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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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 09150 Organismal Systems
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09151 Immune system
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09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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04970 Salivary secretion [PATH:rno04970]
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04971 Gastric acid secretion [PATH:rno04971]
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04972 Pancreatic secretion [PATH:rno04972]
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04976 Bile secretion [PATH:rno04976]
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04973 Carbohydrate digestion and absorption [PATH:rno04973]
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04974 Protein digestion and absorption [PATH:rno04974]
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04975 Fat digestion and absorption [PATH:rno04975]
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04979 Cholesterol metabolism [PATH:rno04979]
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04977 Vitamin digestion and absorption [PATH:rno04977]
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04980 Cobalamin transport and metabolism [PATH:rno04980]
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04978 Mineral absorption [PATH:rno04978]
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 25548 Slc34a1; sodium-dependent phosphate transport protein 2A
84395 Slc34a2; sodium-dependent phosphate transport protein 2B
246234 Slc34a3; sodium-dependent phosphate transport protein 2C
24873 Vdr; vitamin D3 receptor
293874 Trpm6; transient receptor potential cation channel subfamily M member 6 isoform X1
679906 Trpm7; transient receptor potential cation channel subfamily M member 7
114246 Trpv6; transient receptor potential cation channel subfamily V member 6
29715 Slc8a1; sodium/calcium exchanger 1 isoform 6 precursor
140447 Slc8a2; sodium/calcium exchanger 2 precursor
140448 Slc8a3; sodium/calcium exchanger 3 precursor
29600 Atp2b4; plasma membrane calcium-transporting ATPase 4
29599 Atp2b3; plasma membrane calcium-transporting ATPase 3
24215 Atp2b2; plasma membrane calcium-transporting ATPase 2
29598 Atp2b1; plasma membrane calcium-transporting ATPase 1 isoform 3
24249 S100g; protein S100-G
114629 Slc26a3; chloride anion exchanger
301010 Slc26a6; solute carrier family 26 member 6
304784 Slc26a9; solute carrier family 26 member 9
29232 Clcn2; chloride channel protein 2
24784 Slc9a3; sodium/hydrogen exchanger 3 precursor
25552 Slc5a1; sodium/glucose cotransporter 1
365549 Slc5a1l1; uncharacterized protein LOC365549
664630 Slc6a19; sodium-dependent neutral amino acid transporter B(0)AT1
24211 Atp1a1; sodium/potassium-transporting ATPase subunit alpha-1 precursor
24212 Atp1a2; sodium/potassium-transporting ATPase subunit alpha-2 precursor
24213 Atp1a3; sodium/potassium-transporting ATPase subunit alpha-3
29132 Atp1a4; sodium/potassium-transporting ATPase subunit alpha-4
84396 Atp1b4; protein ATP1B4
25650 Atp1b1; sodium/potassium-transporting ATPase subunit beta-1
24214 Atp1b2; sodium/potassium-transporting ATPase subunit beta-2
25390 Atp1b3; sodium/potassium-transporting ATPase subunit beta-3
29639 Fxyd2; sodium/potassium-transporting ATPase subunit gamma isoform a
303333 Slc46a1; proton-coupled folate transporter
24451 Hmox1; heme oxygenase 1
79239 Hmox2; heme oxygenase 2
295669 Cybrd1; plasma membrane ascorbate-dependent reductase CYBRD1
25715 Slc11a2; natural resistance-associated macrophage protein 2 isoform 1
25319 Fth1; ferritin heavy chain
302548 Fth1l1; ferritin heavy chain-like
29292 Ftl1; ferritin light chain 1
100360087 ferritin light chain 1
100359668 Ftl1l2; ferritin light chain 1-like
120102993 ferritin light chain 1-like
100362384 ferritin light chain 1-like
499244 Ftl1l7; ferritin light chain 1-like
500804 Ftl1l5; ferritin light chain 1-like
501644 Ftl1l1; ferritin light chain 1-like 1
170840 Slc40a1; solute carrier family 40 member 1
117240 Heph; hephaestin precursor
500946 Hephl1; ferroxidase HEPHL1
24825 Tf; serotransferrin precursor
315963 Inhca; Inhibitor of carbonic anhydrase precursor
300051 Slc39a4; zinc transporter ZIP4 precursor
58976 Slc30a1; proton-coupled zinc antiporter SLC30A1
171135 Slc31a1; high affinity copper uptake protein 1
297738 Steap1; metalloreductase STEAP1
312052 Steap2; metalloreductase STEAP2
689415 Mt2A; metallothionein-2
24567 Mt1; metallothionein-1
84355 Atox1; copper transport protein ATOX1
24218 Atp7b; copper-transporting ATPase 2
24941 Atp7a; copper-transporting ATPase 1
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K14683 SLC34A; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K14683 SLC34A; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K14683 SLC34A; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K08539 VDR; vitamin D3 receptor
K04981 TRPM6; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04975 TRPV6; transient receptor potential cation channel subfamily V member 6
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K14734 S100G; protein S100-G
K14078 SLC26A3; solute carrier family 26 (chloride anion exchanger), member 3
K14704 SLC26A6; solute carrier family 26 (sulfate anion transporter), member 6
K14706 SLC26A9; solute carrier family 26 (sulfate anion transporter), member 9
K05011 CLCN2; chloride channel 2
K12040 SLC9A3; solute carrier family 9 (sodium/hydrogen exchanger), member 3
K14158 SLC5A1; solute carrier family 5 (sodium/glucose cotransporter), member 1
K14158 SLC5A1; solute carrier family 5 (sodium/glucose cotransporter), member 1
K05334 SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K14613 SLC46A1; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K21418 HMOX2; heme oxygenase 2 [EC:1.14.14.18]
K08370 CYBRD1; plasma membrane ascorbate-dependent reductase [EC:7.2.1.3]
K21398 SLC11A2; natural resistance-associated macrophage protein 2
K00522 FTH1; ferritin heavy chain [EC:1.16.3.1]
K00522 FTH1; ferritin heavy chain [EC:1.16.3.1]
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K13625 FTL; ferritin light chain
K14685 SLC40A1; solute carrier family 40 (iron-regulated transporter), member 1
K14735 HEPH; hephaestin [EC:1.16.3.1]
K14735 HEPH; hephaestin [EC:1.16.3.1]
K14736 TF; transferrin
K14736 TF; transferrin
K14710 SLC39A4; solute carrier family 39 (zinc transporter), member 4
K14688 SLC30A1; solute carrier family 30 (zinc transporter), member 1
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K14737 STEAP1; metalloreductase STEAP1 [EC:1.16.1.-]
K14738 STEAP2; metalloreductase STEAP2 [EC:1.16.1.-]
K14739 MT1_2; metallothionein 1/2
K14739 MT1_2; metallothionein 1/2
K07213 ATOX1; copper chaperone
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09161 Cancer: overview
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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01521 EGFR tyrosine kinase inhibitor resistance [PATH:rno01521]
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01524 Platinum drug resistance [PATH:rno01524]
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171135 Slc31a1; high affinity copper uptake protein 1
24218 Atp7b; copper-transporting ATPase 2
24941 Atp7a; copper-transporting ATPase 1
81869 Gstm7; glutathione S-transferase Mu 7
24421 Gsta1; glutathione S-transferase alpha-3
24422 Gsta2; glutathione S-transferase alpha-1
24424 Gstm2; glutathione S-transferase Mu 2
25260 Gstt1; glutathione S-transferase theta-1
29487 Gstt2; glutathione S-transferase theta-2
57298 Gstm3; glutathione S-transferase Mu 3
295037 Mgst2; microsomal glutathione S-transferase 2
171341 Mgst1; microsomal glutathione S-transferase 1
64352 Gstm5; glutathione S-transferase Mu 5
289197 Mgst3; microsomal glutathione S-transferase 3
114846 Gsto1; glutathione S-transferase omega-1
300850 Gsta4; glutathione S-transferase alpha-4
309465 Gsto2; glutathione S-transferase omega-2
499689 Gstm4; glutathione S-transferase Mu 4
24423 Gstm1; glutathione S-transferase Mu 1
494499 Gsta5; glutathione S-transferase alpha-2
494500 Gsta3; glutathione S-transferase alpha-5 isoform 1
499688 Gstm6; glutathione S-transferase Mu 6
501110 Gsta6; glutathione S-transferase A6
499422 Gstt3; glutathione S-transferase, theta 3
686922 Gstt4; glutathione S-transferase theta-4
295362 Gstm6l; glutathione S-transferase, mu 6-like
498340 Mgst3l1; glutathione S-transferase 3, mitochondrial-like
24426 Gstp1; glutathione S-transferase P
100911464 glutathione S-transferase P-like
293656 Gstp3; Glutathione S-transferase P-like isoform 2
25303 Abcc2; ATP-binding cassette sub-family C member 2
316235 Polh; DNA polymerase eta
309812 Rev3l; DNA polymerase zeta catalytic subunit
81709 Msh2; DNA mismatch repair protein Msh2
499505 Msh3; DNA mismatch repair protein Msh3
100360342 Msh6; DNA mismatch repair protein Msh6
81685 Mlh1; DNA mismatch repair protein Mlh1
298074 Xpa; DNA repair protein complementing XP-A cells isoform 1
292673 Ercc1; DNA excision repair protein ERCC-1
360243 Top2a; DNA topoisomerase 2-alpha
361100 Top2b; DNA topoisomerase 2-beta
497672 Brca1; breast cancer type 1 susceptibility protein homolog
300711 Atm; serine-protein kinase ATM
24842 Tp53; cellular tumor antigen p53
25163 Cdkn2a; cyclin-dependent kinase inhibitor 2A
314856 Mdm2; E3 ubiquitin-protein ligase Mdm2
246097 Fas; tumor necrosis factor receptor superfamily member 6 precursor
24887 Bax; apoptosis regulator BAX
367149 Bax-ps1; apoptosis regulator BAX-like
681314 apoptosis regulator BAX-like
116502 Bak1; bcl-2 homologous antagonist/killer
492821 Pmaip1; phorbol-12-myristate-13-acetate-induced protein 1
317673 Bbc3; bcl-2-binding component 3
25385 Faslg; tumor necrosis factor ligand superfamily member 6
266610 Fadd; FAS-associated death domain protein
64044 Casp8; caspase-8
25402 Casp3; caspase-3
64625 Bid; BH3-interacting domain death agonist
60371 Birc2; baculoviral IAP repeat-containing protein 2
78971 Birc3; baculoviral IAP repeat-containing protein 3
63879 Xiap; E3 ubiquitin-protein ligase XIAP
64041 Birc5; baculoviral IAP repeat-containing protein 5
24337 Erbb2; receptor tyrosine-protein kinase erbB-2 precursor
85243 Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
170911 Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
366508 Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
134484121 LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like
25513 Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha
60664 Pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma
29741 Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta
81745 Pdpk1; 3-phosphoinositide-dependent protein kinase 1
24185 Akt1; RAC-alpha serine/threonine-protein kinase
25233 Akt2; RAC-beta serine/threonine-protein kinase
29414 Akt3; RAC-gamma serine/threonine-protein kinase
114851 Cdkn1a; cyclin-dependent kinase inhibitor 1
365057 Map3k5; mitogen-activated protein kinase kinase kinase 5
116590 Mapk1; mitogen-activated protein kinase 1
50689 Mapk3; mitogen-activated protein kinase 3
64639 Bad; bcl2-associated agonist of cell death
24888 Bcl2l1; bcl-2-like protein 1 isoform 2
24224 Bcl2; apoptosis regulator Bcl-2
25309 Cycs; cytochrome c, somatic
25310 Cyct; cytochrome c, testis-specific
120099910 cytochrome c, somatic-like
690675 Cycsl2; cytochrome c, somatic-like
679794 Cycsl1; cytochrome c, somatic-like
290019 Cycsl3; cytochrome c, somatic-like
78963 Apaf1; apoptotic protease-activating factor 1
58918 Casp9; caspase-9
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K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K02159 BAX; apoptosis regulator BAX
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
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01523 Antifolate resistance [PATH:rno01523]
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01522 Endocrine resistance [PATH:rno01522]
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Rattus norvegicus (rat)