Search BRITE hierarchies
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway [PATH:hsa04668]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis [PATH:hsa04210]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04215 Apoptosis - multiple species [PATH:hsa04215]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04217 Necroptosis [PATH:hsa04217]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04115 p53 signaling pathway [PATH:hsa04115]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway [PATH:hsa04620]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04621 NOD-like receptor signaling pathway [PATH:hsa04621]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04657 IL-17 signaling pathway [PATH:hsa04657]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer [PATH:hsa05200]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05203 Viral carcinogenesis [PATH:hsa05203]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05161 Hepatitis B [PATH:hsa05161]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05160 Hepatitis C [PATH:hsa05160]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05164 Influenza A [PATH:hsa05164]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05162 Measles [PATH:hsa05162]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05168 Herpes simplex virus 1 infection [PATH:hsa05168]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05163 Human cytomegalovirus infection [PATH:hsa05163]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05169 Epstein-Barr virus infection [PATH:hsa05169]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05165 Human papillomavirus infection [PATH:hsa05165]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection [PATH:hsa05130]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05132 Salmonella infection [PATH:hsa05132]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05134 Legionellosis [PATH:hsa05134]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05152 Tuberculosis [PATH:hsa05152]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09174 Infectious disease: parasitic
05145 Toxoplasmosis [PATH:hsa05145]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05142 Chagas disease [PATH:hsa05142]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09164 Neurodegenerative disease
05010 Alzheimer disease [PATH:hsa05010]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05016 Huntington disease [PATH:hsa05016]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05022 Pathways of neurodegeneration - multiple diseases [PATH:hsa05022]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09166 Cardiovascular disease
05417 Lipid and atherosclerosis [PATH:hsa05417]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
05416 Viral myocarditis [PATH:hsa05416]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease [PATH:hsa04936]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
04932 Non-alcoholic fatty liver disease [PATH:hsa04932]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance [PATH:hsa01524]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:hsa01002]
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
Enzymes [BR:hsa01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.61 caspase-8
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
Peptidases and inhibitors [BR:hsa01002]
Cysteine peptidases
Family C14: caspase family
841 CASP8; caspase 8 K04398 CASP8; caspase 8 [EC:3.4.22.61]
[ BRITE | KEGG2 | KEGG ]