DNA Repair and Recombination Proteins

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 Eukaryotic type
 
 Prokaryotic type
   SSBR (single strand breaks repair)
     Direct repair
     BER (base exicision repair)
     NER (nucleotide excision repair)
     MMR (mismatch excision repair)
       Mismatch and loop recognition factors
       Molecular matchmaker
       Strand discrimination factor
       DNA exonucleases
         K01141  sbcB, exoI; exodeoxyribonuclease I [EC:3.1.11.1]
         K03601  xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
         K03602  xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
         K10857  exoX; exodeoxyribonuclease X [EC:3.1.11.-]
       DNA polymerase III holoenzyme
       DNA ligase
       Other MMR factors
   DSBR (double strand breaks repair)
     HR (homologous recombination)
       RecBC pathway proteins
         K03582  recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
         K03583  recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
         K03581  recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
         K03553  recA; recombination protein RecA
         K03550  ruvA; holliday junction DNA helicase RuvA
         K03551  ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
         K01159  ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
         K01160  rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
         K04066  priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
         K02686  priB; primosomal replication protein N
         K04067  priC; primosomal replication protein N''
         K02317  dnaT; DNA replication protein DnaT
         K01141  sbcB, exoI; exodeoxyribonuclease I [EC:3.1.11.1]
         K03546  sbcC, rad50; DNA repair protein SbcC/Rad50
         K03547  sbcD, mre11; DNA repair protein SbcD/Mre11
       RecFOR pathway proteins
       AddAB pathway proteins
       Other HR factor
       Archaeal homologous recombinant proteins
     NHEJ (non-homologous end-joining)
       Two-component NHEJ DNA repair complex
       SHIIR (short-homology-independent illegitimate recombination)
       SHDIR (short-homology-dependent illegitimate recombination)
         RecET pathway
         Facilitator
         Supressor
           K01141  sbcB, exoI; exodeoxyribonuclease I [EC:3.1.11.1]
           K03654  recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
           K03701  uvrA; excinuclease ABC subunit A
           K03702  uvrB; excinuclease ABC subunit B
           K03746  hns; DNA-binding protein H-NS
   TLS (translesion DNA synthesis) factors
   Other factors with a suspected DNA repair function

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Last updated: February 5, 2024