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KO |
 09100 Metabolism
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 09120 Genetic Information Processing
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09121 Transcription
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09122 Translation
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09123 Folding, sorting and degradation
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09124 Replication and repair
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03030 DNA replication [PATH:rno03030]
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 54304 Ssbp1; single-stranded DNA-binding protein, mitochondrial precursor
298933 Rnaseh1; ribonuclease H1 isoform 1 precursor
287524 Rpa1; replication protein A 70 kDa DNA-binding subunit
25737 Pcna; proliferating cell nuclear antigen
84490 Fen1; flap endonuclease 1
81513 Lig1; DNA ligase 1
85241 Pola1; DNA polymerase alpha catalytic subunit
85242 Pola2; DNA polymerase alpha subunit B
246327 Prim1; DNA primase small subunit isoform 2
301323 Prim2; DNA primase large subunit
59294 Pold1; DNA polymerase delta catalytic subunit
289758 Pold2; DNA polymerase delta subunit 2
293144 Pold3; DNA polymerase delta subunit 3
361698 Pold4; DNA polymerase delta subunit 4
304573 Pole; DNA polymerase epsilon catalytic subunit A
299112 Pole2; DNA polymerase epsilon subunit 2
298098 Pole3; DNA polymerase epsilon subunit 3
100362333 DNA polymerase epsilon subunit 3
362385 Pole4; DNA polymerase epsilon subunit 4
312538 Mcm2; DNA replication licensing factor MCM2
316273 Mcm3; DNA replication licensing factor MCM3
29728 Mcm4; DNA replication licensing factor MCM4
291885 Mcm5; DNA replication licensing factor MCM5
29685 Mcm6; DNA replication licensing factor MCM6
288532 Mcm7; DNA replication licensing factor MCM7
59102 Rpa2; replication protein A 32 kDa subunit
296883 Rpa3; replication protein A 14 kDa subunit
89809 Rfc1; replication factor C subunit 1
288003 Rfc4; replication factor C subunit 4
116468 Rfc2; replication factor C subunit 2
304528 Rfc5; replication factor C subunit 5
288414 Rfc3; replication factor C subunit 3
364974 Rnaseh2a; ribonuclease H2 subunit A
361056 Rnaseh2b; ribonuclease H2 subunit B
100361939 Rnaseh2c; ribonuclease H2 subunit C
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K03111 ssb; single-strand DNA-binding protein
K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
K07466 RFA1; replication factor A1
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1; flap endonuclease-1 [EC:3.-.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
K02321 POLA2; DNA polymerase alpha subunit B
K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
K02685 PRI2; DNA primase large subunit
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
K10744 RNASEH2B; ribonuclease H2 subunit B
K10745 RNASEH2C; ribonuclease H2 subunit C
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03410 Base excision repair [PATH:rno03410]
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03420 Nucleotide excision repair [PATH:rno03420]
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03430 Mismatch repair [PATH:rno03430]
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03440 Homologous recombination [PATH:rno03440]
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03450 Non-homologous end-joining [PATH:rno03450]
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03460 Fanconi anemia pathway [PATH:rno03460]
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09130 Environmental Information Processing
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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09182 Protein families: genetic information processing
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03000 Transcription factors [BR:rno03000]
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03021 Transcription machinery [BR:rno03021]
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03019 Messenger RNA biogenesis [BR:rno03019]
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03041 Spliceosome [BR:rno03041]
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03011 Ribosome [BR:rno03011]
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03009 Ribosome biogenesis [BR:rno03009]
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03016 Transfer RNA biogenesis [BR:rno03016]
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03012 Translation factors [BR:rno03012]
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03110 Chaperones and folding catalysts [BR:rno03110]
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04131 Membrane trafficking [BR:rno04131]
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04121 Ubiquitin system [BR:rno04121]
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03051 Proteasome [BR:rno03051]
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03032 DNA replication proteins [BR:rno03032]
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313479 Orc1; origin recognition complex subunit 1
301430 Orc2; origin recognition complex subunit 2
313138 Orc3; origin recognition complex subunit 3
295596 Orc4; origin recognition complex subunit 4
362304 Orc5; origin recognition complex subunit 5
291927 Orc6; origin recognition complex subunit 6
292071 Cdt1; DNA replication factor Cdt1
360621 Cdc6; cell division control protein 6 homolog
312538 Mcm2; DNA replication licensing factor MCM2
316273 Mcm3; DNA replication licensing factor MCM3
29728 Mcm4; DNA replication licensing factor MCM4
291885 Mcm5; DNA replication licensing factor MCM5
29685 Mcm6; DNA replication licensing factor MCM6
288532 Mcm7; DNA replication licensing factor MCM7
114494 Ccna2; cyclin-A2
295052 Ccna1; cyclin-A1
362485 Ccne2; G1/S-specific cyclin-E2
25729 Ccne1; G1/S-specific cyclin-E1
362817 Cdk2; cyclin-dependent kinase 2
360908 Cdc7; cell division cycle 7-related protein kinase
499914 Gins1; DNA replication complex GINS protein PSF1
292058 Gins2; DNA replication complex GINS protein PSF2
307639 Gins3; DNA replication complex GINS protein PSF3
290842 Gins4; DNA replication complex GINS protein SLD5
315969 Topbp1; LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1
300057 Recql4; ATP-dependent DNA helicase Q4
287961 Cdc45; cell division control protein 45 homolog
296178 Mcm8; DNA helicase MCM8
499437 Mcm9; DNA helicase MCM9 isoform X2
307126 Mcm10; protein MCM10 homolog
500837 Helb; DNA helicase B isoform X1
691074 serine protease FAM111A-like
499322 Fam111a; FAM111 trypsin like peptidase A
85241 Pola1; DNA polymerase alpha catalytic subunit
85242 Pola2; DNA polymerase alpha subunit B
246327 Prim1; DNA primase small subunit isoform 2
301323 Prim2; DNA primase large subunit
304573 Pole; DNA polymerase epsilon catalytic subunit A
299112 Pole2; DNA polymerase epsilon subunit 2
298098 Pole3; DNA polymerase epsilon subunit 3
100362333 DNA polymerase epsilon subunit 3
362385 Pole4; DNA polymerase epsilon subunit 4
59294 Pold1; DNA polymerase delta catalytic subunit
289758 Pold2; DNA polymerase delta subunit 2
293144 Pold3; DNA polymerase delta subunit 3
361698 Pold4; DNA polymerase delta subunit 4
85472 Polg; DNA polymerase subunit gamma-1
303612 Polg2; DNA polymerase subunit gamma-2, mitochondrial
287524 Rpa1; replication protein A 70 kDa DNA-binding subunit
59102 Rpa2; replication protein A 32 kDa subunit
296883 Rpa3; replication protein A 14 kDa subunit
89809 Rfc1; replication factor C subunit 1
288003 Rfc4; replication factor C subunit 4
116468 Rfc2; replication factor C subunit 2
304528 Rfc5; replication factor C subunit 5
288414 Rfc3; replication factor C subunit 3
298933 Rnaseh1; ribonuclease H1 isoform 1 precursor
364974 Rnaseh2a; ribonuclease H2 subunit A
361056 Rnaseh2b; ribonuclease H2 subunit B
100361939 Rnaseh2c; ribonuclease H2 subunit C
25737 Pcna; proliferating cell nuclear antigen
84490 Fen1; flap endonuclease 1
305000 Exo1; exonuclease 1
81513 Lig1; DNA ligase 1
84350 Dnmt1; DNA (cytosine-5)-methyltransferase 1
444984 Dnmt3a; DNA (cytosine-5)-methyltransferase 3A isoform 1
444985 Dnmt3b; DNA (cytosine-5)-methyltransferase 3B
291137 Gmnn; geminin
688802 Mcidas; multicilin
25203 Ccnb1; G2/mitotic-specific cyclin-B1
363088 Ccnb2; G2/mitotic-specific cyclin-B2
100364016 G2/mitotic-specific cyclin-B2
317389 Ccnb3; G2/mitotic-specific cyclin-B3 isoform X2
54237 Cdk1; cyclin-dependent kinase 1
690237 Pot1b; protection of telomeres protein 1-like isoform X2
500054 Pot1; protection of telomeres protein 1
297758 Terf1; telomeric repeat-binding factor 1
361403 Terf2; telomeric repeat-binding factor 2 isoform 1
290232 Tinf2; TERF1-interacting nuclear factor 2
307861 Terf2ip; telomeric repeat-binding factor 2-interacting protein 1
307798 Acd; adrenocortical dysplasia protein homolog
303238 Ctc1; CST complex subunit CTC1
294025 Stn1; CST complex subunit STN1
360664 Ten1; CST complex subunit TEN1
287522 Smg6; telomerase-binding protein EST1A
681012 Smg5; protein SMG5 isoform X2
314915 RGD1309489; similar to Est1p-like protein B isoform 1
301965 Tert; telomerase reverse transcriptase
64523 Tep1; telomerase protein component 1
499709 Gar1; H/ACA ribonucleoprotein complex subunit 1
287273 Nhp2; NHP2 ribonucleoprotein
691534 Nop10; H/ACA ribonucleoprotein complex subunit 3
170944 Dkc1; H/ACA ribonucleoprotein complex subunit DKC1
171365 Snrpb; small nuclear ribonucleoprotein-associated protein B
291794 Snrpd1; small nuclear ribonucleoprotein Sm D1
292688 Snrpd2l; small nuclear ribonucleoprotein Sm D2
680309 Snrpd2; small nuclear ribonucleoprotein Sm D2
687711 Snrpd3; small nuclear ribonucleoprotein Sm D3
100360682 Snrpe; small nuclear ribonucleoprotein E
108350623 small nuclear ribonucleoprotein F-like
680737 Snrpf; small nuclear ribonucleoprotein F
687679 small nuclear ribonucleoprotein G
681031 Snrpg; small nuclear ribonucleoprotein G
64046 Mre11; double-strand break repair protein MRE11
64012 Rad50; DNA repair protein RAD50
85482 Nbn; nibrin
300711 Atm; serine-protein kinase ATM
290805 Wrn; Werner syndrome ATP-dependent helicase isoform X1
308755 Blm; Bloom syndrome protein isoform X4
360748 Prkdc; DNA-dependent protein kinase catalytic subunit
304719 Ercc4; DNA repair endonuclease XPF isoform X1
103693257 DNA repair endonuclease XPF-like
25591 Parp1; poly [ADP-ribose] polymerase 1
290027 Parp2; poly [ADP-ribose] polymerase 2
300985 Parp3; poly [ADP-ribose] polymerase 3
361046 Parp4; protein mono-ADP-ribosyltransferase PARP4 isoform X1
309512 Tnks2; tankyrase-2
290794 Tnks; tankyrase-1
305963 Pinx1; PIN2/TERF1-interacting telomerase inhibitor 1
362288 Rtel1; regulator of telomere elongation helicase 1
302986 Telo2; telomere length regulation protein TEL2 homolog isoform X1
288920 Trir; uncharacterized protein C19orf43 homolog
295602 Rif1; telomere-associated protein RIF1 isoform X1
367645 Pif1; ATP-dependent DNA helicase PIF1
361162 Purg; purine-rich element-binding protein gamma
287432 Wrap53; telomerase Cajal body protein 1
64550 Top1; DNA topoisomerase 1
300029 Top1mt; DNA topoisomerase I, mitochondrial
360243 Top2a; DNA topoisomerase 2-alpha
361100 Top2b; DNA topoisomerase 2-beta
303194 Top3a; DNA topoisomerase 3-alpha isoform X1
287930 Top3b; DNA topoisomerase 3-beta-1
54304 Ssbp1; single-stranded DNA-binding protein, mitochondrial precursor
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K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K10727 CDT1; chromatin licensing and DNA replication factor 1
K02213 CDC6; cell division control protein 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K10732 GINS1; GINS complex subunit 1
K10733 GINS2; GINS complex subunit 2
K10734 GINS3; GINS complex subunit 3
K10735 GINS4; GINS complex subunit 4
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:3.6.4.12]
K06628 CDC45; cell division control protein 45
K10737 MCM8; DNA helicase MCM8 [EC:3.6.4.12]
K10738 MCM9; DNA helicase MCM9 [EC:3.6.4.12]
K10736 MCM10; minichromosome maintenance protein 10
K15254 HELB; DNA helicase B [EC:3.6.4.12]
K24274 FAM111A; protein FAM111A
K24274 FAM111A; protein FAM111A
K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
K02321 POLA2; DNA polymerase alpha subunit B
K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
K02685 PRI2; DNA primase large subunit
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
K02333 POLG2; DNA polymerase gamma 2
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
K10744 RNASEH2B; ribonuclease H2 subunit B
K10745 RNASEH2C; ribonuclease H2 subunit C
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1; flap endonuclease-1 [EC:3.-.-.-]
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K10749 GMNN; geminin
K10749 GMNN; geminin
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K11109 POT1; protection of telomeres protein 1
K11109 POT1; protection of telomeres protein 1
K11110 TERF1; telomeric repeat-binding factor 1
K11111 TERF2; telomeric repeat-binding factor 2
K11112 TINF2; TERF1-interacting nuclear factor 2
K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
K11114 ACD; adrenocortical dysplasia protein
K23311 CTC1; CST complex subunit CTC1
K23312 STN1; CST complex subunit STN1
K23313 TEN1; CST complex subunit TEN1
K11124 SMG6; protein SMG6 [EC:3.1.-.-]
K11125 SMG5; protein SMG5
K11125 SMG5; protein SMG5
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K11127 TEP1; telomerase protein component 1
K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
K11086 SNRPB; small nuclear ribonucleoprotein B and B'
K11087 SNRPD1; small nuclear ribonucleoprotein D1
K11096 SNRPD2; small nuclear ribonucleoprotein D2
K11096 SNRPD2; small nuclear ribonucleoprotein D2
K11088 SNRPD3; small nuclear ribonucleoprotein D3
K11097 SNRPE; small nuclear ribonucleoprotein E
K11098 SNRPF; small nuclear ribonucleoprotein F
K11098 SNRPF; small nuclear ribonucleoprotein F
K11099 SNRPG; small nuclear ribonucleoprotein G
K11099 SNRPG; small nuclear ribonucleoprotein G
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K10900 WRN; werner syndrome ATP-dependent helicase [EC:3.6.4.12]
K10901 BLM; bloom syndrome protein [EC:3.6.4.12]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10799 TNKS; tankyrase [EC:2.4.2.30]
K10799 TNKS; tankyrase [EC:2.4.2.30]
K11135 PINX1; Pin2-interacting protein X1
K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:3.6.4.12]
K11137 TELO2; telomere length regulation protein
K01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
K11138 RIF1; telomere-associated protein RIF1
K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:3.6.4.12]
K21800 PURG; purine-rich element-binding protein gamma
K23314 WRAP53; telomerase Cajal body protein 1
K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03111 ssb; single-strand DNA-binding protein
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03036 Chromosome and associated proteins [BR:rno03036]
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03400 DNA repair and recombination proteins [BR:rno03400]
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03029 Mitochondrial biogenesis [BR:rno03029]
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09183 Protein families: signaling and cellular processes
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Rattus norvegicus (rat)