KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:eic00010 eic01200 eic01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:eic00010 eic01200 eic01230 eic01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:eic00010 eic00020 eic01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:eic00010 eic00020 eic00620 eic01200 eic01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:eic00020 eic01200 eic01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:eic00020 eic01200 eic01210 eic01230 eic01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:eic00020 eic01200 eic01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:eic00030 eic01200 eic01100 eic01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:eic00030 eic01200 eic01100 eic01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:eic00030 eic01200 eic01230 eic01100 eic01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:eic00030 eic00230 eic01200 eic01230 eic01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:eic00030 eic01200 eic01100 eic01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:eic00040 eic00030 eic01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:eic00040 eic00030 eic01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:eic00052 eic01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:eic00053 eic01100 eic01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:eic00500 eic01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:eic00500 eic01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:eic00520 eic01250 eic01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:eic00520 eic00052 eic01250 eic01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:eic00520 eic01250 eic01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:eic00520 eic01100]
M00012 Glyoxylate cycle [PATH:eic00630 eic01200 eic01100 eic01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:eic00620 eic01200 eic01100 eic01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:eic00430 eic00620 eic01200 eic01100 eic01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:eic00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH:eic00190]
M00150 Fumarate reductase, prokaryotes [PATH:eic00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:eic00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:eic00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:eic00061 eic01212 eic01100]
M00083 Fatty acid biosynthesis, elongation [PATH:eic00061 eic01212 eic01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:eic00061 eic00071 eic01212 eic01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:eic00564 eic01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:eic00230 eic01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:eic00230 eic01232 eic01240 eic01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:eic00230 eic01232 eic01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:eic00230 eic00240 eic01232 eic01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:eic00230 eic01232 eic01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:eic00230 eic01232 eic01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:eic00240 eic01240 eic01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:eic00240 eic01232 eic01240 eic01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:eic00240 eic01232 eic01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:eic00260 eic00680 eic01200 eic01230 eic01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:eic00260 eic01230 eic01100 eic01110]
M00621 Glycine cleavage system [PATH:eic00260 eic00630 eic01200 eic01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:eic00270 eic00920 eic01200 eic01230 eic01100 eic01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:eic00270 eic01230 eic01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:eic00290 eic00770 eic01210 eic01230 eic01100 eic01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:eic00290 eic01230 eic01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:eic00290 eic01210 eic01230 eic01100 eic01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:eic00300 eic01230 eic01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:eic00220 eic01210 eic01230 eic01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:eic00220 eic01230 eic01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:eic00330 eic01230 eic01100]
M00970 Proline degradation, proline => glutamate [PATH:eic00330 eic01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:eic00340 eic01230 eic01100 eic01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:eic00400 eic01230 eic01100 eic01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:eic00400 eic01230 eic01100 eic01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:eic00400 eic01230 eic01100 eic01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:eic00400 eic01230 eic01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:eic00480 eic01240 eic01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:eic00540 eic01250 eic01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:eic00540 eic01250 eic01100]
M00922 CMP-Neu5Ac biosynthesis [PATH:eic00541 eic01250 eic01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:eic00730 eic01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:eic00740 eic01240 eic01100 eic01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:eic00750 eic01240 eic01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:eic00770 eic01240 eic01100 eic01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:eic00770 eic01240 eic01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:eic00780 eic01240 eic01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:eic00785 eic01240 eic01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:eic00790 eic00670 eic01240 eic01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:eic00790 eic01240 eic01100]
M00140 C1-unit interconversion, prokaryotes [PATH:eic00670 eic01240 eic01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:eic00860 eic01240 eic01100 eic01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:eic00860 eic01240 eic01100 eic01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:eic00860 eic01240 eic01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:eic00860 eic01240 eic01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:eic00130 eic01240 eic01100 eic01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:eic00130 eic01240 eic01100 eic01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:eic00900 eic01100 eic01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:eic00900 eic01100 eic01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity