Search BRITE hierarchies

KEGG Orthology (KO) [BR:hsa00001]
  09120 Genetic Information Processing
    09123 Folding, sorting and degradation
      04141 Protein processing in endoplasmic reticulum [PATH:hsa04141]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
      04120 Ubiquitin mediated proteolysis [PATH:hsa04120]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
  09140 Cellular Processes
    09141 Transport and catabolism
      04137 Mitophagy - animal [PATH:hsa04137]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
  09160 Human Diseases
    09164 Neurodegenerative disease
      05012 Parkinson disease [PATH:hsa05012]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
      05014 Amyotrophic lateral sclerosis [PATH:hsa05014]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
      05022 Pathways of neurodegeneration - multiple diseases [PATH:hsa05022]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
  09180 Brite Hierarchies
    09182 Protein families: genetic information processing
      04131 Membrane trafficking [BR:hsa04131]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
      04121 Ubiquitin system [BR:hsa04121]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]
      03029 Mitochondrial biogenesis [BR:hsa03029]
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]

Enzymes [BR:hsa01000]
  2. Transferases
    2.3  Acyltransferases
      2.3.2  Aminoacyltransferases
        2.3.2.31  RBR-type E3 ubiquitin transferase
          5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31] 

Membrane trafficking [BR:hsa04131]
  Autophagy
    Mitophagy
      PINK1-Parkin associated proteins
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31] 
    Aggrephagy
      Other aggrephagy associated proteins
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31] 
    Xenophagy
      Other xenophagy associated proteins
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31] 

Ubiquitin system [BR:hsa04121]
  Ubiquitin ligases (E3)
    Single Ring-finger type E3
      RBR proteins
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31] 

Mitochondrial biogenesis [BR:hsa03029]
  Mitochondrial quality control factors
    Mitophagy factors
      Parkin-dependent mechanism factors
        5071 PRKN; parkin RBR E3 ubiquitin protein ligase	K04556 PARK2; parkin [EC:2.3.2.31]