KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:hir00010 hir01200 hir01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:hir00010 hir01200 hir01230 hir01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:hir00010 hir00020 hir01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:hir00010 hir00020 hir00620 hir00785 hir01200 hir01210 hir01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:hir00020 hir01200 hir01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:hir00020 hir01200 hir01210 hir01230 hir01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:hir00020 hir01200 hir01210 hir01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:hir00030 hir01200 hir01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:hir00030 hir01200 hir01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:hir00030 hir01200 hir01230 hir01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:hir00030 hir00230 hir01200 hir01230 hir01100]

Other carbohydrate metabolism
M00081 Pectin degradation [PATH:hir00040 hir01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:hir00500 hir01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:hir00500 hir01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:hir00520 hir01250 hir01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:hir00520 hir01250 hir01100]
M00012 Glyoxylate cycle [PATH:hir00630 hir01200 hir01100 hir01110]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:hir00910 hir01100]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:hir00920 hir01100]

Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:hir00190 hir01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:hir00190 hir01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:hir00061 hir01212 hir01100]
M00083 Fatty acid biosynthesis, elongation [PATH:hir00061 hir01212 hir01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:hir00061 hir00071 hir01212 hir01100]

Sterol biosynthesis
M00102 Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol [PATH:hir00100 hir01100 hir01110]

Lipid metabolism
M00098 Acylglycerol degradation [PATH:hir00561 hir01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:hir00564 hir01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:hir00564 hir01100]
M00094 Ceramide biosynthesis [PATH:hir00600 hir01100]
M00099 Sphingosine biosynthesis [PATH:hir00600 hir01100]
M00100 Sphingosine degradation [PATH:hir00600 hir01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hir00230 hir01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hir00230 hir01232 hir01240 hir01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hir00230 hir01232 hir01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hir00230 hir00240 hir01232 hir01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:hir00230 hir01232 hir01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:hir00230 hir01232 hir01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:hir00240 hir01232 hir01240 hir01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:hir00240 hir01232 hir01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:hir00260 hir01230 hir01100 hir01110]
M00621 Glycine cleavage system [PATH:hir00260 hir00630 hir00785 hir01200 hir01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:hir00260 hir00270 hir01230 hir01100]
M00035 Methionine degradation [PATH:hir00270 hir01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:hir00290 hir00770 hir01210 hir01230 hir01100 hir01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:hir00290 hir01230 hir01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:hir00290 hir01210 hir01230 hir01100 hir01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:hir00280 hir01100]

Lysine metabolism
Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:hir00220 hir01230 hir01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:hir00330 hir01230 hir01100]
M00970 Proline degradation, proline => glutamate [PATH:hir00330 hir01100]
M00972 Proline metabolism [PATH:hir00330 hir01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:hir00330 hir01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:hir00340 hir01230 hir01100 hir01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:hir00400 hir01230 hir01100 hir01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:hir00400 hir01230 hir01100 hir01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:hir00400 hir01230 hir01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:hir00250 hir00650 hir01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:hir00510 hir01100]
M00072 N-glycosylation by oligosaccharyltransferase [PATH:hir00510 hir00513 hir01100]
M00073 N-glycan precursor trimming [PATH:hir00510 hir01100]

Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:hir00750 hir01240 hir01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:hir00780 hir01240 hir01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:hir00785 hir01240 hir01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:hir00790 hir00670 hir01240 hir01100]
M00141 C1-unit interconversion, eukaryotes [PATH:hir00670 hir01240 hir01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:hir00860 hir01240 hir01100 hir01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:hir00130 hir01240 hir01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:hir00900 hir01100 hir01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation