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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:mmu04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:mmu04012]
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04014 Ras signaling pathway [PATH:mmu04014]
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04015 Rap1 signaling pathway [PATH:mmu04015]
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04310 Wnt signaling pathway [PATH:mmu04310]
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04330 Notch signaling pathway [PATH:mmu04330]
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04340 Hedgehog signaling pathway [PATH:mmu04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:mmu04350]
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04390 Hippo signaling pathway [PATH:mmu04390]
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species [PATH:mmu04392]
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04370 VEGF signaling pathway [PATH:mmu04370]
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04371 Apelin signaling pathway [PATH:mmu04371]
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04630 JAK-STAT signaling pathway [PATH:mmu04630]
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04064 NF-kappa B signaling pathway [PATH:mmu04064]
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04668 TNF signaling pathway [PATH:mmu04668]
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04066 HIF-1 signaling pathway [PATH:mmu04066]
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04068 FoxO signaling pathway [PATH:mmu04068]
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21803 Tgfb1; transforming growth factor, beta 1
21808 Tgfb2; transforming growth factor, beta 2
21809 Tgfb3; transforming growth factor, beta 3
21812 Tgfbr1; transforming growth factor, beta receptor I
21813 Tgfbr2; transforming growth factor, beta receptor II
17128 Smad4; SMAD family member 4
17127 Smad3; SMAD family member 3
20869 Stk11; serine/threonine kinase 11
105787 Prkaa1; protein kinase, AMP-activated, alpha 1 catalytic subunit
108079 Prkaa2; protein kinase, AMP-activated, alpha 2 catalytic subunit
19079 Prkab1; protein kinase, AMP-activated, beta 1 non-catalytic subunit
108097 Prkab2; protein kinase, AMP-activated, beta 2 non-catalytic subunit
19082 Prkag1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
241113 Prkag3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit
108099 Prkag2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit
18099 Nlk; nemo like kinase
27401 Skp2; S-phase kinase-associated protein 2
17246 Mdm2; transformed mouse 3T3 cell double minute 2
73251 Setd7; SET domain containing (lysine methyltransferase) 7
12914 Crebbp; CREB binding protein
328572 Ep300; E1A binding protein p300
93759 Sirt1; sirtuin 1
252870 Usp7; ubiquitin specific peptidase 7
20528 Slc2a4; solute carrier family 2 (facilitated glucose transporter), member 4
26419 Mapk8; mitogen-activated protein kinase 8
26420 Mapk9; mitogen-activated protein kinase 9
26414 Mapk10; mitogen-activated protein kinase 10
58231 Stk4; serine/threonine kinase 4
16000 Igf1; insulin-like growth factor 1
16001 Igf1r; insulin-like growth factor I receptor
16334 Ins2; insulin II
16333 Ins1; insulin I
16337 Insr; insulin receptor
16367 Irs1; insulin receptor substrate 1
384783 Irs2; insulin receptor substrate 2
16369 Irs3; insulin receptor substrate 3
16370 Irs4; insulin receptor substrate 4
18706 Pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
18707 Pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
74769 Pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
18709 Pik3r2; phosphoinositide-3-kinase regulatory subunit 2
18708 Pik3r1; phosphoinositide-3-kinase regulatory subunit 1
18710 Pik3r3; phosphoinositide-3-kinase regulatory subunit 3
18607 Pdpk1; 3-phosphoinositide dependent protein kinase 1
12675 Chuk; conserved helix-loop-helix ubiquitous kinase
16150 Ikbkb; inhibitor of kappaB kinase beta
19211 Pten; phosphatase and tensin homolog
11651 Akt1; thymoma viral proto-oncogene 1
11652 Akt2; thymoma viral proto-oncogene 2
23797 Akt3; thymoma viral proto-oncogene 3
20393 Sgk1; serum/glucocorticoid regulated kinase 1
27219 Sgk2; serum/glucocorticoid regulated kinase 2
170755 Sgk3; serum/glucocorticoid regulated kinase 3
56458 Foxo1; forkhead box O1
56484 Foxo3; forkhead box O3
54601 Foxo4; forkhead box O4
329934 Foxo6; forkhead box O6
14816 Grm1; glutamate receptor, metabotropic 1
26557 Homer2; homer scaffolding protein 2
26556 Homer1; homer scaffolding protein 1
26558 Homer3; homer scaffolding protein 3
216439 Agap2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
27373 Csnk1e; casein kinase 1, epsilon
16193 Il6; interleukin 6
16153 Il10; interleukin 10
20848 Stat3; signal transducer and activator of transcription 3
13645 Egf; epidermal growth factor
13649 Egfr; epidermal growth factor receptor
14784 Grb2; growth factor receptor bound protein 2
20662 Sos1; SOS Ras/Rac guanine nucleotide exchange factor 1
20663 Sos2; SOS Ras/Rho guanine nucleotide exchange factor 2
15461 Hras; Harvey rat sarcoma virus oncogene
16653 Kras; Kirsten rat sarcoma viral oncogene homolog
18176 Nras; neuroblastoma ras oncogene
109880 Braf; Braf transforming gene
110157 Raf1; v-raf-leukemia viral oncogene 1
11836 Araf; Araf proto-oncogene, serine/threonine kinase
26395 Map2k1; mitogen-activated protein kinase kinase 1
26396 Map2k2; mitogen-activated protein kinase kinase 2
26413 Mapk1; mitogen-activated protein kinase 1
26417 Mapk3; mitogen-activated protein kinase 3
26416 Mapk14; mitogen-activated protein kinase 14
19094 Mapk11; mitogen-activated protein kinase 11
29857 Mapk12; mitogen-activated protein kinase 12
26415 Mapk13; mitogen-activated protein kinase 13
12566 Cdk2; cyclin-dependent kinase 2
15469 Prmt1; protein arginine N-methyltransferase 1
15228 Foxg1; forkhead box G1
268697 Ccnb1; cyclin B1
12442 Ccnb2; cyclin B2
209091 Ccnb3; cyclin B3
12443 Ccnd1; cyclin D1
12444 Ccnd2; cyclin D2
12452 Ccng2; cyclin G2
12579 Cdkn2b; cyclin dependent kinase inhibitor 2B
12581 Cdkn2d; cyclin dependent kinase inhibitor 2D
12575 Cdkn1a; cyclin-dependent kinase inhibitor 1A (P21)
12576 Cdkn1b; cyclin-dependent kinase inhibitor 1B
19651 Rbl2; RB transcriptional corepressor like 2
18817 Plk1; polo like kinase 1
20620 Plk2; polo like kinase 2
12795 Plk3; polo like kinase 3
20873 Plk4; polo like kinase 4
13197 Gadd45a; growth arrest and DNA-damage-inducible 45 alpha
17873 Gadd45b; growth arrest and DNA-damage-inducible 45 beta
23882 Gadd45g; growth arrest and DNA-damage-inducible 45 gamma
14103 Fasl; Fas ligand (TNF superfamily, member 6)
12125 Bcl2l11; BCL2-like 11 (apoptosis facilitator)
22035 Tnfsf10; tumor necrosis factor (ligand) superfamily, member 10
12053 Bcl6; B cell leukemia/lymphoma 6
12176 Bnip3; BCL2/adenovirus E1B interacting protein 3
67526 Atg12; autophagy related 12
57436 Gabarapl1; gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
56486 Gabarap; gamma-aminobutyric acid receptor associated protein
93739 Gabarapl2; gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
12359 Cat; catalase
20656 Sod2; superoxide dismutase 2, mitochondrial
11920 Atm; ataxia telangiectasia mutated
18534 Pck1; phosphoenolpyruvate carboxykinase 1, cytosolic
74551 Pck2; phosphoenolpyruvate carboxykinase 2 (mitochondrial)
14377 G6pc; glucose-6-phosphatase, catalytic
14378 G6pc2; glucose-6-phosphatase, catalytic, 2
68401 G6pc3; glucose 6 phosphatase, catalytic, 3
16197 Il7r; interleukin 7 receptor
16598 Klf2; Kruppel-like factor 2 (lung)
13609 S1pr1; sphingosine-1-phosphate receptor 1
13611 S1pr4; sphingosine-1-phosphate receptor 4
19373 Rag1; recombination activating 1
19374 Rag2; recombination activating gene 2
66822 Fbxo25; F-box protein 25
67731 Fbxo32; F-box protein 32
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K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
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04020 Calcium signaling pathway [PATH:mmu04020]
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04070 Phosphatidylinositol signaling system [PATH:mmu04070]
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04072 Phospholipase D signaling pathway [PATH:mmu04072]
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04071 Sphingolipid signaling pathway [PATH:mmu04071]
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04024 cAMP signaling pathway [PATH:mmu04024]
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04022 cGMP-PKG signaling pathway [PATH:mmu04022]
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04151 PI3K-Akt signaling pathway [PATH:mmu04151]
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04152 AMPK signaling pathway [PATH:mmu04152]
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04150 mTOR signaling pathway [PATH:mmu04150]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09141 Transport and catabolism
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09143 Cell growth and death
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04110 Cell cycle [PATH:mmu04110]
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04111 Cell cycle - yeast
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04112 Cell cycle - Caulobacter
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04113 Meiosis - yeast
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04114 Oocyte meiosis [PATH:mmu04114]
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04210 Apoptosis [PATH:mmu04210]
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04214 Apoptosis - fly
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04215 Apoptosis - multiple species [PATH:mmu04215]
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04216 Ferroptosis [PATH:mmu04216]
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04217 Necroptosis [PATH:mmu04217]
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04115 p53 signaling pathway [PATH:mmu04115]
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11920 Atm; ataxia telangiectasia mutated
50883 Chek2; checkpoint kinase 2
245000 Atr; ataxia telangiectasia and Rad3 related
12649 Chek1; checkpoint kinase 1
98376 Gorab; golgin, RAB6-interacting
12578 Cdkn2a; cyclin dependent kinase inhibitor 2A
17246 Mdm2; transformed mouse 3T3 cell double minute 2
17248 Mdm4; transformed mouse 3T3 cell double minute 4
22059 Trp53; transformation related protein 53
12575 Cdkn1a; cyclin-dependent kinase inhibitor 1A (P21)
12443 Ccnd1; cyclin D1
12444 Ccnd2; cyclin D2
12445 Ccnd3; cyclin D3
12567 Cdk4; cyclin-dependent kinase 4
12571 Cdk6; cyclin-dependent kinase 6
12447 Ccne1; cyclin E1
12448 Ccne2; cyclin E2
12566 Cdk2; cyclin-dependent kinase 2
55948 Sfn; stratifin
67874 Rprm; reprimo, TP53 dependent G2 arrest mediator candidate
268697 Ccnb1; cyclin B1
12442 Ccnb2; cyclin B2
12534 Cdk1; cyclin-dependent kinase 1
13197 Gadd45a; growth arrest and DNA-damage-inducible 45 alpha
17873 Gadd45b; growth arrest and DNA-damage-inducible 45 beta
23882 Gadd45g; growth arrest and DNA-damage-inducible 45 gamma
29870 Gtse1; G two S phase expressed protein 1
14102 Fas; Fas (TNF receptor superfamily member 6)
57913 Pidd1; p53 induced death domain protein 1
21933 Tnfrsf10b; tumor necrosis factor receptor superfamily, member 10b
12370 Casp8; caspase 8
12122 Bid; BH3 interacting domain death agonist
12028 Bax; BCL2-associated X protein
58801 Pmaip1; phorbol-12-myristate-13-acetate-induced protein 1
170770 Bbc3; BCL2 binding component 3
30954 Siva1; SIVA1, apoptosis-inducing factor
12048 Bcl2l1; BCL2-like 1
12043 Bcl2; B cell leukemia/lymphoma 2
13663 Ei24; etoposide induced 2.4 mRNA
66940 Shisa5; shisa family member 5
64058 Perp; PERP, TP53 apoptosis effector
22401 Zmat3; zinc finger matrin type 3
20437 Siah1a; siah E3 ubiquitin protein ligase 1A
20438 Siah1b; siah E3 ubiquitin protein ligase 1B
13063 Cycs; cytochrome c, somatic
13067 Cyct; cytochrome c, testis
11783 Apaf1; apoptotic peptidase activating factor 1
12371 Casp9; caspase 9
12367 Casp3; caspase 3
71361 Aifm2; apoptosis-inducing factor, mitochondrion-associated 2
16009 Igfbp3; insulin-like growth factor binding protein 3
16000 Igf1; insulin-like growth factor 1
18787 Serpine1; serine (or cysteine) peptidase inhibitor, clade E, member 1
107831 Adgrb1; adhesion G protein-coupled receptor B1
12521 Cd82; CD82 antigen
21825 Thbs1; thrombospondin 1
20724 Serpinb5; serine (or cysteine) peptidase inhibitor, clade B, member 5
107986 Ddb2; damage specific DNA binding protein 2
382985 Rrm2b; ribonucleotide reductase M2 B (TP53 inducible)
20135 Rrm2; ribonucleotide reductase M2
140742 Sesn1; sestrin 1
75747 Sesn3; sestrin 3
230784 Sesn2; sestrin 2
19211 Pten; phosphatase and tensin homolog
22084 Tsc2; TSC complex subunit 2
68428 Steap3; STEAP family member 3
26374 Cop1; COP1, E3 ubiquitin ligase
68098 Rchy1; ring finger and CHY zinc finger domain containing 1
12450 Ccng1; cyclin G1
12452 Ccng2; cyclin G2
53892 Ppm1d; protein phosphatase 1D magnesium-dependent, delta isoform
22062 Trp73; transformation related protein 73
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K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K04596 ADGRB1; adhesion G protein-coupled receptor B1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
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04218 Cellular senescence [PATH:mmu04218]
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09144 Cellular community - eukaryotes
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09145 Cellular community - prokaryotes
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09142 Cell motility
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Mus musculus (mouse)