Search BRITE hierarchies

KEGG Orthology (KO) [BR:hsa00001]
  09100 Metabolism
    09105 Amino acid metabolism
      00350 Tyrosine metabolism [PATH:hsa00350]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
    09108 Metabolism of cofactors and vitamins
      00790 Folate biosynthesis [PATH:hsa00790]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
  09150 Organismal Systems
    09152 Endocrine system
      04917 Prolactin signaling pathway [PATH:hsa04917]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
    09156 Nervous system
      04728 Dopaminergic synapse [PATH:hsa04728]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
  09160 Human Diseases
    09164 Neurodegenerative disease
      05012 Parkinson disease [PATH:hsa05012]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
    09165 Substance dependence
      05030 Cocaine addiction [PATH:hsa05030]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
      05031 Amphetamine addiction [PATH:hsa05031]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
      05034 Alcoholism [PATH:hsa05034]
        7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]

Enzymes [BR:hsa01000]
  1. Oxidoreductases
    1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
      1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
        1.14.16.2  tyrosine 3-monooxygenase
          7054 TH; tyrosine hydroxylase	K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]