KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:enf00010 enf01200 enf01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:enf00010 enf01200 enf01230 enf01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:enf00010 enf00020 enf01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:enf00010 enf00020 enf00620 enf01200 enf01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:enf00020 enf01200 enf01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:enf00020 enf01200 enf01210 enf01230 enf01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:enf00020 enf01200 enf01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:enf00030 enf01200 enf01100 enf01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:enf00030 enf01200 enf01100 enf01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:enf00030 enf01200 enf01230 enf01100 enf01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:enf00030 enf00230 enf01200 enf01230 enf01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:enf00030 enf01200 enf01100 enf01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:enf00040 enf00030 enf01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:enf00040 enf00030 enf01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:enf00052 enf01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:enf00500 enf01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:enf00500 enf01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:enf00500 enf01100 enf01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:enf00520 enf01250 enf01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:enf00520 enf00052 enf01250 enf01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:enf00520 enf01250 enf01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:enf00520 enf01100]
M00012 Glyoxylate cycle [PATH:enf00630 enf01200 enf01100 enf01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:enf00620 enf01200 enf01100 enf01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:enf00430 enf00620 enf01200 enf01100 enf01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:enf00910 enf01100 enf01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:enf00910 enf01100 enf01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:enf00920 enf01100 enf01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:enf00190]
M00150 Fumarate reductase, prokaryotes [PATH:enf00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:enf00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:enf00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:enf00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:enf00061 enf01212 enf01100]
M00083 Fatty acid biosynthesis, elongation [PATH:enf00061 enf01212 enf01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:enf00061 enf00071 enf01212 enf01100]
M00087 beta-Oxidation [PATH:enf00071 enf01212 enf01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:enf00564 enf01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:enf00230 enf01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:enf00230 enf01232 enf01240 enf01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:enf00230 enf01232 enf01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:enf00230 enf00240 enf01232 enf01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:enf00240 enf01240 enf01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:enf00240 enf01232 enf01240 enf01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:enf00240 enf01232 enf01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:enf00240 enf00410 enf00770 enf01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:enf00240 enf01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:enf00260 enf00680 enf01200 enf01230 enf01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:enf00260 enf01230 enf01100 enf01110]
M00621 Glycine cleavage system [PATH:enf00260 enf00630 enf01200 enf01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:enf00270 enf00920 enf01200 enf01230 enf01100 enf01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:enf00260 enf00270 enf01230 enf01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:enf00270 enf01230 enf01100]
M00034 Methionine salvage pathway [PATH:enf00270 enf01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:enf00290 enf00770 enf01210 enf01230 enf01100 enf01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:enf00290 enf01230 enf01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:enf00290 enf01210 enf01230 enf01100 enf01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:enf00300 enf01230 enf01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:enf00220 enf01210 enf01230 enf01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:enf00220 enf01230 enf01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:enf00330 enf01230 enf01100]
M00970 Proline degradation, proline => glutamate [PATH:enf00330 enf01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:enf00330 enf01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:enf00340 enf01230 enf01100 enf01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:enf00340 enf01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:enf00400 enf01230 enf01100 enf01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:enf00400 enf01230 enf01100 enf01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:enf00400 enf01230 enf01100 enf01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:enf00400 enf01230 enf01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:enf00480 enf01240 enf01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:enf00540 enf01100]
M00063 CMP-KDO biosynthesis [PATH:enf00540 enf01250 enf01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:enf00540 enf01250 enf01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:enf00730 enf01240 enf01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:enf00730 enf01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:enf00740 enf01240 enf01100 enf01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:enf00750 enf01240 enf01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:enf00760 enf01240 enf01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:enf00770 enf01240 enf01100 enf01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:enf00770 enf01240 enf01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:enf00780 enf01240 enf01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:enf00780 enf01240 enf01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:enf00785 enf01240 enf01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:enf00790 enf00670 enf01240 enf01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:enf00790 enf01240 enf01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:enf00860 enf01240 enf01100 enf01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:enf00860 enf01240 enf01100 enf01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:enf00860 enf01240 enf01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:enf00860 enf01240 enf01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:enf00130 enf01240 enf01100 enf01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:enf00130 enf01240 enf01100 enf01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:enf00900 enf01100 enf01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:enf00900 enf01100 enf01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:enf00521 enf00523 enf00541 enf01250 enf01100 enf01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation