Search BRITE hierarchies

KEGG Orthology (KO) [BR:ko00001]
  09100 Metabolism
    09104 Nucleotide metabolism
      00230 Purine metabolism [PATH:ko00230]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
  09130 Environmental Information Processing
    09132 Signal transduction
      04015 Rap1 signaling pathway [PATH:ko04015]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04371 Apelin signaling pathway [PATH:ko04371]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04020 Calcium signaling pathway [PATH:ko04020]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04072 Phospholipase D signaling pathway [PATH:ko04072]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04024 cAMP signaling pathway [PATH:ko04024]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04022 cGMP-PKG signaling pathway [PATH:ko04022]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
  09140 Cellular Processes
    09143 Cell growth and death
      04114 Oocyte meiosis [PATH:ko04114]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09144 Cellular community - eukaryotes
      04540 Gap junction [PATH:ko04540]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
  09150 Organismal Systems
    09151 Immune system
      04611 Platelet activation [PATH:ko04611]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04062 Chemokine signaling pathway [PATH:ko04062]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09152 Endocrine system
      04911 Insulin secretion [PATH:ko04911]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04923 Regulation of lipolysis in adipocytes [PATH:ko04923]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04912 GnRH signaling pathway [PATH:ko04912]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04913 Ovarian steroidogenesis [PATH:ko04913]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04915 Estrogen signaling pathway [PATH:ko04915]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04921 Oxytocin signaling pathway [PATH:ko04921]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04926 Relaxin signaling pathway [PATH:ko04926]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04935 Growth hormone synthesis, secretion and action [PATH:ko04935]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04918 Thyroid hormone synthesis [PATH:ko04918]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04928 Parathyroid hormone synthesis, secretion and action [PATH:ko04928]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04916 Melanogenesis [PATH:ko04916]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04925 Aldosterone synthesis and secretion [PATH:ko04925]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04927 Cortisol synthesis and secretion [PATH:ko04927]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09153 Circulatory system
      04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04270 Vascular smooth muscle contraction [PATH:ko04270]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09154 Digestive system
      04970 Salivary secretion [PATH:ko04970]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04971 Gastric acid secretion [PATH:ko04971]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04972 Pancreatic secretion [PATH:ko04972]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04976 Bile secretion [PATH:ko04976]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09156 Nervous system
      04724 Glutamatergic synapse [PATH:ko04724]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04727 GABAergic synapse [PATH:ko04727]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04725 Cholinergic synapse [PATH:ko04725]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04723 Retrograde endocannabinoid signaling [PATH:ko04723]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09157 Sensory system
      04742 Taste transduction [PATH:ko04742]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04750 Inflammatory mediator regulation of TRP channels [PATH:ko04750]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09149 Aging
      04211 Longevity regulating pathway [PATH:ko04211]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04213 Longevity regulating pathway - multiple species [PATH:ko04213]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09159 Environmental adaptation
      04713 Circadian entrainment [PATH:ko04713]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      04714 Thermogenesis [PATH:ko04714]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
  09160 Human Diseases
    09161 Cancer: overview
      05200 Pathways in cancer [PATH:ko05200]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09165 Substance dependence
      05032 Morphine addiction [PATH:ko05032]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09166 Cardiovascular disease
      05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09167 Endocrine and metabolic disease
      04934 Cushing syndrome [PATH:ko04934]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09172 Infectious disease: viral
      05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
      05163 Human cytomegalovirus infection [PATH:ko05163]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
    09176 Drug resistance: antineoplastic
      01522 Endocrine resistance [PATH:ko01522]
        K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]

Enzymes [BR:ko01000]
  4. Lyases
    4.6  Phosphorus-oxygen lyases
      4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
        4.6.1.1  adenylate cyclase
          K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]

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