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KEGG Orthology (KO) [BR:hsa00001]
  09120 Genetic Information Processing
    09123 Folding, sorting and degradation
      04141 Protein processing in endoplasmic reticulum [PATH:hsa04141]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
  09130 Environmental Information Processing
    09132 Signal transduction
      04014 Ras signaling pathway [PATH:hsa04014]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04010 MAPK signaling pathway [PATH:hsa04010]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04012 ErbB signaling pathway [PATH:hsa04012]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04310 Wnt signaling pathway [PATH:hsa04310]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04668 TNF signaling pathway [PATH:hsa04668]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04068 FoxO signaling pathway [PATH:hsa04068]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04071 Sphingolipid signaling pathway [PATH:hsa04071]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04024 cAMP signaling pathway [PATH:hsa04024]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
  09140 Cellular Processes
    09141 Transport and catabolism
      04140 Autophagy - animal [PATH:hsa04140]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04137 Mitophagy - animal [PATH:hsa04137]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09143 Cell growth and death
      04210 Apoptosis [PATH:hsa04210]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04215 Apoptosis - multiple species [PATH:hsa04215]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04217 Necroptosis [PATH:hsa04217]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09144 Cellular community - eukaryotes
      04510 Focal adhesion [PATH:hsa04510]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04530 Tight junction [PATH:hsa04530]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
  09150 Organismal Systems
    09151 Immune system
      04620 Toll-like receptor signaling pathway [PATH:hsa04620]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04621 NOD-like receptor signaling pathway [PATH:hsa04621]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04660 T cell receptor signaling pathway [PATH:hsa04660]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04659 Th17 cell differentiation [PATH:hsa04659]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04657 IL-17 signaling pathway [PATH:hsa04657]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09152 Endocrine system
      04910 Insulin signaling pathway [PATH:hsa04910]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04920 Adipocytokine signaling pathway [PATH:hsa04920]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04912 GnRH signaling pathway [PATH:hsa04912]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04917 Prolactin signaling pathway [PATH:hsa04917]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04926 Relaxin signaling pathway [PATH:hsa04926]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09156 Nervous system
      04728 Dopaminergic synapse [PATH:hsa04728]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04723 Retrograde endocannabinoid signaling [PATH:hsa04723]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04722 Neurotrophin signaling pathway [PATH:hsa04722]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09157 Sensory system
      04750 Inflammatory mediator regulation of TRP channels [PATH:hsa04750]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09158 Development and regeneration
      04380 Osteoclast differentiation [PATH:hsa04380]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
  09160 Human Diseases
    09161 Cancer: overview
      05200 Pathways in cancer [PATH:hsa05200]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05231 Choline metabolism in cancer [PATH:hsa05231]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09162 Cancer: specific types
      05210 Colorectal cancer [PATH:hsa05210]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05212 Pancreatic cancer [PATH:hsa05212]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09166 Cardiovascular disease
      05418 Fluid shear stress and atherosclerosis [PATH:hsa05418]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09167 Endocrine and metabolic disease
      04930 Type II diabetes mellitus [PATH:hsa04930]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:hsa04932]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04931 Insulin resistance [PATH:hsa04931]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09171 Infectious disease: bacterial
      05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:hsa05120]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05130 Pathogenic Escherichia coli infection [PATH:hsa05130]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05132 Salmonella infection [PATH:hsa05132]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05131 Shigellosis [PATH:hsa05131]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05135 Yersinia infection [PATH:hsa05135]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05133 Pertussis [PATH:hsa05133]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05152 Tuberculosis [PATH:hsa05152]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09172 Infectious disease: viral
      05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05162 Measles [PATH:hsa05162]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05161 Hepatitis B [PATH:hsa05161]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05169 Epstein-Barr virus infection [PATH:hsa05169]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09174 Infectious disease: parasitic
      05145 Toxoplasmosis [PATH:hsa05145]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
      05142 Chagas disease (American trypanosomiasis) [PATH:hsa05142]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
    09176 Drug resistance: antineoplastic
      01522 Endocrine resistance [PATH:hsa01522]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
  09180 Brite Hierarchies
    09181 Protein families: metabolism
      01001 Protein kinases [BR:hsa01001]
        5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]

Enzymes [BR:hsa01000]
  2. Transferases
    2.7  Transferring phosphorus-containing groups
      2.7.11  Protein-serine/threonine kinases
        2.7.11.24  mitogen-activated protein kinase
          5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] 

Protein kinases [BR:hsa01001]
  Serine/threonine kinases: CMGC group
    MAPK family [OT]
      5599 MAPK8; mitogen-activated protein kinase 8	K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] 

[ BRITE | KEGG2 | KEGG ]