K01495  GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16]
       K09007  folE2; GTP cyclohydrolase IB [EC:3.5.4.16]
       K22391  E3.5.4.16; GTP cyclohydrolase I [EC:3.5.4.16]
       K01077  E3.1.3.1, phoA, phoB; alkaline phosphatase [EC:3.1.3.1]
       K01113  phoD; alkaline phosphatase D [EC:3.1.3.1]
       K08310  nudB, ntpA; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]
       K19965  folQ; dihydroneopterin triphosphate pyrophosphohydrolase [EC:3.6.1.67]
       K13939  FOL1; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
       K13940  sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3]
       K01633  folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
       K00950  folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
       K00796  folP; dihydropteroate synthase [EC:2.5.1.15]
       K13941  folKP; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
       K24102  folCP; dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
       K18974  sul1; dihydropteroate synthase type 1 [EC:2.5.1.15]
       K18824  sul2; dihydropteroate synthase type 2 [EC:2.5.1.15]
       K18825  sul3; dihydropteroate synthase type 3 [EC:2.5.1.15]
       K00287  DHFR, folA; dihydrofolate reductase [EC:1.5.1.3]
       K18589  dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19643  dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K18590  dfrA12, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19644  dfrA19, dfrA18; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19645  dfrB, dfr2; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K18591  dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K13998  DHFR-TS; dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
       K01930  FPGS; folylpolyglutamate synthase [EC:6.3.2.17]
       K11754  folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
       K22099  folC2; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
       K20457  DHFS; dihydrofolate synthase [EC:6.3.2.12]
       K01307  GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
       K01497  ribA, RIB1; GTP cyclohydrolase II [EC:3.5.4.25]
       K14652  ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
       K22100  trpF; 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase [EC:4.2.1.160]
       K22101  PTPS; dihydroneopterin triphosphate aldolase (PTPS-III) / 6-pyruvoyltetrahydropterin synthase [EC:4.1.2.60 4.2.3.12]
       K01664  pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85]
       K01665  pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]
       K13950  pabAB; para-aminobenzoate synthetase [EC:2.6.1.85]
       K03342  pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
       K25575  pabA; 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) component II [EC:2.6.1.123]
       K25578  pabB; 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) component I [EC:2.6.1.123]
       K02619  pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
       K18482  ADCL; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
       K07589  folX; D-erythro-7,8-dihydroneopterin triphosphate epimerase [EC:5.1.99.7]
       K13938  folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
       K01737  queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
       K00072  SPR; sepiapterin reductase [EC:1.1.1.153]
       K00011  AKR1B; aldehyde reductase [EC:1.1.1.21]
       K00079  CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
       K00357  QDPR; dihydropteridine reductase [EC:1.5.1.34]
       K01724  PCBD, phhB; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
       K00500  phhA, PAH; phenylalanine-4-hydroxylase [EC:1.14.16.1]
       K00501  TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
       K00502  TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
       K03793  PTR1; pteridine reductase [EC:1.5.1.33]
       K17745  spr1; sepiapterin reductase [EC:1.1.1.325]
       K00310  SE; pyrimidodiazepine synthase [EC:1.5.4.1]
       K10026  queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
       K06920  queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
       K06879  queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
       K09457  queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
       K17488  mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
       K17487  mptB; 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase [EC:3.1.4.56]
       K09739  mptD; dihydroneopterin aldolase [EC:4.1.2.25]
       K07142  mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
       K06984  K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
       K06897  K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
       K17364  dmrA; dihydromethanopterin reductase [EC:1.5.1.47]
       K18853  dmrX; dihydromethanopterin reductase (acceptor) [EC:1.5.99.15]
       K15740  mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33]
       K22102  E4.1.2.59; dihydroneopterin phosphate aldolase [EC:4.1.2.59]
       K03639  moaA, CNX2; GTP 3',8-cyclase [EC:4.1.99.22]
       K03637  moaC, CNX3; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
       K20967  MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase [EC:4.1.99.22 4.6.1.17]
       K03635  MOCS2B, moaE; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
       K21142  moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]
       K03831  mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
       K03638  moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
       K03750  moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
       K15376  GPHN; gephyrin [EC:2.10.1.1 2.7.7.75]
       K07141  mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
       K03752  mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
       K13818  mobAB; molybdopterin-guanine dinucleotide biosynthesis protein [EC:2.7.7.77]
       K15631  ABA3; molybdenum cofactor sulfurtransferase [EC:2.8.1.9]

       K00287  DHFR, folA; dihydrofolate reductase [EC:1.5.1.3]
       K18589  dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19643  dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K18590  dfrA12, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19644  dfrA19, dfrA18; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19645  dfrB, dfr2; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K18591  dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K13998  DHFR-TS; dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
       K13938  folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
       K01938  fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
       K13402  MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
       K00288  MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
       K01491  folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
       K01500  fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]
       K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+) [EC:1.5.1.5 1.5.1.-]
       K13403  MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
       K00295  MTD1; methylenetetrahydrofolate dehydrogenase (NAD+) [EC:1.5.1.15]
       K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
       K11787  GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
       K00601  E2.1.2.2; phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
       K11175  purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
       K01492  purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
       K00602  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
       K00603  fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
       K13990  FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]
       K00604  MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9]
       K00605  gcvT, AMT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
       K00548  metH, MTR; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
       K24042  yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
       K25221  mtgA; [methyl-Co(III) glycine betaine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.378]
       K25915  mtvA; [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.385]
       K26930  mtqA; [methyl-Co(III) quaternary-amine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.389]
       K00560  thyA, TYMS; thymidylate synthase [EC:2.1.1.45]
       K03465  thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148]
       K00289  ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
       K01433  purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
       K25009  E1.5.1.20; methylenetetrahydrofolate reductase [NAD(P)H] [EC:1.5.1.20]
       K25004  MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
       K00297  metF, MTHFR; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
       K25007  metV; methylenetetrahydrofolate reductase (NADH) small subunit
       K25008  rnfC2; ion-translocating oxidoreductase complex subunit C [EC:7.-.-.-]
       K01746  E4.3.1.4; formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4]
       K01934  MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]

       K18698  blaTEM; beta-lactamase class A TEM [EC:3.5.2.6]
       K18699  blaSHV; beta-lactamase class A SHV [EC:3.5.2.6]
       K18796  blaLEN; beta-lactamase class A LEN [EC:3.5.2.6]
       K18767  blaCTX-M; beta-lactamase class A CTX-M [EC:3.5.2.6]
       K18797  blaPER; beta-lactamase class A PER [EC:3.5.2.6]
       K19097  blaVEB; beta-lactamase class A VEB [EC:3.5.2.6]
       K19317  blaBEL; beta-lactamase class A BEL [EC:3.5.2.6]
       K18768  blaKPC; beta-lactamase class A KPC [EC:3.5.2.6]
       K18970  blaGES; beta-lactamase class A GES [EC:3.5.2.6]
       K19316  blaIMI; beta-lactamase class A IMI [EC:3.5.2.6]
       K22346  blaSME; beta-lactamase class A SME [EC:3.5.2.6]
       K18795  blaCARB-1; beta-lactamase class A CARB-1, PSE family [EC:3.5.2.6]
       K19218  blaCARB-5; beta-lactamase class A CARB-5, RTG family [EC:3.5.2.6]
       K19217  blaCARB-17; beta-lactamase class A CARB-17 [EC:3.5.2.6]
       K18790  blaOXA-1; beta-lactamase class D OXA-1 [EC:3.5.2.6]
       K18791  blaOXA-2; beta-lactamase class D OXA-2 [EC:3.5.2.6]
       K19098  blaOXA-9; beta-lactamase class D OXA-9 [EC:3.5.2.6]
       K18792  blaOXA-10; beta-lactamase class D OXA-10 [EC:3.5.2.6]
       K19213  blaOXA-12; beta-lactamase class D OXA-12 [EC:3.5.2.6]
       K21276  blaOXA-22; beta-lactamase class D OXA-22 [EC:3.5.2.6]
       K18793  blaOXA-23; beta-lactamase class D OXA-23 [EC:3.5.2.6]
       K18971  blaOXA-24; beta-lactamase class D OXA-24 [EC:3.5.2.6]
       K22352  blaOXA-29; beta-lactamase class D OXA-29 [EC:3.5.2.6]
       K19209  blaOXA-42; beta-lactamase class D OXA-42 [EC:3.5.2.6]
       K18976  blaOXA-48; beta-lactamase class D OXA-48 [EC:3.5.2.6]
       K18973  blaOXA-50; beta-lactamase class D OXA-50 [EC:3.5.2.6]
       K18794  blaOXA-51; beta-lactamase class D OXA-51 [EC:3.5.2.6]
       K18972  blaOXA-58; beta-lactamase class D OXA-58 [EC:3.5.2.6]
       K21277  blaOXA-60; beta-lactamase class D OXA-60 [EC:3.5.2.6]
       K19210  blaOXA-61; beta-lactamase class D OXA-61 [EC:3.5.2.6]
       K19211  blaOXA-62; beta-lactamase class D OXA-62 [EC:3.5.2.6]
       K19212  blaOXA-63; beta-lactamase class D OXA-63 [EC:3.5.2.6]
       K22335  blaOXA-114; beta-lactamase class D OXA-114 [EC:3.5.2.6]
       K19319  blaOXA-134; beta-lactamase class D OXA-134 [EC:3.5.2.6]
       K22331  blaOXA-184; beta-lactamase class D OXA-184 [EC:3.5.2.6]
       K22351  blaOXA-209; beta-lactamase class D OXA-209 [EC:3.5.2.6]
       K19320  blaOXA-211; beta-lactamase class D OXA-211 [EC:3.5.2.6]
       K19318  blaOXA-213; beta-lactamase class D OXA-213 [EC:3.5.2.6]
       K19321  blaOXA-214; beta-lactamase class D OXA-214 [EC:3.5.2.6]
       K19322  blaOXA-229; beta-lactamase class D OXA-229 [EC:3.5.2.6]
       K21266  blaOXA-286; beta-lactamase class D OXA-286 [EC:3.5.2.6]
       K22334  blaOXA-464; beta-lactamase class D OXA-464 [EC:3.5.2.6]
       K22333  blaOXA-493; beta-lactamase class D OXA-493 [EC:3.5.2.6]
       K22332  blaOXA-548; beta-lactamase class D OXA-548 [EC:3.5.2.6]
       K19095  blaCMY-1; beta-lactamase class C CMY-1 [EC:3.5.2.6]
       K19096  blaCMY-2; beta-lactamase class C CMY-2 [EC:3.5.2.6]
       K19100  blaDHA; beta-lactamase class C DHA [EC:3.5.2.6]
       K19101  blaFOX; beta-lactamase class C FOX [EC:3.5.2.6]
       K19214  blaACC; beta-lactamase class C ACC [EC:3.5.2.6]
       K19215  blaACT_MIR; beta-lactamase class C ACT/MIR [EC:3.5.2.6]
       K20319  blaADC; beta-lactamase class C ADC [EC:3.5.2.6]
       K20320  blaPDC; beta-lactamase class C PDC [EC:3.5.2.6]
       K18782  blaIMP; metallo-beta-lactamase class B IMP [EC:3.5.2.6]
       K18781  blaVIM; metallo-beta-lactamase class B VIM [EC:3.5.2.6]
       K18780  blaNDM; metallo-beta-lactamase class B NDM [EC:3.5.2.6]
       K19099  blaGIM; metallo-beta-lactamase class B GIM [EC:3.5.2.6]
       K19216  blaIND; metallo-beta-lactamase class B IND [EC:3.5.2.6]
       K17840  aac2-I; aminoglycoside 2'-N-acetyltransferase I [EC:2.3.1.59]
       K03395  aac3-I; aminoglycoside 3-N-acetyltransferase I [EC:2.3.1.60]
       K19275  aac3-II; aminoglycoside 3-N-acetyltransferase II [EC:2.3.1.81]
       K19276  aac3-IV; aminoglycoside 3-N-acetyltransferase IV [EC:2.3.1.81]
       K19277  aac3-VI; aminoglycoside 3-N-acetyltransferase VI [EC:2.3.1.81]
       K00662  aacC; aminoglycoside 3-N-acetyltransferase [EC:2.3.1.81]
       K18815  aac6-I; aminoglycoside 6'-N-acetyltransferase I [EC:2.3.1.82]
       K19278  aac6-Ib; aminoglycoside 6'-N-acetyltransferase Ib [EC:2.3.1.82]
       K18816  aac6-I, aacA7; aminoglycoside 6'-N-acetyltransferase I [EC:2.3.1.82]
       K19301  aac6-II; aminoglycoside 6'-N-acetyltransferase II [EC:2.3.1.82]
       K00663  aacA; aminoglycoside 6'-N-acetyltransferase [EC:2.3.1.82]
       K19883  aacA-aphD; bifunctional aminoglycoside 6'-N-acetyltransferase / aminoglycoside 2''-phosphotransferase [EC:2.3.1.82 2.7.1.190]
       K19313  apmA; aminocyclitol acetyltransferase [EC:2.3.-.-]
       K19063  sat2; streptothricin acetyltransferase [EC:2.3.-.-]
       K19314  sat3; streptothricin acetyltransferase [EC:2.3.-.-]
       K19273  sat4; streptothricin acetyltransferase [EC:2.3.-.-]
       K17881  aadB; aminoglycoside 2''-adenylyltransferase [EC:2.7.7.46]
       K00984  aadA; streptomycin 3"-adenylyltransferase [EC:2.7.7.47]
       K17882  aadD, knt; kanamycin nucleotidyltransferase [EC:2.7.7.-]
       K19544  ant4-II; aminoglycoside 4'-adenylyltransferase [EC:2.7.7.-]
       K05593  aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-]
       K19279  ant9; aminoglycoside 9-adenylyltransferase [EC:2.7.7.-]
       K17910  aphD; aminoglycoside 2''-phosphotransferase [EC:2.7.1.190]
       K19272  aph3-I; aminoglycoside 3'-phosphotransferase I [EC:2.7.1.95]
       K19300  aph3-II; aminoglycoside 3'-phosphotransferase II [EC:2.7.1.95]
       K19299  aph3-III; aminoglycoside 3'-phosphotransferase III [EC:2.7.1.95]
       K19274  aph3-VI; aminoglycoside 3'-phosphotransferase VI [EC:2.7.1.95]
       K19543  aph3-VII; aminoglycoside 3'-phosphotransferase [EC:2.7.1.95]
       K19315  aph3-XV; aminoglycoside 3'-phosphotransferase XV [EC:2.7.1.95]
       K00897  aphA; kanamycin kinase [EC:2.7.1.95]
       K10673  strA; streptomycin 3"-kinase [EC:2.7.1.87]
       K18817  hph; hygromycin-B 4-O-kinase [EC:2.7.1.163]
       K12570  aphD, strA; streptomycin 6-kinase [EC:2.7.1.72]
       K04343  strB; streptomycin 6-kinase [EC:2.7.1.72]
       K17880  hyg; hygromycin-B 7''-O-kinase [EC:2.7.1.119]
       K18844  aph, spcN; spectinomycin phosphotransferase
       K18845  rmt, armA; 16S rRNA (guanine(1405)-N(7))-methyltransferase [EC:2.1.1.179]
       K18846  npmA; 16S rRNA (adenine(1408)-N(1))-methyltransferase [EC:2.1.1.180]
       K08151  tetA; MFS transporter, DHA1 family, tetracycline resistance protein
       K08168  tetB; MFS transporter, DHA2 family, metal-tetracycline-proton antiporter
       K18214  tetP_A, tet40; MFS transporter, DHA3 family, tetracycline resistance protein
       K18215  tetV; MFS transporter, DHA3 family, tetracycline resistance protein
       K18218  tet35; tetracycline resistance efflux pump
       K18216  steA, tetA46; ATP-binding cassette, subfamily B, tetracycline resistant protein
       K18217  steB, tetB46; ATP-binding cassette, subfamily B, tetracycline resistant protein
       K19542  otrB, tcr; MFS transporter, DHA2 family, tetracycline/oxytetracycline resistance protein
       K18233  oleC5; oleandomycin transport system permease protein
       K18220  tetM, tetO; ribosomal protection tetracycline resistance protein
       K18221  tetX; tetracycline 11a-monooxygenase, tetracycline resistance protein [EC:1.14.13.231]
       K00561  ermC, ermA; 23S rRNA (adenine-N6)-dimethyltransferase [EC:2.1.1.184]
       K14336  rlmA2; 23S rRNA (guanine748-N1)-methyltransferase [EC:2.1.1.188]
       K15632  cfr; 23S rRNA (adenine-C8)-methyltransferase [EC:2.1.1.224]
       K18230  tylC, oleB, carA, srmB; macrolide transport system ATP-binding/permease protein
       K18231  msr, vmlR; macrolide transport system ATP-binding/permease protein
       K19349  vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
       K19350  lsa; lincosamide and streptogramin A transport system ATP-binding/permease protein
       K18232  oleC4; oleandomycin transport system ATP-binding protein
       K19541  lmrA; MFS transporter, DHA2 family, lincomycin resistance protein
       K08217  mef; MFS transporter, DHA3 family, macrolide efflux protein
       K18833  cmr; MFS transporter, DHA3 family, multidrug efflux protein
       K08160  mdfA, cmr; MFS transporter, DHA1 family, multidrug/chloramphenicol efflux transport protein
       K06880  ereA_B; erythromycin esterase [EC:3.1.1.-]
       K18235  vgb; virginiamycin B lyase [EC:4.2.99.-]
       K19545  lnuA_C_D_E, lin; lincosamide nucleotidyltransferase A/C/D/E
       K18236  lnuB_F, lin; lincosamide nucleotidyltransferase B/F
       K18234  vat; virginiamycin A acetyltransferase [EC:2.3.1.-]
       K21251  mgt, oleD; macrolide glycosyltransferase
       K06979  mph; macrolide phosphotransferase
       K18552  cmlA, cmlB, floR; MFS transporter, DHA1 family, chloramphenicol/florfenicol resistance protein
       K18553  cmlR, cmx; MFS transporter, DHA1 family, chloramphenicol resistance protein
       K19646  fexA_B; MFS transporter, DHA2 family, florfenicol/chloramphenicol resistance protein
       K19271  catA; chloramphenicol O-acetyltransferase type A [EC:2.3.1.28]
       K00638  catB; chloramphenicol O-acetyltransferase type B [EC:2.3.1.28]
       K18554  cpt; chloramphenicol 3-O phosphotransferase [EC:2.7.1.-]
       K18974  sul1; dihydropteroate synthase type 1 [EC:2.5.1.15]
       K18824  sul2; dihydropteroate synthase type 2 [EC:2.5.1.15]
       K18825  sul3; dihydropteroate synthase type 3 [EC:2.5.1.15]
       K18589  dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19643  dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K18590  dfrA12, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19644  dfrA19, dfrA18; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K18591  dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K19645  dfrB, dfr2; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
       K08167  smvA, qacA, lfrA; MFS transporter, DHA2 family, multidrug resistance protein
       K18555  qnr, mcbG; fluoroquinolone resistance protein
       K19062  arr; rifampin ADP-ribosylating transferase
       K21288  arr2; rifampin ADP-ribosylating transferase
       K21267  iri, rox; rifampicin monooxygenase [EC:1.14.13.211]
       K21253  fosA; glutathione S-transferase fosA [EC:2.5.1.18]
       K21264  fosA2; glutathione S-transferase fosA2 [EC:2.5.1.18]
       K21265  fosA5; glutathione S-transferase fosA5 [EC:2.5.1.18]
       K21252  fosX; fosfomycin resistance protein FosX
       K02547  mecR1; methicillin resistance protein
       K02546  mecI; BlaI family transcriptional regulator, methicillin resistance regulatory protein
       K02545  mecA; penicillin-binding protein 2 prime [EC:3.4.16.4]
       K02172  blaR1; bla regulator protein blaR1
       K02171  blaI; BlaI family transcriptional regulator, penicillinase repressor
       K18766  blaZ; beta-lactamase class A BlaZ [EC:3.5.2.6]
       K17836  penP; beta-lactamase class A [EC:3.5.2.6]
       K18072  parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
       K18073  parR; two-component system, OmpR family, response regulator ParR
       K07644  cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
       K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
       K18297  mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
       K18093  oprD; imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-]
       K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
       K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
       K07260  vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
       K18346  vanW; vancomycin resistance protein VanW
       K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
       K18352  vanRAc; two-component system, OmpR family, response regulator VanR
       K18354  vanK; vancomycin resistance protein VanK
       K18353  vanJ; vancomycin resistance protein VanJ
       K18347  vanH; D-specific alpha-keto acid dehydrogenase [EC:1.1.1.-]
       K15739  vanB, vanA, vanD; D-alanine---(R)-lactate ligase [EC:6.1.2.1]
       K08641  vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
       K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
       K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
       K18348  vanT; serine/alanine racemase [EC:5.1.1.18 5.1.1.1]
       K18856  vanC, vanE, vanG; D-alanine---D-serine ligase [EC:6.3.2.35]
       K18866  vanXY; zinc D-Ala-D-Ala dipeptidase/carboxypeptidase [EC:3.4.13.22 3.4.17.14]
       K18906  mgrA; MarR family transcriptional regulator, multiple gene regulator MgrA
       K19077  graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3]
       K19078  graR; two-component system, OmpR family, response regulator protein GraR
       K03367  dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
       K03739  dltB; membrane protein involved in D-alanine export
       K14188  dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
       K03740  dltD; D-alanine transfer protein
       K14205  mprF, fmtC; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
       K19079  vraF; cationic antimicrobial peptide transport system ATP-binding protein
       K19080  vraG; cationic antimicrobial peptide transport system permease protein
       K07637  phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
       K07660  phoP; two-component system, OmpR family, response regulator PhoP
       K08477  pgtE; outer membrane protease E [EC:3.4.21.-]
       K18131  mexR; MarR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon
       K03585  acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system
       K18138  acrB, mexB, adeJ, smeE, mtrD, cmeB; multidrug efflux pump
       K18139  oprM, emhC, ttgC, cusC, adeK, smeF, mtrE, cmeC, gesC; outer membrane protein, multidrug efflux system
       K18294  nfxB; TetR/AcrR family transcriptional regulator, mexCD-oprJ operon repressor
       K18295  mexC; membrane fusion protein, multidrug efflux system
       K18296  mexD; multidrug efflux pump
       K18298  mexE; membrane fusion protein, multidrug efflux system
       K18299  mexF; multidrug efflux pump
       K18300  oprN; outer membrane protein, multidrug efflux system
       K18301  mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
       K18302  mexJ; membrane fusion protein, multidrug efflux system
       K18303  mexK; multidrug efflux pump
       K18129  mexZ; TetR/AcrR family transcriptional regulator, mexXY operon repressor
       K18094  mexX, amrA; membrane fusion protein, multidrug efflux system
       K18095  mexY, amrB; multidrug efflux pump
       K18304  lasR; LuxR family transcriptional regulator, quorum-sensing system regulator LasR
       K19591  cueR; MerR family transcriptional regulator, copper efflux regulator
       K19595  gesA, mexP; membrane fusion protein, gold/copper resistance efflux system
       K19594  gesB, mexQ; gold/copper resistance efflux pump
       K19593  opmE; outer membrane protein, multidrug efflux system
       K18143  adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
       K18144  adeR; two-component system, OmpR family, response regulator AdeR
       K18145  adeA; membrane fusion protein, multidrug efflux system
       K18146  adeB; multidrug efflux pump
       K18147  adeC; outer membrane protein, multidrug efflux system
       K18140  envR, acrS; TetR/AcrR family transcriptional regulator, acrEF/envCD operon repressor
       K18141  acrE; membrane fusion protein, multidrug efflux system
       K18142  acrF; multidrug efflux pump
       K12340  tolC, bepC, cyaE, raxC, sapF, rsaF, hasF; outer membrane protein
       K07690  evgA, bvgA; two-component system, NarL family, response regulator EvgA
       K18898  mdtE; membrane fusion protein, multidrug efflux system
       K18899  mdtF; multidrug efflux pump
       K18900  bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC
       K18901  bpeE; membrane fusion protein, multidrug efflux system
       K18902  bpeF; multidrug efflux pump
       K18903  oprC, opcM; outer membrane protein, multidrug efflux system
       K18907  norG; GntR family transcriptional regulator, regulator for abcA and norABC
       K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2]
       K08170  norB, norC; MFS transporter, DHA2 family, multidrug resistance protein
       K18938  qacR; TetR/AcrR family transcriptional regulator, repressor for qacA
       K18909  mepR; MarR family transcriptional regulator, repressor for mepA
       K18908  mepA; MATE family, multidrug efflux pump
       K13632  marA; AraC family transcriptional regulator, mar-sox-rob regulon activator
       K18513  micF; small regulatory RNA MicF
       K09476  ompF; outer membrane pore protein F