KEGG Orthology (KO) - Streptococcus salivarius HSISS4

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
     00410 beta-Alanine metabolism
     00430 Taurine and hypotaurine metabolism [PATH:ssah00430]
     00440 Phosphonate and phosphinate metabolism
     00450 Selenocompound metabolism [PATH:ssah00450]
     00460 Cyanoamino acid metabolism [PATH:ssah00460]
     00470 D-Amino acid metabolism [PATH:ssah00470]
       HSISS4_01633 alr; Alanine racemase
       HSISS4_01488 ddl; D-alanine--D-alanine ligase
       HSISS4_01111 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1
       HSISS4_01109 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2
       HSISS4_00203 glr; Glutamate racemase
       HSISS4_00683 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase
       HSISS4_00200 lysA; Diaminopimelate decarboxylase
K01775 alr; alanine racemase [EC:5.1.1.1]
K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K01776 murI; glutamate racemase [EC:5.1.1.3]
K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
     00480 Glutathione metabolism [PATH:ssah00480]
 
   09107 Glycan biosynthesis and metabolism
     00510 N-Glycan biosynthesis
     00513 Various types of N-glycan biosynthesis
     00512 Mucin type O-glycan biosynthesis
     00515 Mannose type O-glycan biosynthesis
     00514 Other types of O-glycan biosynthesis
     00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
     00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
     00533 Glycosaminoglycan biosynthesis - keratan sulfate
     00531 Glycosaminoglycan degradation
     00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
     00601 Glycosphingolipid biosynthesis - lacto and neolacto series
     00603 Glycosphingolipid biosynthesis - globo and isoglobo series
     00604 Glycosphingolipid biosynthesis - ganglio series
     00511 Other glycan degradation [PATH:ssah00511]
     00540 Lipopolysaccharide biosynthesis
     00542 O-Antigen repeat unit biosynthesis [PATH:ssah00542]
     00541 O-Antigen nucleotide sugar biosynthesis [PATH:ssah00541]
     00550 Peptidoglycan biosynthesis [PATH:ssah00550]
     00552 Teichoic acid biosynthesis [PATH:ssah00552]
       HSISS4_00126 uppP; Undecaprenyl-diphosphatase
       HSISS4_00216 Membrane-associated phospholipid phosphatase
       HSISS4_00129 rgpG; Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase
       HSISS4_00330 Lipopolysaccharide biosynthesis protein
       HSISS4_01314 Poly(glycerol-phosphate) alpha-glucosyltransferase GftA
       HSISS4_01542 hypothetical protein
       HSISS4_01111 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1
       HSISS4_01109 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2
       HSISS4_01110 dltB; D-alanyl transfer protein DltB
       HSISS4_01108 dltD; Poly(glycerophosphate chain) D-alanine transfer protein DltD
       HSISS4_00267 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily F2
       HSISS4_00565 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily F1
       HSISS4_00878 epsA; Exopolysaccharide biosynthesis transcriptional activator EpsA
       HSISS4_00553 Lipoteichoic acid synthase LtaS Type IIc
       HSISS4_00487 Glycosyltransferase LafA, responsible for the formation of Glc-DAG
K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
K00712 tagE; poly(glycerol-phosphate) alpha-glucosyltransferase [EC:2.4.1.52]
K00712 tagE; poly(glycerol-phosphate) alpha-glucosyltransferase [EC:2.4.1.52]
K00712 tagE; poly(glycerol-phosphate) alpha-glucosyltransferase [EC:2.4.1.52]
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K03739 dltB; membrane protein involved in D-alanine export
K03740 dltD; D-alanine transfer protein
K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]
K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
     00571 Lipoarabinomannan (LAM) biosynthesis
     00572 Arabinogalactan biosynthesis - Mycobacterium
     00543 Exopolysaccharide biosynthesis [PATH:ssah00543]
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system [PATH:ssah02020]
       HSISS4_00939 pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein PstS
       HSISS4_01902 htrA; Serine protease, DegP/HtrA, do-like
       HSISS4_00837 Two-component sensor kinase SA14-24
       HSISS4_00836 Two-component response regulator SA14-24
       HSISS4_01269 Choline binding protein A
       HSISS4_00001 dnaA; Chromosomal replication initiator protein DnaA
       HSISS4_01190 ABC transporter permease protein
       HSISS4_01191 ABC transporter ATP-binding protein
       HSISS4_01192 Histidine kinase
       HSISS4_01193 Two-component response regulator
       HSISS4_01111 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1
       HSISS4_01110 dltB; D-alanyl transfer protein DltB
       HSISS4_01109 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2
       HSISS4_01108 dltD; Poly(glycerophosphate chain) D-alanine transfer protein DltD
       HSISS4_01289 L-O-lysylphosphatidylglycerol synthase
       HSISS4_00711 L-O-lysylphosphatidylglycerol synthase
       HSISS4_01096 Two component system sensor histidine kinase CiaH
       HSISS4_01097 Two component system response regulator CiaR
       HSISS4_00093 dacB; D-alanyl-D-alanine carboxypeptidase
       HSISS4_00381 cbpD3; D-alanyl-D-alanine carboxypeptidase
       HSISS4_00375 putative choline binding protein
       HSISS4_00247 csrS; Transmembrane histidine kinase CsrS
       HSISS4_00246 csrR; Response regulator CsrR
       HSISS4_01035 Sensor histidine kinase
       HSISS4_01036 Response regulator
       HSISS4_01039 hypothetical protein
       HSISS4_01038 hypothetical protein
       HSISS4_01037 hypothetical protein
       HSISS4_01612 Accessory regulator protein C
       HSISS4_01613 hypothetical protein
       HSISS4_01717 Histidine kinase of the competence regulon ComD
       HSISS4_01719 hypothetical protein
       HSISS4_00379 Histidine kinase of the competence regulon ComD
       HSISS4_01446 Histidine kinase of the competence regulon ComD
       HSISS4_00909 Histidine kinase of the competence regulon ComD
       HSISS4_01716 Sensory transduction protein kinase
       HSISS4_01718 putative histidine kinase
       HSISS4_00910 hypothetical protein
       HSISS4_01715 Response regulator of the competence regulon ComE
       HSISS4_00378 response regulator
       HSISS4_01447 response regulator
       HSISS4_00102 comX; Competence-specific sigma factor ComX
       HSISS4_00010 hypothetical protein
       HSISS4_01178 Sensor histidine kinase
       HSISS4_01177 DNA-binding response regulator, LuxR family
       HSISS4_01345 vraS; Sensor histidine kinase VraS
       HSISS4_01344 vraR; Two component transcriptional regulator VraR
       HSISS4_01346 Transporter associated with VraSR
       HSISS4_00417 gnlB; Nitrogen regulatory protein P-II
       HSISS4_01683 gnlA; Glutamine synthetase type I
       HSISS4_01828 Low molecular weight protein tyrosine phosphatase
K02040 pstS; phosphate transport system substrate-binding protein
K04771 degP; serine protease Do [EC:3.4.21.107]
K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
K07668 vicR; two-component system, OmpR family, response regulator VicR
K00689 E2.4.1.5; dextransucrase [EC:2.4.1.5]
K02313 dnaA; chromosomal replication initiator protein
K19084 braE; bacitracin transport system permease protein
K19083 braD; bacitracin transport system ATP-binding protein
K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K03739 dltB; membrane protein involved in D-alanine export
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K03740 dltD; D-alanine transfer protein
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
K14983 ciaR; two-component system, OmpR family, response regulator CiaR
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
K18941 arlR; two-component system, OmpR family, response regulator ArlR
K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR
K20490 nisF; lantibiotic transport system ATP-binding protein
K20491 nisE; lantibiotic transport system permease protein
K20492 nisG; lantibiotic transport system permease protein
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07707 agrA; two-component system, LytTR family, response regulator AgrA
K07707 agrA; two-component system, LytTR family, response regulator AgrA
K07707 agrA; two-component system, LytTR family, response regulator AgrA
K12296 comX1_2; competence protein ComX
K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
K07693 desR; two-component system, NarL family, response regulator DesR
K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
K11618 liaR; two-component system, NarL family, response regulator LiaR
K11622 liaF; lia operon protein LiaF
K04751 glnB; nitrogen regulatory protein P-II 1
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
     04010 MAPK signaling pathway
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway
     04330 Notch signaling pathway
     04340 Hedgehog signaling pathway
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway
     04371 Apelin signaling pathway
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway
     04020 Calcium signaling pathway
     04070 Phosphatidylinositol signaling system
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
     01501 beta-Lactam resistance [PATH:ssah01501]
     01502 Vancomycin resistance [PATH:ssah01502]
     01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:ssah01503]
       HSISS4_00855 mur1B; N-acetylmuramoyl-L-alanine amidase
       HSISS4_00916 N-acetylmuramoyl-L-alanine amidase
       HSISS4_01902 htrA; Serine protease, DegP/HtrA, do-like
       HSISS4_00431 ppiA; Peptidyl-prolyl cis-trans isomerase
       HSISS4_01111 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1
       HSISS4_01110 dltB; D-alanyl transfer protein DltB
       HSISS4_01109 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2
       HSISS4_01108 dltD; Poly(glycerophosphate chain) D-alanine transfer protein DltD
       HSISS4_01289 L-O-lysylphosphatidylglycerol synthase
       HSISS4_00711 L-O-lysylphosphatidylglycerol synthase
K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K04771 degP; serine protease Do [EC:3.4.21.107]
K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K03739 dltB; membrane protein involved in D-alanine export
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K03740 dltD; D-alanine transfer protein
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
     02000 Transporters [BR:ssah02000]
     02044 Secretion system [BR:ssah02044]
     02042 Bacterial toxins [BR:ssah02042]
     02022 Two-component system [BR:ssah02022]
     02035 Bacterial motility proteins [BR:ssah02035]
     03037 Cilium and associated proteins
     04812 Cytoskeleton proteins [BR:ssah04812]
     04147 Exosome [BR:ssah04147]
     02048 Prokaryotic defense system [BR:ssah02048]
     04030 G protein-coupled receptors
     04050 Cytokine receptors
     04054 Pattern recognition receptors
     03310 Nuclear receptors
     04040 Ion channels
     04031 GTP-binding proteins
     04052 Cytokines and neuropeptides
     04515 Cell adhesion molecules
     04090 CD molecules
     01504 Antimicrobial resistance genes [BR:ssah01504]
       HSISS4_00572 ATPase components of ABC transporters with duplicated ATPase domains
       HSISS4_00571 Macrolide-efflux protein
       HSISS4_00675 hypothetical protein
       HSISS4_00093 dacB; D-alanyl-D-alanine carboxypeptidase
       HSISS4_00381 cbpD3; D-alanyl-D-alanine carboxypeptidase
       HSISS4_00375 putative choline binding protein
       HSISS4_01111 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1
       HSISS4_01110 dltB; D-alanyl transfer protein DltB
       HSISS4_01109 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2
       HSISS4_01108 dltD; Poly(glycerophosphate chain) D-alanine transfer protein DltD
       HSISS4_01289 L-O-lysylphosphatidylglycerol synthase
       HSISS4_00711 L-O-lysylphosphatidylglycerol synthase
       HSISS4_01299 Transcriptional regulator
K18231 msr; macrolide transport system ATP-binding/permease protein
K08217 mef; MFS transporter, DHA3 family, macrolide efflux protein
K17836 penP; beta-lactamase class A [EC:3.5.2.6]
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K03739 dltB; membrane protein involved in D-alanine export
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K03740 dltD; D-alanine transfer protein
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
K18909 mepR; MarR family transcriptional regulator, repressor for mepA
     00535 Proteoglycans
     00536 Glycosaminoglycan binding proteins
     00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
     04091 Lectins
     04990 Domain-containing proteins not elsewhere classified
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

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Last updated: April 22, 2024