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KEGG Orthology (KO) [BR:hsa00001]
  09120 Genetic Information Processing
    09123 Folding, sorting and degradation
      04120 Ubiquitin mediated proteolysis [PATH:hsa04120]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
  09130 Environmental Information Processing
    09132 Signal transduction
      04010 MAPK signaling pathway [PATH:hsa04010]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
  09140 Cellular Processes
    09144 Cellular community - eukaryotes
      04530 Tight junction [PATH:hsa04530]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
  09150 Organismal Systems
    09151 Immune system
      04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
    09152 Endocrine system
      04912 GnRH signaling pathway [PATH:hsa04912]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
      04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
    09156 Nervous system
      04722 Neurotrophin signaling pathway [PATH:hsa04722]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
  09160 Human Diseases
    09172 Infectious disease: viral
      05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
      05161 Hepatitis B [PATH:hsa05161]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
  09180 Brite Hierarchies
    09181 Protein families: metabolism
      01001 Protein kinases [BR:hsa01001]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
    09182 Protein families: genetic information processing
      04121 Ubiquitin system [BR:hsa04121]
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]

Enzymes [BR:hsa01000]
  2. Transferases
    2.7  Transferring phosphorus-containing groups
      2.7.11  Protein-serine/threonine kinases
        2.7.11.25  mitogen-activated protein kinase kinase kinase
          4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] 

Protein kinases [BR:hsa01001]
  Serine/threonine kinases: STE group
    STE11 family
      4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] 

Ubiquitin system [BR:hsa04121]
  Ubiquitin ligases (E3)
    Single Ring-finger type E3
      Other single Ring-finger type E3
        4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1	K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] 

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