Messenger RNA Biogenesis - Rattus norvegicus (rat)

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     KO
 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
     Transport factors
     Surveillance factors
     Factors involved in mRNA localization
     mRNA cycle factors
       Common to processing body (P body) and stress granule
       P-body specific factors
         291604 Dcp2; decapping mRNA 2
         100912393 mRNA-decapping enzyme 2-like
         361109 Dcp1a; decapping mRNA 1A
         500305 Dcp1b; decapping mRNA 1B
         364624 Lsm1; LSM1 homolog, mRNA degradation associated
         684148 Lsm2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
         297455 Lsm3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
         290647 Lsm4; LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
         306222 Lsm5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
         498934 Lsm6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
         100360750 Sm protein F-like
         362829 Lsm7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
         296913 Lsm8; LSM8 homolog, U6 small nuclear RNA associated
         171041 Klc1; kinesin light chain 1
         171549 Klc3; kinesin light chain 3
         316226 Klc4; kinesin light chain 4
         309159 Klc2; kinesin light chain 2
         25017 Myo5a; myosin VA
         25132 Myo5b; myosin Vb
         315820 Myo5c; myosin VC
         64158 Tuba1a; tubulin, alpha 1A
         291287 Tubal3; tubulin, alpha-like 3
         300218 Tuba1c; tubulin, alpha 1C
         316531 Tuba4a; tubulin, alpha 4A
         500319 Tuba3a; tubulin, alpha 3A
         500363 Tuba3b; tubulin, alpha 3B
         500377 Tuba8; tubulin, alpha 8
         500929 Tuba1b; tubulin, alpha 1B
         100909441 tubulin alpha-1C chain-like
         304756 RGD1563709; similar to K-ALPHA-1 protein
         293056 Cpeb1; cytoplasmic polyadenylation element binding protein 1
         303010 Cpeb4; cytoplasmic polyadenylation element binding protein 4
         309510 Cpeb3; cytoplasmic polyadenylation element binding protein 3
         360949 Cpeb2; cytoplasmic polyadenylation element binding protein 2
         691231 Gemin5; gem (nuclear organelle) associated protein 5
         360962 Tacc3; transforming, acidic coiled-coil containing protein 3
         308971 Tnrc6a; trinucleotide repeat containing 6a
         192178 Tnrc6b; trinucleotide repeat containing 6B
         303774 Tnrc6c; trinucleotide repeat containing 6C
         291841 Cnot1; CCR4-NOT transcription complex, subunit 1
         299805 Cnot2; CCR4-NOT transcription complex, subunit 2
         308311 Cnot3; CCR4-NOT transcription complex, subunit 3
         312227 Cnot4; CCR4-NOT transcription complex, subunit 4
         287249 Cnot6; CCR4-NOT transcription complex, subunit 6
         360917 Cnot6l; CCR4-NOT transcription complex, subunit 6-like
         306492 Cnot7; CCR4-NOT transcription complex, subunit 7
         363603 Cnot8; CCR4-NOT transcription complex, subunit 8
         367307 Dis3l2; DIS3-like 3'-5' exoribonuclease 2
         408200 Pan2; PAN2 poly(A) specific ribonuclease subunit
         360760 Pan3; PAN3 poly(A) specific ribonuclease subunit
         170842 Tob1; transducer of ErbB-2.1
         29618 Btg1; BTG anti-proliferation factor 1
         29619 Btg2; BTG anti-proliferation factor 2
         315159 Tob2; transducer of ERBB2, 2
         315650 Btg4; BTG anti-proliferation factor 4
         367975 similar to B-cell translocation gene 1
         54230 Btg3; BTG anti-proliferation factor 3
         305468 Eif4enif1; eukaryotic translation initiation factor 4E nuclear import factor 1
         361736 Patl1; PAT1 homolog 1, processing body mRNA decay factor
         315708 Edc3; enhancer of mRNA decapping 3
         361399 Edc4; enhancer of mRNA decapping 4
         365213 Nanos2; nanos C2HC-type zinc finger 2
         288909 Nanos3; nanos C2HC-type zinc finger 3
         361271 Upf2; UPF2 regulator of nonsense transcripts homolog (yeast)
         313449 Upf3b; UPF3 regulator of nonsense transcripts homolog B (yeast)
         361176 Upf3a; UPF3 regulator of nonsense transcripts homolog A (yeast)
         308901 Trim21; tripartite motif-containing 21
         301042 Trim71; tripartite motif containing 71
         117017 Polr2g; RNA polymerase II subunit G
         54287 Eif2ak2; eukaryotic translation initiation factor 2-alpha kinase 2
         353228 Zar1; zygote arrest 1
         689594 Zar1l; zygote arrest 1-like
         296467 Ythdf1; YTH N(6)-methyladenosine RNA binding protein 1
         313053 Ythdf2; YTH N(6)-methyladenosine RNA binding protein 2
         361920 Ythdf3; YTH N(6)-methyladenosine RNA binding protein 3
K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-] 
K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
K10407 KLC; kinesin light chain 
K10407 KLC; kinesin light chain 
K10407 KLC; kinesin light chain 
K10407 KLC; kinesin light chain 
K10357 MYO5; myosin V 
K10357 MYO5; myosin V 
K10357 MYO5; myosin V 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K07374 TUBA; tubulin alpha 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K13133 GEMIN5; gem associated protein 5 
K14283 TACC3; transforming acidic coiled-coil-containing protein 3 
K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter 
K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
K12615 EDC3; enhancer of mRNA-decapping protein 3 
K12616 EDC4; enhancer of mRNA-decapping protein 4 
K18760 NANOS2; protein nanos 2 
K18761 NANOS3; protein nanos 3 
K14327 UPF2; regulator of nonsense transcripts 2 
K14328 UPF3; regulator of nonsense transcripts 3 
K14328 UPF3; regulator of nonsense transcripts 3 
K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27] 
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1] 
K18762 ZAR1; zygote arrest protein 1 
K18762 ZAR1; zygote arrest protein 1 
K20102 YTHDF; YTH domain-containing family protein 
K20102 YTHDF; YTH domain-containing family protein 
K20102 YTHDF; YTH domain-containing family protein 
       Stress granule specific factors
   mRNA degradation factors
     5'-3' decay
     3'-5' decay
       Core exosome factors
       Exosome cofactors
       TRAMP complex
       Ski complex
       Ccr4-NOT complex
       Pan complex
       Other 3'-5' decay factors
         360464 Parn; poly(A)-specific ribonuclease
         361478 Pnldc1; PARN like, ribonuclease domain containing 1
         310461 Dhx36; DEAH-box helicase 36
         170842 Tob1; transducer of ErbB-2.1
         29618 Btg1; BTG anti-proliferation factor 1
         29619 Btg2; BTG anti-proliferation factor 2
         315159 Tob2; transducer of ERBB2, 2
         315650 Btg4; BTG anti-proliferation factor 4
         367975 similar to B-cell translocation gene 1
         54230 Btg3; BTG anti-proliferation factor 3
         116630 Csf2; colony stimulating factor 2
         310395 Noct; nocturnin
         361159 Eri1; exoribonuclease 1
         691484 Eri2; ERI1 exoribonuclease family member 2
         266605 Dcps; decapping enzyme, scavenger
         306231 Pde12; phosphodiesterase 12
         64831 Ireb2; iron responsive element binding protein 2
K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:3.6.4.13] 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K05427 CSF2; granulocyte-macrophage colony-stimulating factor 
K18764 NOCT; nocturnin [EC:3.1.3.108] 
K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-] 
K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-] 
K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
K22416 IREB2; iron-responsive element-binding protein 2 
     Other degradation factors
 
 Prokaryotic type

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Last updated: September 2, 2020