KEGG Orthology (KO) - Streptococcus pneumoniae TCH8431/19A (serotype 19A)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system [PATH:snc02020]
       HMPREF0837_10080 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_10079 response regulator receiver domain protein
       HMPREF0837_10081 putative Phosphate-binding protein PstS 2
       HMPREF0837_11147 pstS; phosphate binding protein
       HMPREF0837_10253 trypsin
       HMPREF0837_11276 PAS domain S-box protein
       HMPREF0837_11275 response regulator receiver domain protein
       HMPREF0837_10255 dnaA; chromosomal replication initiator protein DnaA
       HMPREF0837_10370 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_10369 saeR; response regulator SaeR
       HMPREF0837_10180 dltA; D-alanine--poly(phosphoribitol) ligase, subunit 1
       HMPREF0837_10179 MBOAT family protein
       HMPREF0837_10178 dltC; D-alanine--poly(phosphoribitol) ligase, subunit 2
       HMPREF0837_10177 DltD central region
       HMPREF0837_11693 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_11694 response regulator receiver domain protein
       HMPREF0837_10919 serine-type D-Ala-D-Ala carboxypeptidase
       HMPREF0837_10821 hypothetical protein
       HMPREF0837_10820 LytTr DNA-binding domain protein
       HMPREF0837_10331 ABC-type bacteriocin transporter
       HMPREF0837_10332 mesE; bacteriocin secretion accessory protein
       HMPREF0837_10251 comC; competence-stimulating peptide type 1
       HMPREF0837_10250 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_10249 LytTr DNA-binding domain protein
       HMPREF0837_10002 comX; transcriptional regulator ComX1
       HMPREF0837_10302 comX; transcriptional regulator ComX1
       HMPREF0837_10298 hypothetical protein
       HMPREF0837_12270 histidine kinase
       HMPREF0837_12269 response regulator receiver domain protein
       HMPREF0837_10684 histidine kinase
       HMPREF0837_10685 response regulator receiver domain protein
       HMPREF0837_10797 glnA; glutamine synthetase, type I
       HMPREF0837_10466 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_10954 cache domain protein
       HMPREF0837_10467 response regulator receiver domain protein
       HMPREF0837_10023 low molecular weight phosphotyrosine protein phosphatase
       HMPREF0837_10647 PHP domain protein
       HMPREF0837_10656 UDP-N-acetylglucosamine 2-epimerase
K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
K02040 pstS; phosphate transport system substrate-binding protein
K02040 pstS; phosphate transport system substrate-binding protein
K04771 degP; serine protease Do [EC:3.4.21.107]
K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
K07668 vicR; two-component system, OmpR family, response regulator VicR
K02313 dnaA; chromosomal replication initiator protein
K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
K10682 saeR; two-component system, OmpR family, response regulator SaeR
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K03739 dltB; membrane protein involved in D-alanine export
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K03740 dltD; D-alanine transfer protein
K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
K14983 ciaR; two-component system, OmpR family, response regulator CiaR
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07707 agrA; two-component system, LytTR family, response regulator AgrA
K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-]
K12293 comB; competence factor transport accessory protein ComB
K12415 comC; competence-stimulating peptide
K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]
K12295 comE; two-component system, LytTR family, response regulator ComE
K12296 comX1_2; competence protein ComX
K12296 comX1_2; competence protein ComX
K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
K07693 desR; two-component system, NarL family, response regulator DesR
K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
K11618 liaR; two-component system, NarL family, response regulator LiaR
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
K07720 yesN; two-component system, response regulator YesN
K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]
K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]
K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04010 MAPK signaling pathway
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway
     04310 Wnt signaling pathway
     04330 Notch signaling pathway
     04340 Hedgehog signaling pathway
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway
     04371 Apelin signaling pathway
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway
     04020 Calcium signaling pathway
     04070 Phosphatidylinositol signaling system
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
     02024 Quorum sensing [PATH:snc02024]
       HMPREF0837_10642 luxS; S-ribosylhomocysteinase LuxS
       HMPREF0837_12044 trpE; anthranilate synthase component I
       HMPREF0837_12043 glutamine amidotransferase
       HMPREF0837_11942 3-deoxy-7-phosphoheptulonate synthase
       HMPREF0837_11943 putative 3-deoxy-7-phosphoheptulonate synthase
       HMPREF0837_11032 receptor family ligand-binding protein
       HMPREF0837_11033 branched-chain amino acid ABC transporter
       HMPREF0837_11034 branched-chain amino acid ABC transporter
       HMPREF0837_11035 ABC transporter
       HMPREF0837_11036 ABC transporter
       HMPREF0837_10478 ribD; riboflavin biosynthesis protein RibD
       HMPREF0837_10821 hypothetical protein
       HMPREF0837_10820 LytTr DNA-binding domain protein
       HMPREF0837_12158 Thiol-activated cytolysin
       HMPREF0837_10251 comC; competence-stimulating peptide type 1
       HMPREF0837_10331 ABC-type bacteriocin transporter
       HMPREF0837_10332 mesE; bacteriocin secretion accessory protein
       HMPREF0837_10250 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_10249 LytTr DNA-binding domain protein
       HMPREF0837_10832 blpL; immunity protein BlpL
       HMPREF0837_11693 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein
       HMPREF0837_11694 response regulator receiver domain protein
       HMPREF0837_11762 ABC transporter
       HMPREF0837_12120 amiA; oligopeptide-binding protein AmiA
       HMPREF0837_12119 ABC transporter
       HMPREF0837_12118 ABC transporter
       HMPREF0837_12117 ABC transporter
       HMPREF0837_12116 ABC transporter
       HMPREF0837_12258 hypothetical protein
       HMPREF0837_10002 comX; transcriptional regulator ComX1
       HMPREF0837_10302 comX; transcriptional regulator ComX1
       HMPREF0837_10823 bacteriocin-type signal sequence
       HMPREF0837_10826 peptidase
       HMPREF0837_10825 ABC transporter
       HMPREF0837_10407 peptidase
       HMPREF0837_10824 mesE; bacteriocin secretion accessory protein
       HMPREF0837_10124 transcriptional activator
       HMPREF0837_11366 transcriptional activator
       HMPREF0837_10664 ABC transporter
       HMPREF0837_11634 hypothetical protein
       HMPREF0837_11310 lacD; tagatose-bisphosphate aldolase
       HMPREF0837_10037 membrane protein insertase
       HMPREF0837_12244 membrane protein insertase
       HMPREF0837_10004 secE; preprotein translocase, SecE subunit
       HMPREF0837_11515 secG; preprotein translocase, SecG subunit
       HMPREF0837_10541 secY; preprotein translocase, SecY subunit
       HMPREF0837_10024 yajC; preprotein translocase, YajC subunit
       HMPREF0837_10629 yajC; preprotein translocase, YajC subunit
       HMPREF0837_11944 secA; preprotein translocase, SecA subunit
       HMPREF0837_11257 ftsY; signal recognition particle-docking protein FtsY
       HMPREF0837_11213 ffh; signal recognition particle protein
K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K01999 livK; branched-chain amino acid transport system substrate-binding protein
K01997 livH; branched-chain amino acid transport system permease protein
K01998 livM; branched-chain amino acid transport system permease protein
K01995 livG; branched-chain amino acid transport system ATP-binding protein
K01996 livF; branched-chain amino acid transport system ATP-binding protein
K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07707 agrA; two-component system, LytTR family, response regulator AgrA
K11031 slo; thiol-activated cytolysin
K12415 comC; competence-stimulating peptide
K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-]
K12293 comB; competence factor transport accessory protein ComB
K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]
K12295 comE; two-component system, LytTR family, response regulator ComE
K20341 blpL; immunity protein
K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
K14983 ciaR; two-component system, OmpR family, response regulator CiaR
K15580 oppA; oligopeptide transport system substrate-binding protein
K15580 oppA; oligopeptide transport system substrate-binding protein
K15581 oppB; oligopeptide transport system permease protein
K15582 oppC; oligopeptide transport system permease protein
K15583 oppD; oligopeptide transport system ATP-binding protein
K10823 oppF; oligopeptide transport system ATP-binding protein
K20342 comR; HTH-type transcriptional regulator, regulator for ComX
K12296 comX1_2; competence protein ComX
K12296 comX1_2; competence protein ComX
K20343 blpC; peptide pheromone BlpC
K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter
K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter
K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter
K20345 blpB; membrane fusion protein, peptide pheromone/bacteriocin exporter
K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
K03217 yidC; YidC/Oxa1 family membrane protein insertase
K03217 yidC; YidC/Oxa1 family membrane protein insertase
K03073 secE; preprotein translocase subunit SecE
K03075 secG; preprotein translocase subunit SecG
K03076 secY; preprotein translocase subunit SecY
K03210 yajC; preprotein translocase subunit YajC
K03210 yajC; preprotein translocase subunit YajC
K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
K03110 ftsY; fused signal recognition particle receptor
K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
     05111 Biofilm formation - Vibrio cholerae
     02025 Biofilm formation - Pseudomonas aeruginosa
     02026 Biofilm formation - Escherichia coli
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:snc03000]
       HMPREF0837_11316 transcriptional regulator
       HMPREF0837_11618 transcriptional regulator
       HMPREF0837_10110 malR; HTH-type transcriptional regulator MalR
       HMPREF0837_12268 ccpA; catabolite control protein A
       HMPREF0837_12026 transcriptional regulator
       HMPREF0837_12077 transcriptional regulator
       HMPREF0837_11968 transcriptional regulator
       HMPREF0837_12110 treR; trehalose operon repressor
       HMPREF0837_10015 UbiC transcription regulator-associated domain protein
       HMPREF0837_11097 UbiC transcription regulator-associated domain protein
       HMPREF0837_12086 transcriptional regulator
       HMPREF0837_10796 transcriptional regulator
       HMPREF0837_12079 transcriptional regulator
       HMPREF0837_12136 DNA-binding helix-turn-helix protein
       HMPREF0837_11878 FeoA domain protein
       HMPREF0837_11703 transcriptional regulator
       HMPREF0837_10389 transcriptional regulator
       HMPREF0837_12130 biotin--[acetyl-CoA-carboxylase] ligase
       HMPREF0837_12258 hypothetical protein
       HMPREF0837_10124 transcriptional activator
       HMPREF0837_11366 transcriptional activator
       HMPREF0837_11392 CoA binding domain protein
       HMPREF0837_11819 codY; GTP-sensing transcriptional pleiotropic repressor CodY
       HMPREF0837_11448 hypothetical protein
       HMPREF0837_10635 DNA-binding helix-turn-helix protein
       HMPREF0837_10119 DNA-binding helix-turn-helix protein
       HMPREF0837_11122 DNA-binding helix-turn-helix protein
       HMPREF0837_11860 HTH domain protein
       HMPREF0837_10869 PRD domain protein
       HMPREF0837_10027 PRD domain protein
       HMPREF0837_10254 ParB-like protein
       HMPREF0837_11311 PRD domain protein
       HMPREF0837_10075 argR; arginine repressor
       HMPREF0837_11296 arginine repressor
       HMPREF0837_11597 arginine repressor
       HMPREF0837_10808 hrcA; heat-inducible transcription repressor HrcA
       HMPREF0837_11000 TENA/THI-4 family protein
       HMPREF0837_11006 TENA/THI-4 family protein
       HMPREF0837_10209 transcriptional repressor of CtsR
       HMPREF0837_11579 PspC domain protein
       HMPREF0837_11223 phosphoribosyl transferase domain protein
       HMPREF0837_11955 nrdR; transcriptional regulator NrdR
       HMPREF0837_12247 purR; pur operon repressor PurR
       HMPREF0837_10002 comX; transcriptional regulator ComX1
       HMPREF0837_10302 comX; transcriptional regulator ComX1
K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor
K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
K02529 lacI; LacI family transcriptional regulator
K02529 lacI; LacI family transcriptional regulator
K02529 lacI; LacI family transcriptional regulator
K02529 lacI; LacI family transcriptional regulator
K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor
K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor
K03492 ydhQ; GntR family transcriptional regulator
K03710 K03710; GntR family transcriptional regulator
K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
K21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator
K23779 sutR; XRE family transcriptional regulator, regulator of sulfur utilization
K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
K10947 padR; PadR family transcriptional regulator, regulatory protein PadR
K10947 padR; PadR family transcriptional regulator, regulatory protein PadR
K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
K20342 comR; HTH-type transcriptional regulator, regulator for ComX
K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
K01926 rex; redox-sensing transcriptional repressor
K03706 codY; transcriptional pleiotropic repressor
K07727 K07727; putative transcriptional regulator
K07729 K07729; putative transcriptional regulator
K07729 K07729; putative transcriptional regulator
K07729 K07729; putative transcriptional regulator
K02538 manR; activator of the mannose operon, transcriptional antiterminator
K03488 licT; beta-glucoside operon transcriptional antiterminator
K03493 bglG1; transcriptional antiterminator
K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
K02531 lacT; transcriptional antiterminator
K03402 argR; transcriptional regulator of arginine metabolism
K03402 argR; transcriptional regulator of arginine metabolism
K03402 argR; transcriptional regulator of arginine metabolism
K03705 hrcA; heat-inducible transcriptional repressor
K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
K03708 ctsR; transcriptional regulator of stress and heat shock response
K03973 pspC; phage shock protein C
K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
K07738 nrdR; transcriptional repressor NrdR
K09685 purR; purine operon repressor
K12296 comX1_2; competence protein ComX
K12296 comX1_2; competence protein ComX
     03021 Transcription machinery [BR:snc03021]
     03019 Messenger RNA biogenesis [BR:snc03019]
     03041 Spliceosome
     03011 Ribosome [BR:snc03011]
     03009 Ribosome biogenesis [BR:snc03009]
     03016 Transfer RNA biogenesis [BR:snc03016]
     03012 Translation factors [BR:snc03012]
     03110 Chaperones and folding catalysts [BR:snc03110]
     04131 Membrane trafficking [BR:snc04131]
     04121 Ubiquitin system
     03051 Proteasome
     03032 DNA replication proteins [BR:snc03032]
     03036 Chromosome and associated proteins [BR:snc03036]
     03400 DNA repair and recombination proteins [BR:snc03400]
     03029 Mitochondrial biogenesis [BR:snc03029]
 
   09183 Protein families: signaling and cellular processes
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

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Last updated: August 6, 2020