Search BRITE hierarchies

KEGG Orthology (KO) [BR:cjc00001]
  09120 Genetic Information Processing
    09123 Folding, sorting and degradation
      04120 Ubiquitin mediated proteolysis [PATH:cjc04120]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
    09124 Replication and repair
      03440 Homologous recombination [PATH:cjc03440]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
      03460 Fanconi anemia pathway [PATH:cjc03460]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
  09130 Environmental Information Processing
    09132 Signal transduction
      04151 PI3K-Akt signaling pathway [PATH:cjc04151]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
  09160 Human Diseases
    09161 Cancer: overview
      05206 MicroRNAs in cancer [PATH:cjc05206]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
    09162 Cancer: specific types
      05224 Breast cancer [PATH:cjc05224]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
    09176 Drug resistance: antineoplastic
      01524 Platinum drug resistance [PATH:cjc01524]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
  09180 Brite Hierarchies
    09181 Protein families: metabolism
      01009 Protein phosphatases and associated proteins [BR:cjc01009]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
    09182 Protein families: genetic information processing
      04121 Ubiquitin system [BR:cjc04121]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
      03036 Chromosome and associated proteins [BR:cjc03036]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
      03400 DNA repair and recombination proteins [BR:cjc03400]
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]

Enzymes [BR:cjc01000]
  2. Transferases
    2.3  Acyltransferases
      2.3.2  Aminoacyltransferases
        2.3.2.27  RING-type E3 ubiquitin transferase
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 

Protein phosphatases and associated proteins [BR:cjc01009]
  Protein serine/threonine phosphatases
    Phosphoprotein phosphatases (PPPs)
      Protein phosphatase-1
        PP1-interacting proteins (PIPs)
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 

Ubiquitin system [BR:cjc04121]
  Ubiquitin ligases (E3)
    Single Ring-finger type E3
      Other single Ring-finger type E3
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
    Multi subunit Ring-finger type E3
      BRCC complex
        100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 

Chromosome and associated proteins [BR:cjc03036]
  Eukaryotic type
    Centrosome formation proteins
      Centrosome duplication proteins
        Regulators of centriole replication
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 

DNA repair and recombination proteins [BR:cjc03400]
  Eukaryotic type
    DSBR (double strand breaks repair)
      HR (homologous recombination)
        BRCA1-core complex
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
        BRCA1-A complex
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
        BRCA1-B complex
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
        BRCA1-C complex
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
        BRCA complex
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
      FA (Fanconi anemia) pathway
        Downstream FA components
          100388186 BRCA1; breast cancer type 1 susceptibility protein isoform X1	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]