Ubiquitin System - Mus musculus (mouse)

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     KO
 Ubiquitins and ubiquitin-like proteins
 
 Ubiquitin-activating enzymes (E1)
 
 Ubiquitin-conjugating enzymes (E2)
 
 Ubiquitin ligases (E3)
   HECT type E3
   U-box type E3
   Single Ring-finger type E3
   Atypical E3
   UBL E3 ligases
   Multi subunit Ring-finger type E3
     SCF complex
     ECV complex
     Cul3 complex
     Cul4 complex
       Ring finger protein
       Cullin
       Adoptor protein
       Target recognizing subunit (DCAF)
         107986 Ddb2; damage specific DNA binding protein 2
         71991 Ercc8; excision repaiross-complementing rodent repair deficiency, complementation group 8
         76375 Det1; de-etiolated homolog 1 (Arabidopsis)
         26374 Cop1; COP1, E3 ubiquitin ligase
         66498 Dda1; DET1 and DDB1 associated 1
         58799 Crbn; cereblon
         240832 Tor1aip2; torsin A interacting protein 2
         56407 Trpc4ap; transient receptor potential cation channel, subfamily C, member 4 associated protein
         321006 Dcaf1; DDB1 and CUL4 associated factor 1
         76843 Dtl; denticleless E3 ubiquitin protein ligase
         73828 Dcaf4; DDB1 and CUL4 associated factor 4
         320808 Dcaf5; DDB1 and CUL4 associated factor 5
         74106 Dcaf6; DDB1 and CUL4 associated factor 6
         71833 Dcaf7; DDB1 and CUL4 associated factor 7
         98193 Dcaf8; DDB1 and CUL4 associated factor 8
         230796 Wdtc1; WD and tetratricopeptide repeats 1
         242418 Dcaf10; DDB1 and CUL4 associated factor 10
         28199 Dcaf11; DDB1 and CUL4 associated factor 11
         68970 Dcaf12; DDB1 and CUL4 associated factor 12
         245403 Dcaf12l2; DDB1 and CUL4 associated factor 12-like 2
         245404 Dcaf12l1; DDB1 and CUL4 associated factor 12-like 1
         223499 Dcaf13; DDB1 and CUL4 associated factor 13
         83946 Phip; pleckstrin homology domain interacting protein
         212123 Dcaf15; DDB1 and CUL4 associated factor 15
         75763 Dcaf17; DDB1 and CUL4 associated factor 17
         382236 Brwd3; bromodomain and WD repeat domain containing 3
         93871 Brwd1; bromodomain and WD repeat domain containing 1
         226757 Wdr26; WD repeat domain 26
         545085 Wdr70; WD repeat domain 70
         241627 Wdr76; WD repeat domain 76
K10140 DDB2; DNA damage-binding protein 2 
K10570 ERCC8; DNA excision repair protein ERCC-8 
K10571 DET1; de-etiolated-1 
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27] 
K11792 DDA1; DET1- and DDB1-associated protein 1 
K11793 CRBN; cereblon 
K11794 IFRG15; IFRG15 protein 
K11796 TRPC4AP; Trpc4-associated protein 
K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1] 
K11790 DTL; denticleless 
K11799 DCAF4; DDB1- and CUL4-associated factor 4 
K11800 DCAF5; DDB1- and CUL4-associated factor 5 
K11795 DCAF6; DDB1- and CUL4-associated factor 6 
K11805 DCAF7; DDB1- and CUL4-associated factor 7 
K11804 DCAF8; DDB1- and CUL4-associated factor 8 
K11807 WDTC1; WD and tetratricopeptide repeats protein 1 
K11802 DCAF10; DDB1- and CUL4-associated factor 10 
K11801 DCAF11; DDB1- and CUL4-associated factor 11 
K11803 DCAF12; DDB1- and CUL4-associated factor 12 
K11803 DCAF12; DDB1- and CUL4-associated factor 12 
K11803 DCAF12; DDB1- and CUL4-associated factor 12 
K11806 DCAF13; DDB1- and CUL4-associated factor 13 
K11797 PHIP; PH-interacting protein 
K11791 DCAF15; DDB1- and CUL4-associated factor 15 
K23331 DCAF17; DDB1- and CUL4-associated factor 17 
K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3 
K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3 
K22382 WDR26; WD repeat-containing protein 26 
K24752 WDR70; WD repeat-containing protein 70 
K24755 WDR76; WD repeat-containing protein 76 
     ECS complex
     Cul7 complex
     Cul9 complex
     APC/C
     BRCC complex
     KPC complex
     LUBAC complex
     CTLH complex
     ERAD complex
     SLX5-SLX8 complex
     Multi subunit type E3 associated proteins
 
 Deubiquitinating enzyme (DUB)

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Last updated: February 24, 2021