signaling 2
       K17901  RCAN1, MCIP1; calcipressin-1
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K08794  CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K12334  NPPA; natriuretic peptide A
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05692  ACTB_G1; actin beta/gamma 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04997  KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
     04926 Relaxin signaling pathway [PATH:ko04926]
     04935 Growth hormone synthesis, secretion and action [PATH:ko04935]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04928 Parathyroid hormone synthesis, secretion and action [PATH:ko04928]
     04916 Melanogenesis [PATH:ko04916]
     04924 Renin secretion [PATH:ko04924]
     04614 Renin-angiotensin system [PATH:ko04614]
     04925 Aldosterone synthesis and secretion [PATH:ko04925]
     04927 Cortisol synthesis and secretion [PATH:ko04927]
 
   09153 Circulatory system
     04260 Cardiac muscle contraction [PATH:ko04260]
     04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
     04270 Vascular smooth muscle contraction [PATH:ko04270]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K09821  AGT, SERPINA8; angiotensinogen
       K04166  AGTR1; angiotensin II receptor type 1
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K04197  EDNRA; endothelin receptor type A
       K05242  AVP; arginine vasopressin
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K07425  CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
       K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12327  CALD1; caldesmon
       K12313  ACTA2; actin, aortic smooth muscle
       K12315  ACTG2; actin, gamma-enteric smooth muscle
       K12328  PPP1R14A, CPI17; protein phosphatase 1 regulatory subunit 14A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04263  PTGIR; prostacyclin receptor
       K12332  CALC; calcitonin
       K12333  ADM; adrenomedullin
       K04577  CALCRL; calcitonin receptor-like
       K08447  RAMP1; receptor activity modifying protein 1
       K08448  RAMP2; receptor activity modifying protein 2
       K08449  RAMP3; receptor activity modifying protein 3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12334  NPPA; natriuretic peptide A
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12336  NPPC; natriuretic peptide C
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
     04724 Glutamatergic synapse [PATH:ko04724]
       K14990  SLC38A1, SNAT1, GLNT; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1
       K14207  SLC38A2, SNAT2; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2
       K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
       K12302  SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
       K05201  GRIK1; glutamate receptor, ionotropic kainate 1
       K05202  GRIK2; glutamate receptor, ionotropic kainate 2
       K05203  GRIK3; glutamate receptor, ionotropic kainate 3
       K05204  GRIK4; glutamate receptor, ionotropic kainate 4
       K05205  GRIK5; glutamate receptor, ionotropic kainate 5
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K05213  GRIN3A; glutamate receptor ionotropic, NMDA 3A
       K05214  GRIN3B; glutamate receptor ionotropic, NMDA 3B
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K11828  DLG4, PSD95; discs large protein 4
       K15008  DLGAP1, GKAP; discs, large-associated protein 1
       K15009  SHANK; SH3 and multiple ankyrin repeat domains protein
       K04964  TRPC1; transient receptor potential cation channel subfamily C member 1
       K04603  GRM1; metabotropic glutamate receptor 1
       K04604  GRM5; metabotropic glutamate receptor 5
       K15010  HOMER; homer
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04605  GRM2; metabotropic glutamate receptor 2
       K04606  GRM3; metabotropic glutamate receptor 3
       K04607  GRM4; metabotropic glutamate receptor 4
       K04608  GRM6; metabotropic glutamate receptor 6
       K04609  GRM7; metabotropic glutamate receptor 7
       K04610  GRM8; metabotropic glutamate receptor 8
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K00910  ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
       K04997  KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
       K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
       K05613  SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
       K05618  SLC1A7, EAAT5; solute carrier family 1 (glutamate transporter), member 7
       K05612  SLC1A1, EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1
       K05617  SLC1A6, EAAT4; solute carrier family 1 (high affinity glutamate/aspartate transporter), member 6
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K05614  SLC1A3, EAAT1; solute carrier family 1 (glial high affinity glutamate transporter), member 3
       K01915  glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
       K13576  SLC38A3, SNAT3; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3
     04727 GABAergic synapse [PATH:ko04727]
     04725 Cholinergic synapse [PATH:ko04725]
     04728 Dopaminergic synapse [PATH:ko04728]
     04726 Serotonergic synapse [PATH:ko04726]
       K00502  TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
       K01593  DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
       K08155  SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K17718  CYP2C8; cytochrome P450 family 2 subfamily C polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
       K17720  CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
       K17721  CYP2C19; cytochrome P450 family 2 subfamily C polypeptide 19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
       K07413  CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
       K17712  CYP2D6; cytochrome P450 family 2 subfamily D polypeptide 6 [EC:1.14.14.1]
       K07414  CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
       K07428  CYP4X; cytochrome P450 family 4 subfamily X [EC:1.14.14.1]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K08021  ALOX12B; arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
       K08022  ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04819  HTR3; 5-hydroxytryptamine receptor 3
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04943  KCNN2, KCA2.2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
       K04892  KCND2, KV4.2; potassium voltage-gated channel Shal-related subfamily D member 2
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04520  APP; amyloid beta A4 protein
       K04153  HTR1; 5-hydroxytryptamine receptor 1
       K04161  HTR5; 5-hydroxytryptamine receptor 5
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K21278  DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
       K04997  KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
       K04964  TRPC1; transient receptor potential cation channel subfamily C member 1
       K05037  SLC6A4, SERT; solute carrier family 6 (neurotransmitter transporter, serotonin) member 4
       K00274  MAO, aofH; monoamine oxidase [EC:1.4.3.4]
     04720 Long-term potentiation [PATH:ko04720]
     04730 Long-term depression [PATH:ko04730]
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
       K19477  PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
       K08067  PPP1R17, GSBS; protein phosphatase 1 regulatory subunit 17
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05207  GRID2; glutamate receptor delta-2 subunit
       K04603  GRM1; metabotropic glutamate receptor 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04535  GNAZ; guanine nucleotide-binding protein G(z) subunit alpha
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04961  RYR1; ryanodine receptor 1
       K05256  CRH; corticotropin-releasing hormone
       K04578  CRHR1; corticotropin releasing hormone receptor 1
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
     04723 Retrograde endocannabinoid signaling [PATH:ko04723]
     04721 Synaptic vesicle cycle [PATH:ko04721]
     04722 Neurotrophin signaling pathway [PATH:ko04722]
 
   09157 Sensory system
     04744 Phototransduction [PATH:ko04744]
     04745 Phototransduction - fly [PATH:ko04745]
     04740 Olfactory transduction [PATH:ko04740]
     04742 Taste transduction [PATH:ko04742]
     04750 Inflammatory mediator regulation of TRP channels [PATH:ko04750]
       K03898  KNG, BK; kininogen
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04149  HRH1; histamine receptor H1
       K04269  P2RY2; P2Y purinoceptor 2
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K04984  TRPA1, ANKTM1; transient receptor potential cation channel subfamily A member 1
       K05222  TRPV1; transient receptor potential cation channel subfamily V member 1
       K04829  ASIC1, ACCN2, BNAC2; acid-sensing ion channel 1
       K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
       K04830  ASIC3, ACCN3; acid-sensing ion channel 3
       K04831  ASIC4, ACCN4, BNAC4; acid-sensing ion channel 4
       K04832  ASIC5, ACCN5; acid-sensing ion channel 5
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1, CD121a; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04983  TRPM8; transient receptor potential cation channel subfamily M member 8
       K04259  PTGER2; prostaglandin E receptor 2
       K04261  PTGER4; prostaglandin E receptor 4
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04973  TRPV4; transient receptor potential cation channel subfamily V member 4
       K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
       K07413  CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
       K07425  CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K05459  IGF1; insulin-like growth factor 1
       K04971  TRPV2; transient receptor potential cation channel subfamily V member 2
       K04972  TRPV3; transient receptor potential cation channel subfamily V member 3
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:ko05200]
     05202 Transcriptional misregulation in cancer [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
     05230 Central carbon metabolism in cancer [PATH:ko05230]
     05231 Choline metabolism in cancer [PATH:ko05231]
       K04357  EGF; epidermal growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K05747  WAS; Wiskott-Aldrich syndrome protein
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K05753  WASF1; WAS protein family, member 1
       K05748  WASF2; WAS protein family, member 2
       K06083  WASF3; WAS protein family, member 3
       K04684  SP1; transcription factor Sp1
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K14387  SLC5A7, CHT1; solute carrier family 5 (high affinity choline transporter), member 7
       K06515  SLC44A1, CD92; solute carrier family 44 (choline transporter-like protein), member 1
       K15377  SLC44A2_4_5; solute carrier family 44 (choline transporter-like protein), member 2/4/5
       K15282  SLC44A3; solute carrier family 44 (choline transporter-like protein), member 3
       K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
       K08199  SLC22A2, OCT2; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
       K08200  SLC22A3, OCT3; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
       K08202  SLC22A4_5, OCTN; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5
       K14156  CHK; choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K00968  PCYT1; choline-phosphate cytidylyltransferase [EC:2.7.7.15]
       K00994  CHPT1, CPT1; diacylglycerol cholinephosphotransferase [EC:2.7.8.2]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K01080  PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
       K00901  dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K06128  LYPLA1; lysophospholipase I [EC:3.1.1.5]
       K18695  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
 
   09162 Cancer: specific types
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 12, 2019