KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:maj00010 maj01200 maj01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:maj00010 maj01200 maj01230 maj01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:maj00010 maj00020 maj01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:maj00010 maj00020 maj00620 maj00785 maj01200 maj01210 maj01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:maj00020 maj01200 maj01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:maj00020 maj01200 maj01210 maj01230 maj01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:maj00020 maj01200 maj01210 maj01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:maj00030 maj01200 maj01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:maj00030 maj01200 maj01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:maj00030 maj01200 maj01230 maj01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:maj00030 maj00230 maj01200 maj01230 maj01100]

Other carbohydrate metabolism
M00630 D-Galacturonate degradation (fungi), D-galacturonate => glycerol [PATH:maj00040 maj01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:maj00052 maj01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:maj00500 maj01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:maj00500 maj01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:maj00520 maj01250 maj01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:maj00520 maj00052 maj01250 maj01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:maj00520 maj01250 maj01100]
M00012 Glyoxylate cycle [PATH:maj00630 maj01200 maj01100 maj01110]
M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH:maj00410 maj00640 maj01200 maj01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:maj00910 maj01100]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:maj00920 maj01100]

Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:maj00190 maj01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:maj00190 maj01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:maj00061 maj01212 maj01100]
M00083 Fatty acid biosynthesis, elongation [PATH:maj00061 maj01212 maj01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:maj00062 maj01040 maj01212 maj01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:maj00061 maj00071 maj01212 maj01100]
M00087 beta-Oxidation [PATH:maj00071 maj01212 maj01100]

Sterol biosynthesis
M00102 Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol [PATH:maj00100 maj01100 maj01110]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:maj00561 maj01100]
M00098 Acylglycerol degradation [PATH:maj00561 maj01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:maj00564 maj01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:maj00564 maj01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:maj00564 maj01100]
M00094 Ceramide biosynthesis [PATH:maj00600 maj01100]
M00099 Sphingosine biosynthesis [PATH:maj00600 maj01100]
M00100 Sphingosine degradation [PATH:maj00600 maj01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:maj00230 maj01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:maj00230 maj01232 maj01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:maj00230 maj00240 maj01232 maj01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:maj00240 maj01240 maj01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:maj00240 maj01232 maj01240 maj01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:maj00240 maj01232 maj01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:maj00260 maj00680 maj01200 maj01230 maj01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:maj00260 maj01230 maj01100 maj01110]
M00621 Glycine cleavage system [PATH:maj00260 maj00630 maj00785 maj01200 maj01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:maj00260 maj00270 maj01230 maj01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:maj00270 maj01230 maj01100]
M00034 Methionine salvage pathway [PATH:maj00270 maj01100]
M00035 Methionine degradation [PATH:maj00270 maj01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:maj00290 maj00770 maj01210 maj01230 maj01100 maj01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:maj00290 maj01230 maj01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:maj00290 maj01210 maj01230 maj01100 maj01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:maj00280 maj01100]

Lysine metabolism
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:maj00300 maj01230 maj01100]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:maj00300 maj01210 maj01230 maj01100]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:maj00220 maj01230 maj01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:maj00330 maj01230 maj01100]
M00970 Proline degradation, proline => glutamate [PATH:maj00330 maj01100]
M00972 Proline metabolism [PATH:maj00330 maj01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:maj00330 maj01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:maj00340 maj01230 maj01100 maj01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:maj00400 maj01230 maj01100 maj01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:maj00400 maj01230 maj01100 maj01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:maj00400 maj01230 maj01100 maj01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:maj00400 maj01230 maj01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:maj00350 maj01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:maj00250 maj00650 maj01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:maj00480 maj01240 maj01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:maj00510 maj01100]
M00072 N-glycosylation by oligosaccharyltransferase [PATH:maj00510 maj00513 maj01100]
M00073 N-glycan precursor trimming [PATH:maj00510 maj01100]

Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00898 Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP [PATH:maj00730 maj01240 maj01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:maj00750 maj01240 maj01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:maj00780 maj01240 maj01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:maj00785 maj01240 maj01100]
M00141 C1-unit interconversion, eukaryotes [PATH:maj00670 maj01240 maj01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:maj00860 maj01240 maj01100 maj01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:maj00130 maj01240 maj01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:maj00900 maj01100 maj01110]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:maj00900 maj01100 maj01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
M00963 Chanoclavine aldehyde biosynthesis, tryptophan => chanoclavine-I aldehyde [PATH:maj00901 maj01100 maj01110]

Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
M00661 Paspaline biosynthesis, geranylgeranyl-PP + indoleglycerol phosphate => paspaline [PATH:maj00403 maj01100 maj01110]

Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation