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 1. Oxidoreductases
   1.1  Acting on the CH-OH group of donors
   1.2  Acting on the aldehyde or oxo group of donors
   1.3  Acting on the CH-CH group of donors
   1.4  Acting on the CH-NH2 group of donors
   1.5  Acting on the CH-NH group of donors
   1.6  Acting on NADH or NADPH
   1.7  Acting on other nitrogenous compounds as donors
   1.8  Acting on a sulfur group of donors
   1.9  Acting on a heme group of donors
   1.10  Acting on diphenols and related substances as donors
   1.11  Acting on a peroxide as acceptor
   1.12  Acting on hydrogen as donor
   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
     1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
     1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
     1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor  salicylate 1-monooxygenase  4-hydroxybenzoate 3-monooxygenase  melilotate 3-monooxygenase  imidazoleacetate 4-monooxygenase  orcinol 2-monooxygenase  phenol 2-monooxygenase (NADPH)  flavin-containing monooxygenase  kynurenine 3-monooxygenase  2,6-dihydroxypyridine 3-monooxygenase  trans-cinnamate 2-monooxygenase  cyclopentanone monooxygenase  4-hydroxyphenylacetate 1-monooxygenase  taxifolin 8-monooxygenase  2,4-dichlorophenol 6-monooxygenase  cyclohexanone monooxygenase  3-hydroxybenzoate 4-monooxygenase  3-hydroxybenzoate 6-monooxygenase  methane monooxygenase (soluble)  4-aminobenzoate 1-monooxygenase  4-nitrophenol 2-monooxygenase  2-nitrophenol 2-monooxygenase  albendazole monooxygenase  4-hydroxybenzoate 3-monooxygenase [NAD(P)H]  leukotriene-E4 20-monooxygenase  anthranilate 3-monooxygenase (deaminating)  anhydrotetracycline 6-monooxygenase  nitric-oxide synthase (NADPH)  anthraniloyl-CoA monooxygenase  questin monooxygenase  2-hydroxybiphenyl 3-monooxygenase  (-)-menthol monooxygenase  pentachlorophenol monooxygenase  6-oxocineole dehydrogenase  ketosteroid monooxygenase  benzoyl-CoA 3-monooxygenase  L-lysine N6-monooxygenase (NADPH)  2-hydroxyquinoline 8-monooxygenase  4-hydroxyquinoline 3-monooxygenase  3-hydroxyphenylacetate 6-hydroxylase  4-hydroxybenzoate 1-hydroxylase  2-hydroxycyclohexanone 2-monooxygenase  alkene monooxygenase  magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase  vanillate monooxygenase  precorrin-3B synthase  4-hydroxyacetophenone monooxygenase  phenylacetone monooxygenase  senecionine N-oxygenase  monocyclic monoterpene ketone monooxygenase  epi-isozizaene 5-monooxygenase  limonene 1,2-monooxygenase  methanesulfonate monooxygenase (NADH)  FAD-dependent urate hydroxylase  6-hydroxynicotinate 3-monooxygenase  chlorophyllide-a oxygenase  3-(3-hydroxyphenyl)propanoate hydroxylase  7-methylxanthine demethylase  pyrrole-2-carboxylate monooxygenase  dissimilatory dimethyl sulfide monooxygenase  1-hydroxy-2-naphthoate hydroxylase  taxoid 14beta-hydroxylase  taxoid 7beta-hydroxylase  trimethylamine monooxygenase  phenylacetyl-CoA 1,2-epoxidase  (+)-sabinene 3-hydroxylase  erythromycin 12-hydroxylase  alpha-pinene monooxygenase  (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase  (+)-camphor 6-exo-hydroxylase  6-hydroxy-3-succinoylpyridine 3-monooxygenase  4-nitrocatechol 4-monooxygenase  4-nitrophenol 4-monooxygenase  indole-3-pyruvate monooxygenase  pentalenolactone D synthase  neopentalenolactone D synthase  salicylate 5-hydroxylase  methylxanthine N1-demethylase  methylxanthine N3-demethylase  aklavinone 12-hydroxylase  13-deoxydaunorubicin hydroxylase  2-heptyl-3-hydroxy-4(1H)-quinolone synthase  L-evernosamine nitrososynthase  5-methyl-1-naphthoate 3-hydroxylase  L-ornithine N5-monooxygenase (NADPH)  L-ornithine N5-monooxygenase [NAD(P)H]  tetracenomycin A2 monooxygenase-dioxygenase  benzoyl-CoA 2,3-epoxidase  salicyloyl-CoA 5-hydroxylase  4-methyl-5-nitrocatechol 5-monooxygenase  rifampicin monooxygenase  1,3,7-trimethyluric acid 5-monooxygenase  protoasukamycin 4-monooxygenase  asperlicin C monooxygenase  protodeoxyviolaceinate monooxygenase  5-methylphenazine-1-carboxylate 1-monooxygenase  resorcinol 4-hydroxylase (NADPH)  resorcinol 4-hydroxylase (NADH)  aurachin C monooxygenase/isomerase  3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase  violacein synthase  F-actin monooxygenase  acetone monooxygenase (methyl acetate-forming)  propane 2-monooxygenase  jasmonic acid 12-hydroxylase  tert-butyl alcohol monooxygenase  butane monooxygenase (soluble)  tetracycline 11a-monooxygenase  6-methylpretetramide 4-monooxygenase  4-hydroxy-6-methylpretetramide 12a-monooxygenase  5a,11a-dehydrotetracycline 5-monooxygenase  indole-3-acetate monooxygenase  toluene 4-monooxygenase  aliphatic glucosinolate S-oxygenase  dimethylamine monooxygenase  carnitine monooxygenase  2-polyprenylphenol 6-hydroxylase  5-pyridoxate monooxygenase  3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase  toluene 2-monooxygenase  phenol 2-monooxygenase (NADH)  assimilatory dimethylsulfide S-monooxygenase  4beta-methylsterol monooxygenase  stachydrine N-demethylase
         K02294  crtR; beta-carotene hydroxylase [EC:1.14.13.-]
         K03185  ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
         K06126  COQ6; ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-]
         K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
         K09587  CYP90B1, DWF4; steroid 22-alpha-hydroxylase [EC:1.14.13.-]
         K10215  ethA; monooxygenase [EC:1.14.13.-]
         K12639  CYP724B1, D11; cytochrome P450 family 724 subfamily B polypeptide 1 [EC:1.14.13.-]
         K13267  CYP71D9, F6H; flavonoid 6-hydroxylase [EC:1.14.13.-]
         K15060  ligXa; 5,5'-dehydrodivanillate O-demethylase oxygenase subunit [EC:1.14.13.-]
         K15243  tftA; 2,4,5-trichlorophenoxyacetic acid oxygenase 1 [EC:1.14.13.-]
         K15244  tftB; 2,4,5-trichlorophenoxyacetic acid oxygenase 2 [EC:1.14.13.-]
         K15506  CYP98A8; cytochrome P450 family 98 subfamily A polypeptide 8 [EC:1.14.13.-]
         K15760  tmoA, tbuA1, touA; toluene monooxygenase system protein A [EC: 1.14.13.-]
         K15761  tmoB, tbuU, touB; toluene monooxygenase system protein B [EC: 1.14.13.-]
         K15763  tmoD, tbuV, touD; toluene monooxygenase system protein D [EC: 1.14.13.-]
         K15764  tmoE, tbuA2, touE; toluene monooxygenase system protein E [EC: 1.14.13.-]
         K15768  tsaM; p-toluenesulfonate methyl-monooxygenase oxygenase component TsaM [EC:1.14.13.-]
         K15966  mtmOIV; monooxygenase [EC:1.14.13.-]
         K17683  CYP2A6; cytochrome P450 family 2 subfamily A polypeptide 6 [EC:1.14.13.-]
         K17689  CYP3A4; cytochrome P450 family 3 subfamily A polypeptide 4 [EC: 1.14.13.-]
         K17709  CYP2B6; cytochrome P450 family 2 subfamily B polypeptide 6 [EC:1.14.13.-]
         K18386  PAXM, ATMM, LTMM; FAD dependent monooxygenase [EC:1.14.13.-]
         K18388  PAXP, ATMP, CYP653C; cytochrome P450 monooxygenase [EC:1.14.13.-]
         K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase [EC:1.14.13.-]
         K18392  LTMP, TERP; cytochrome P450 monooxygenase [EC:1.14.13.-]
         K18393  LTMQ, TERQ; cytochrome P450 monooxygenase [EC:1.14.13.-]
         K18395  LTMJ; cytochrome P450 monooxygenase [EC:1.14.13.-]
         K19106  nocL; nocardicin N-oxygenase [EC:1.14.13.-]
         K19982  prnD; aminopyrrolnitrin oxygenase [EC:1.14.13.-]
         K22800  auaF; aurachin D monooxygenase [EC:1.14.13.-]
         K22801  auaJ; aurachin B monooxygenase [EC:1.14.13.-]
         K23662  CYP98A9; cytochrome P450 family 98 subfamily A polypeptide 9 [EC:1.14.13.-]
         K23808  CYP72A67; cytochrome P450 family 72 subfamily A polypeptide 67 [EC:1.14.13.-]
     1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
     1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
     1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
     1.14.17  With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor
     1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
     1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
     1.14.20  With 2-oxoglutarate as one donor, and the other dehydrogenated
     1.14.21  With NADH or NADPH as one donor, and the other dehydrogenated
     1.14.99  Miscellaneous
     1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.15  Acting on superoxide as acceptor
   1.16  Oxidizing metal ions
   1.17  Acting on CH or CH2 groups
   1.18  Acting on iron-sulfur proteins as donors
   1.19  Acting on reduced flavodoxin as donor
   1.20  Acting on phosphorus or arsenic in donors
   1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.23  Reducing C-O-C group as acceptor
   1.97  Other oxidoreductases
 2. Transferases
 3. Hydrolases
 4. Lyases
 5. Isomerases
 6. Ligases
 7. Translocases

Last updated: September 19, 2020
EC number data are obtained from ExplorEnz