Mitochondrial Biogenesis - Saccharomyces cerevisiae (budding yeast)

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 Mitochondrial DNA transcription, translation, and replication factors
 
 Mitochondrial protein import machinery
   Endoplasmic reticulum membrane and cytosol
   Outer membrane
   Inter membrane space
   Inner mambrane
     MICOS complex
       YCL057C-A MIC10; Mic10p
       YKR016W MIC60; Mic60p
K17784 MICOS10; MICOS complex subunit MIC10 
K17785 IMMT; MICOS complex subunit MIC60 
     MICOS complex (yeast)
       YCL057C-A MIC10; Mic10p
       YKR016W MIC60; Mic60p
       YBR262C MIC12; Mic12p
       YFR011C MIC19; Mic19p
       YGR235C MIC26; Mic26p
       YNL100W MIC27; Mic27p
K17784 MICOS10; MICOS complex subunit MIC10 
K17785 IMMT; MICOS complex subunit MIC60 
K17787 MIC12; MICOS complex subunit MIC12 
K17788 MIC19; MICOS complex subunit MIC19 
K17786 MIC26; MICOS complex subunit MIC26 
K17789 MIC27; MICOS complex subunit MIC27 
     TIM22 complex
     TIM23 complex
     Mitochondrial calcium uniporter complex
     Other inner membrane factors
   Matrix
 
 Mitochondrial quality control factors
   Regulator of mitochondrial biogenesis
   Mitochondrial respiratory chain complex assembly factors
   Mitochondrial dynamics
     Fission and Fusion factors
     Actin cytoskeleton organization
     Mitochondrial movement
     Retention of mitochondria
     Morphogenesis factors
       YML104C MDM1; Mdm1p
       YHR194W MDM31; Mdm31p
       YOR147W MDM32; Mdm32p
       YAL048C GEM1; ERMES complex Ca(2+)-binding regulatory GTPase GEM1
       YKR016W MIC60; Mic60p
       YGL129C RSM23; mitochondrial 37S ribosomal protein RSM23
       YER125W RSP5; NEDD4 family E3 ubiquitin-protein ligase
       YMR211W DML1; Dml1p
       YDR393W SHE9; She9p
K17887 SNX25; sorting nexin-25 
K17979 MDM31; mitochondrial distribution and morphology protein 31 
K17980 MDM32; mitochondrial distribution and morphology protein 32 
K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-] 
K17785 IMMT; MICOS complex subunit MIC60 
K17408 DAP3; small subunit ribosomal protein S29 
K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] 
K27320 MSTO1; protein misato 
K17983 SHE9; sensitive to high expression protein 9, mitochondrial 
   Mitophagy factors

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Last updated: March 14, 2024