Transcription Factors

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1st Level  2nd Level  3rd Level  4th Level 

 Eukaryotic type
   Basic leucine zipper (bZIP)
   Basic helix-loop-helix (bHLH)
   Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Other basic domains
   Zinc finger
     Cys4 thyroid hormone-like
     Cys4 hepatocyte nuclear factor 4-like
     Cys4 estrogen-like
     Cys4 nerve growth factor IB-like
     Cys4 Fushi tarazu-F1-like
     Cys4 germ cell nuclear factor
     Cys4 Knirps/DAX 1-like
     Cys4 GATA-factors
     Cys4 Trithorax
     Other Cys4 zinc finger factors
     Cys2His2 ubiquitous factors
     Cys2His2 developmental/cell cycle regulators, Egr/Krox
     Cys2His2 developmental/cell cycle regulators, Krueppel-like
       K09204  KLF1; krueppel-like factor 1
       K17845  KLF2; krueppel-like factor 2
       K15605  KLF3; krueppel-like factor 3
       K17846  KLF4; krueppel-like factor 4
       K09206  KLF5; krueppel-like factor 5
       K09207  KLF6_7; krueppel-like factor 6/7
       K09205  KLF8_12; krueppel-like factor 8/12
       K09208  KLF9S, BTEB; krueppel-like factor 9/13/14/16
       K09209  KLF10_11, TIEG; krueppel-like factor 10/11
       K09210  KLF15; krueppel-like factor 15
       K09211  KLF17; krueppel-like factor 17
       K09215  OSR, ODD; odd-skipped
       K09216  OVOL; ovo
       K05707  SNAI1; snail 1
       K05706  SNAI2, SLUG; snail 2
       K09217  SNAI3; snail 3
       K09219  SCRT; scratch
       K04462  MECOM, EVI1; ecotropic virus integration site 1 protein
       K22534  PRDM5; PR domain zinc finger protein 5
       K22410  PRDM16; PR domain zinc finger protein 16
       K12458  ZNF274; zinc finger protein 274
       K22870  ZNF423; zinc finger protein 423
       K22411  ZNF516; zinc finger protein 516
       K09220  IKZF, ZNFN1A; IKAROS family zinc finger protein
       K09221  MZF1; myeloid zinc finger protein 1
       K09222  REST; RE1-silencing transcription factor
       K09223  GFI1; growth factor independent 1
       K15618  BCL6; B-cell lymphoma 6 protein
       K22648  BCL6B; B-cell CLL/lymphoma 6 member B protein
       K09231  KR; krueppel
       K13943  CBT; cabut
       K09213  HB; hunchback
       K09214  GL; glass
       K02215  CF2; chorion factor 2
       K22535  DRM; drumstick
     Cys2His2 developmental/cell cycle regulators, GLI-like
     Cys2His2 developmental/cell cycle regulators, Others
     Cys2His2 metabolic regulators in fungi
     Cys2His2 large factors with NF-6B-like binding properties
     Other Cys2His2 zinc factors
     Cys2His2Cys zinc factors
     Cys3His zinc factors
     Cys6 metabolic regulators in fungi
     Cys4HisCys3 PHD fingers
     Zinc fingers of alternating composition
   Helix-turn-helix
   beta-Scaffold factors with minor groove contacts
   Other transcription factors
 
 Prokaryotic type

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Last updated: June 1, 2020
Classification taken and modified from TRANSFAC 7.0