KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:awd00010 awd01200 awd01230 awd01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:awd00010 awd00020 awd01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:awd00010 awd00020 awd00620 awd01200 awd01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:awd00020 awd01200 awd01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:awd00020 awd01200 awd01210 awd01230 awd01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:awd00020 awd01200 awd01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:awd00030 awd01200 awd01100 awd01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:awd00030 awd01200 awd01100 awd01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:awd00030 awd01200 awd01230 awd01100 awd01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:awd00030 awd00230 awd01200 awd01230 awd01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:awd00052 awd01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:awd00500 awd01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:awd00500 awd01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:awd00520 awd00052 awd01100]
M00012 Glyoxylate cycle [PATH:awd00630 awd01200 awd01100 awd01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:awd00620 awd01200 awd01100 awd01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:awd00430 awd00620 awd01200 awd01100 awd01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:awd00910 awd01100 awd01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:awd00920 awd01100 awd01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:awd00190]
M00150 Fumarate reductase, prokaryotes [PATH:awd00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:awd00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:awd00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:awd00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:awd00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:awd00061 awd01212 awd01100]
M00083 Fatty acid biosynthesis, elongation [PATH:awd00061 awd01212 awd01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:awd00061 awd00071 awd01212 awd01100]
M00087 beta-Oxidation [PATH:awd00071 awd01212 awd01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:awd00564 awd01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:awd00230 awd01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:awd00230 awd01240 awd01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:awd00230 awd01100]

Pyrimidine metabolism
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH:awd00240 awd01240 awd01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:awd00240 awd01240 awd01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:awd00260 awd00680 awd01200 awd01230 awd01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:awd00260 awd01230 awd01100 awd01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:awd00260 awd01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:awd00260 awd01210 awd01230 awd01100 awd01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:awd00270 awd00920 awd01200 awd01230 awd01100 awd01110]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:awd00270 awd01230 awd01100]

Branched-chain amino acid metabolism
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:awd00290 awd01210 awd01230 awd01100 awd01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:awd00300 awd01230 awd01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:awd00220 awd01210 awd01230 awd01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:awd00220 awd01230 awd01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:awd00330 awd01230 awd01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:awd00340 awd01230 awd01100 awd01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:awd00340 awd01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:awd00400 awd01230 awd01100 awd01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:awd00400 awd01230 awd01100 awd01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:awd00400 awd01230 awd01100 awd01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:awd00400 awd01230 awd01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:awd00480 awd01240 awd01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:awd00540 awd01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:awd00540 awd01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:awd00730 awd01240 awd01100]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:awd00750 awd01240 awd01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:awd00760 awd01240 awd01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:awd00770 awd01240 awd01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:awd00780 awd01240 awd01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:awd00785 awd01240 awd01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:awd00790 awd00670 awd01240 awd01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:awd00790 awd01240 awd01100]
M00140 C1-unit interconversion, prokaryotes [PATH:awd00670 awd01240 awd01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:awd00860 awd01240 awd01100 awd01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:awd00860 awd01240 awd01100 awd01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:awd00130 awd01240 awd01100 awd01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:awd00130 awd01240 awd01100 awd01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:awd00900 awd01100 awd01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:awd00900 awd01100 awd01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:awd00521 awd00523 awd00541 awd01100 awd01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity