KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:etd00010 etd01200 etd01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:etd00010 etd01200 etd01230 etd01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:etd00010 etd00020 etd01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:etd00010 etd00020 etd00620 etd00785 etd01200 etd01210 etd01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:etd00020 etd01200 etd01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:etd00020 etd01200 etd01210 etd01230 etd01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:etd00020 etd01200 etd01210 etd01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:etd00030 etd01200 etd01100 etd01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:etd00030 etd01200 etd01100 etd01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:etd00030 etd01200 etd01230 etd01100 etd01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:etd00030 etd00230 etd01200 etd01230 etd01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:etd00030 etd01200 etd01100 etd01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:etd00040 etd00030 etd01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:etd00040 etd00030 etd01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:etd00052 etd01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:etd00053 etd01100 etd01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:etd00500 etd01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:etd00500 etd01100]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:etd00620 etd00710 etd01200 etd01100 etd01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:etd00430 etd00620 etd00720 etd01200 etd01100 etd01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:etd00190 etd01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:etd00190 etd01100]
M00150 Fumarate reductase, prokaryotes [PATH:etd00190 etd01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:etd00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:etd00190 etd01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:etd00061 etd01212 etd01100]
M00083 Fatty acid biosynthesis, elongation [PATH:etd00061 etd01212 etd01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:etd00061 etd00071 etd01212 etd01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:etd00564 etd01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:etd00230 etd01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:etd00230 etd01232 etd01240 etd01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:etd00230 etd01232 etd01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:etd00230 etd00240 etd01232 etd01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:etd00230 etd01232 etd01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:etd00230 etd01232 etd01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:etd00240 etd01240 etd01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:etd00240 etd01232 etd01240 etd01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:etd00240 etd01232 etd01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:etd00260 etd00680 etd01200 etd01230 etd01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:etd00260 etd01230 etd01100 etd01110]
M00621 Glycine cleavage system [PATH:etd00260 etd00630 etd00670 etd00785 etd01200 etd01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:etd00270 etd00920 etd01200 etd01230 etd01100 etd01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:etd00260 etd00270 etd00670 etd01230 etd01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:etd00270 etd01230 etd01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:etd00290 etd00770 etd01210 etd01230 etd01100 etd01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:etd00290 etd01230 etd01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:etd00290 etd01210 etd01230 etd01100 etd01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:etd00300 etd01230 etd01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:etd00220 etd01210 etd01230 etd01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:etd00220 etd01230 etd01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:etd00330 etd01230 etd01100]
M00970 Proline degradation, proline => glutamate [PATH:etd00330 etd01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:etd00340 etd01230 etd01100 etd01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:etd00400 etd01230 etd01100 etd01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:etd00400 etd01230 etd01100 etd01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:etd00400 etd01230 etd01100 etd01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:etd00400 etd01230 etd01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:etd00480 etd01240 etd01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:etd00520 etd01250 etd01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:etd00520 etd00052 etd01250 etd01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:etd00520 etd01250 etd01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:etd00541 etd01250 etd01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:etd00541 etd01250 etd01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:etd00541 etd01100]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:etd00540 etd01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:etd00730 etd01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:etd00740 etd01240 etd01100 etd01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:etd00750 etd01240 etd01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:etd00770 etd01240 etd01100 etd01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:etd00770 etd01240 etd01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:etd00780 etd01240 etd01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:etd00785 etd01240 etd01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:etd00790 etd00670 etd01240 etd01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:etd00790 etd01240 etd01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:etd00790 etd01100]
M00140 C1-unit interconversion, prokaryotes [PATH:etd00670 etd01240 etd01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:etd00860 etd01240 etd01100 etd01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:etd00860 etd01240 etd01100 etd01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:etd00860 etd01240 etd01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:etd00860 etd01240 etd01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:etd00130 etd01240 etd01100 etd01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:etd00130 etd01240]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:etd00130 etd01240 etd01100 etd01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:etd00900 etd01100 etd01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:etd00900 etd01100 etd01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity