1. Oxidoreductases

   1.1  Acting on the CH-OH group of donors

   1.2  Acting on the aldehyde or oxo group of donors

   1.3  Acting on the CH-CH group of donors

   1.4  Acting on the CH-NH2 group of donors

   1.5  Acting on the CH-NH group of donors

     1.5.1  With NAD+ or NADP+ as acceptor

       1.5.1.1  1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]

       1.5.1.2  pyrroline-5-carboxylate reductase

       1.5.1.3  dihydrofolate reductase

       1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)

       1.5.1.6  formyltetrahydrofolate dehydrogenase

       1.5.1.7  saccharopine dehydrogenase (NAD+, L-lysine-forming)

       1.5.1.8  saccharopine dehydrogenase (NADP+, L-lysine-forming)

       1.5.1.9  saccharopine dehydrogenase (NAD+, L-glutamate-forming)

       1.5.1.10  saccharopine dehydrogenase (NADP+, L-glutamate-forming)

       1.5.1.11  D-octopine dehydrogenase

       1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)

       1.5.1.16  D-lysopine dehydrogenase

       1.5.1.17  alanopine dehydrogenase

       1.5.1.18  ephedrine dehydrogenase

       1.5.1.19  D-nopaline dehydrogenase

       1.5.1.20  methylenetetrahydrofolate reductase [NAD(P)H]

       1.5.1.21  1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)

       1.5.1.22  strombine dehydrogenase

       1.5.1.23  tauropine dehydrogenase

       1.5.1.24  N5-(carboxyethyl)ornithine synthase

       1.5.1.25  thiomorpholine-carboxylate dehydrogenase

       1.5.1.26  beta-alanopine dehydrogenase

       1.5.1.27  1,2-dehydroreticulinium reductase (NADPH)

       1.5.1.28  opine dehydrogenase

       1.5.1.30  flavin reductase (NADPH)

       1.5.1.31  berberine reductase

       1.5.1.32  vomilenine reductase

       1.5.1.33  pteridine reductase

       1.5.1.34  6,7-dihydropteridine reductase

       1.5.1.36  flavin reductase (NADH)

       1.5.1.37  FAD reductase (NADH)

       1.5.1.38  FMN reductase (NADPH)

       1.5.1.39  FMN reductase [NAD(P)H]

       1.5.1.40  8-hydroxy-5-deazaflavin:NADPH oxidoreductase

       1.5.1.41  riboflavin reductase [NAD(P)H]

       1.5.1.42  FMN reductase (NADH)

       1.5.1.43  carboxynorspermidine synthase

       1.5.1.44  festuclavine dehydrogenase

       1.5.1.45  FAD reductase [NAD(P)H]

       1.5.1.46  agroclavine dehydrogenase

       1.5.1.47  dihydromethanopterin reductase [NAD(P)+]

       1.5.1.48  2-methyl-1-pyrroline reductase

       1.5.1.49  1-pyrroline-2-carboxylate reductase [NAD(P)H]

       1.5.1.50  dihydromonapterin reductase

       1.5.1.51  N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase

       1.5.1.52  staphylopine dehydrogenase

       1.5.1.53  methylenetetrahydrofolate reductase (NADPH)

       1.5.1.54  methylenetetrahydrofolate reductase (NADH)

       1.5.1.55  carboxyaminopropylagmatine dehydrogenase

     1.5.3  With oxygen as acceptor

     1.5.4  With a disulfide as acceptor

     1.5.5  With a quinone or similar compound as acceptor

     1.5.7  With an iron-sulfur protein as acceptor

     1.5.8  With a flavin or flavoprotein as acceptor

     1.5.98  With other, known, physiological acceptors

     1.5.99  With unknown physiological acceptors

   1.6  Acting on NADH or NADPH

   1.7  Acting on other nitrogenous compounds as donors

   1.8  Acting on a sulfur group of donors

   1.9  Acting on a heme group of donors

   1.10  Acting on diphenols and related substances as donors

   1.11  Acting on a peroxide as acceptor

   1.12  Acting on hydrogen as donor

   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)

   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen

   1.15  Acting on superoxide as acceptor

   1.16  Oxidizing metal ions

   1.17  Acting on CH or CH2 groups

   1.18  Acting on iron-sulfur proteins as donors

   1.19  Acting on reduced flavodoxin as donor

   1.20  Acting on phosphorus or arsenic in donors

   1.21  Catalysing the reaction X-H + Y-H = X-Y

   1.23  Reducing C-O-C group as acceptor

   1.97  Other oxidoreductases

 2. Transferases

 3. Hydrolases

   3.1  Acting on ester bonds

   3.2  Glycosylases

   3.3  Acting on ether bonds

   3.4  Acting on peptide bonds (peptidases)

   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds

     3.5.1  In linear amides

     3.5.2  In cyclic amides

     3.5.3  In linear amidines

     3.5.4  In cyclic amidines

       3.5.4.1  cytosine deaminase

       3.5.4.2  adenine deaminase

       3.5.4.3  guanine deaminase

       3.5.4.4  adenosine deaminase

       3.5.4.5  cytidine deaminase

       3.5.4.6  AMP deaminase

       3.5.4.7  ADP deaminase

       3.5.4.8  aminoimidazolase

       3.5.4.9  methenyltetrahydrofolate cyclohydrolase

       3.5.4.10  IMP cyclohydrolase

       3.5.4.11  pterin deaminase

       3.5.4.12  dCMP deaminase

       3.5.4.13  dCTP deaminase

       3.5.4.15  guanosine deaminase

       3.5.4.16  GTP cyclohydrolase I

       3.5.4.17  adenosine-phosphate deaminase

       3.5.4.18  ATP deaminase

       3.5.4.19  phosphoribosyl-AMP cyclohydrolase

       3.5.4.20  pyrithiamine deaminase

       3.5.4.21  creatinine deaminase

       3.5.4.22  1-pyrroline-4-hydroxy-2-carboxylate deaminase

       3.5.4.23  blasticidin-S deaminase

       3.5.4.24  sepiapterin deaminase

       3.5.4.25  GTP cyclohydrolase II

       3.5.4.26  diaminohydroxyphosphoribosylaminopyrimidine deaminase

       3.5.4.27  methenyltetrahydromethanopterin cyclohydrolase

       3.5.4.28  S-adenosylhomocysteine deaminase

       3.5.4.29  GTP cyclohydrolase IIa

       3.5.4.30  dCTP deaminase (dUMP-forming)

       3.5.4.31  S-methyl-5'-thioadenosine deaminase

       3.5.4.32  8-oxoguanine deaminase

       3.5.4.33  tRNA(adenine34) deaminase

       3.5.4.34  tRNAAla(adenine37) deaminase

       3.5.4.35  tRNA(cytosine8) deaminase

       3.5.4.36  mRNA(cytosine6666) deaminase

       3.5.4.37  double-stranded RNA adenine deaminase

       3.5.4.38  single-stranded DNA cytosine deaminase

       3.5.4.39  GTP cyclohydrolase IV

       3.5.4.40  aminodeoxyfutalosine deaminase

       3.5.4.41  5'-deoxyadenosine deaminase

       3.5.4.42  N-isopropylammelide isopropylaminohydrolase

       3.5.4.43  hydroxydechloroatrazine ethylaminohydrolase

       3.5.4.44  ectoine hydrolase

       3.5.4.45  melamine deaminase

       3.5.4.46  cAMP deaminase

     3.5.5  In nitriles

     3.5.99  In other compounds

   3.6  Acting on acid anhydrides

   3.7  Acting on carbon-carbon bonds

   3.8  Acting on halide bonds

   3.9  Acting on phosphorus-nitrogen bonds

   3.10  Acting on sulfur-nitrogen bonds

   3.11  Acting on carbon-phosphorus bonds

   3.12  Acting on sulfur-sulfur bonds

   3.13  Acting on carbon-sulfur bonds

 4. Lyases

 5. Isomerases

 6. Ligases

 7. Translocases