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KEGG Orthology (KO) [BR:aml00001]
  09130 Environmental Information Processing
    09132 Signal transduction
      04024 cAMP signaling pathway [PATH:aml04024]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04022 cGMP-PKG signaling pathway [PATH:aml04022]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
  09150 Organismal Systems
    09152 Endocrine system
      04911 Insulin secretion [PATH:aml04911]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04918 Thyroid hormone synthesis [PATH:aml04918]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04919 Thyroid hormone signaling pathway [PATH:aml04919]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04925 Aldosterone synthesis and secretion [PATH:aml04925]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
    09153 Circulatory system
      04260 Cardiac muscle contraction [PATH:aml04260]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04261 Adrenergic signaling in cardiomyocytes [PATH:aml04261]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
    09154 Digestive system
      04970 Salivary secretion [PATH:aml04970]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04971 Gastric acid secretion [PATH:aml04971]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04972 Pancreatic secretion [PATH:aml04972]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04976 Bile secretion [PATH:aml04976]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04973 Carbohydrate digestion and absorption [PATH:aml04973]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04974 Protein digestion and absorption [PATH:aml04974]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04978 Mineral absorption [PATH:aml04978]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
    09155 Excretory system
      04960 Aldosterone-regulated sodium reabsorption [PATH:aml04960]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04961 Endocrine and other factor-regulated calcium reabsorption [PATH:aml04961]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
      04964 Proximal tubule bicarbonate reclamation [PATH:aml04964]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
  09180 Brite Hierarchies
    09183 Protein families: signaling and cellular processes
      04147 Exosome [BR:aml04147]
        100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]

Enzymes [BR:aml01000]
  7. Translocases
    7.2  Catalysing the translocation of inorganic cations
      7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
        7.2.2.13  Na+/K+-exchanging ATPase
          100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13] 

Exosome [BR:aml04147]
  Exosomal proteins
    Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
      100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13] 
    Exosomal proteins of other body fluids (saliva and urine)
      100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13] 
    Exosomal proteins of colorectal cancer cells
      100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13] 
    Exosomal proteins of bladder cancer cells
      100480641 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2	K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13] 

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