KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:clv00010 clv01200 clv01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:clv00010 clv01200 clv01230 clv01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:clv00010 clv00020 clv01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:clv00010 clv00020 clv00620 clv00785 clv01200 clv01210 clv01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:clv00020 clv01200 clv01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:clv00020 clv01200 clv01210 clv01230 clv01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:clv00020 clv01200 clv01210 clv01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:clv00030 clv01200 clv01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:clv00030 clv01200 clv01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:clv00030 clv01200 clv01230 clv01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:clv00030 clv00230 clv01200 clv01230 clv01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:clv00040 clv01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:clv00052 clv01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:clv00040 clv00053 clv01240 clv01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:clv00500 clv01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:clv00500 clv01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:clv00562 clv01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:clv00562 clv01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:clv00562 clv01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00142 NADH:ubiquinone oxidoreductase, mitochondria [PATH:clv00190 clv01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:clv00190 clv01100]
M00160 V-type ATPase, eukaryotes [PATH:clv00190 clv01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:clv00061 clv01212 clv01100]
M00083 Fatty acid biosynthesis, elongation [PATH:clv00061 clv01212 clv01100]
M00085 Fatty acid elongation in mitochondria [PATH:clv00062 clv01212 clv01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:clv00062 clv01040 clv01212 clv01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:clv00061 clv00071 clv01212 clv01100]
M00087 beta-Oxidation [PATH:clv00071 clv01212 clv01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:clv01040 clv01212 clv01100]

Sterol biosynthesis
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH:clv00120 clv01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:clv00140 clv01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:clv00140 clv01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:clv00140 clv01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:clv00561 clv01100]
M00098 Acylglycerol degradation [PATH:clv00561 clv01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:clv00564 clv01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:clv00564 clv01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:clv00564 clv01100]
M00094 Ceramide biosynthesis [PATH:clv00600 clv01100]
M00066 Lactosylceramide biosynthesis [PATH:clv00600 clv01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:clv00600 clv00565 clv01100]
M00099 Sphingosine biosynthesis [PATH:clv00600 clv01100]
M00100 Sphingosine degradation [PATH:clv00600 clv01100]

Nucleotide metabolism
Purine metabolism
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:clv00230 clv01232 clv01240 clv01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:clv00230 clv01232 clv01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:clv00230 clv00240 clv01232 clv01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:clv00230 clv01232 clv01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:clv00230 clv01232 clv01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:clv00240 clv01240 clv01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:clv00240 clv01232 clv01240 clv01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:clv00240 clv01232 clv01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:clv00240 clv00410 clv00770 clv01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:clv00260 clv01200 clv01230 clv01100]
M00621 Glycine cleavage system [PATH:clv00260 clv00630 clv00670 clv00785 clv01200 clv01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:clv00260 clv00670 clv01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:clv00260 clv00670 clv01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:clv00260 clv00270 clv00670 clv01230 clv01100]
M00035 Methionine degradation [PATH:clv00270 clv00670 clv01100]

Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:clv00220 clv01230 clv01100]
M00029 Urea cycle [PATH:clv00220 clv01230 clv01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:clv00330 clv01230 clv01100]
M00970 Proline degradation, proline => glutamate [PATH:clv00330 clv01100]
M00972 Proline metabolism [PATH:clv00330 clv01100]
M00047 Creatine pathway [PATH:clv00330 clv00260 clv01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:clv00330 clv01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:clv00330 clv01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:clv00340 clv01100]

Aromatic amino acid metabolism
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:clv00350 clv01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:clv00350 clv01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:clv00380 clv01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:clv00380 clv01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:clv00250 clv00650 clv01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:clv00480 clv01240 clv01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:clv00520 clv01250 clv01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:clv00520 clv00052 clv01250 clv01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:clv00520 clv01250 clv01100]

Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:clv00510 clv01100]
M00075 N-glycan biosynthesis, complex type [PATH:clv00510 clv01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:clv00563 clv01100]
M00983 GPI-anchor remodeling [PATH:clv00563 clv01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:clv00601 clv01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:clv00601 clv01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:clv00603 clv01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:clv00604 clv01100]

Glycosaminoglycan metabolism
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:clv00532 clv01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:clv00534 clv01100]
M00076 Dermatan sulfate degradation [PATH:clv00531 clv01100]
M00077 Chondroitin sulfate degradation [PATH:clv00531 clv01100]
M00078 Heparan sulfate degradation [PATH:clv00531 clv01100]
M00079 Keratan sulfate degradation [PATH:clv00531 clv01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:clv00785 clv01240 clv01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:clv00785 clv01240 clv01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:clv00790 clv01240 clv01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:clv00790 clv01240 clv01100]
M00141 C1-unit interconversion, eukaryotes [PATH:clv00670 clv01240 clv01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:clv00860 clv01240 clv01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:clv00900 clv01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:clv00900 clv01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity