Search BRITE hierarchies
KEGG Orthology (KO) [BR:cjc00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway [PATH:cjc04010]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04310 Wnt signaling pathway [PATH:cjc04310]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04370 VEGF signaling pathway [PATH:cjc04370]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04020 Calcium signaling pathway [PATH:cjc04020]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04022 cGMP-PKG signaling pathway [PATH:cjc04022]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis [PATH:cjc04114]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04218 Cellular senescence [PATH:cjc04218]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway [PATH:cjc04625]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04650 Natural killer cell mediated cytotoxicity [PATH:cjc04650]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04660 T cell receptor signaling pathway [PATH:cjc04660]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04658 Th1 and Th2 cell differentiation [PATH:cjc04658]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04659 Th17 cell differentiation [PATH:cjc04659]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04662 B cell receptor signaling pathway [PATH:cjc04662]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09152 Endocrine system
04922 Glucagon signaling pathway [PATH:cjc04922]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04921 Oxytocin signaling pathway [PATH:cjc04921]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04924 Renin secretion [PATH:cjc04924]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09156 Nervous system
04724 Glutamatergic synapse [PATH:cjc04724]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04728 Dopaminergic synapse [PATH:cjc04728]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04720 Long-term potentiation [PATH:cjc04720]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09158 Development and regeneration
04360 Axon guidance [PATH:cjc04360]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
04380 Osteoclast differentiation [PATH:cjc04380]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:cjc05235]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection [PATH:cjc05166]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
05170 Human immunodeficiency virus 1 infection [PATH:cjc05170]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
05163 Human cytomegalovirus infection [PATH:cjc05163]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:cjc05167]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09171 Infectious disease: bacterial
05152 Tuberculosis [PATH:cjc05152]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09164 Neurodegenerative disease
05010 Alzheimer disease [PATH:cjc05010]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
05014 Amyotrophic lateral sclerosis [PATH:cjc05014]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
05020 Prion disease [PATH:cjc05020]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
05022 Pathways of neurodegeneration - multiple diseases [PATH:cjc05022]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09165 Substance dependence
05031 Amphetamine addiction [PATH:cjc05031]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09166 Cardiovascular disease
05417 Lipid and atherosclerosis [PATH:cjc05417]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:cjc01009]
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Enzymes [BR:cjc01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Protein phosphatases and associated proteins [BR:cjc01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Catalytic subunits
100386369 PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
[ BRITE | KEGG2 | KEGG ]