KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:mei00010 mei01200 mei01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:mei00010 mei01200 mei01230 mei01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:mei00010 mei00020 mei00620 mei00785 mei01200 mei01210 mei01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:mei00020 mei01200 mei01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:mei00020 mei01200 mei01210 mei01230 mei01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:mei00020 mei01200 mei01210 mei01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:mei00030 mei01200 mei01100 mei01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:mei00030 mei01200 mei01100 mei01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:mei00030 mei01200 mei01230 mei01100 mei01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH:mei00030 mei01200 mei01230 mei01100 mei01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:mei00030 mei00230 mei01200 mei01230 mei01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:mei00030 mei01200 mei01100 mei01120]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:mei00500 mei01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:mei00500 mei01100 mei01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:mei00520 mei01250 mei01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:mei00520 mei01250 mei01100]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:mei00620 mei00720 mei01200 mei01100 mei01120]
M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate [PATH:mei00720 mei01200 mei01100 mei01120]

Methane metabolism
M00567 Methanogenesis, CO2 => methane [PATH:mei00680 mei01200 mei01100 mei01120]
M00356 Methanogenesis, methanol => methane [PATH:mei00680 mei01200 mei01100 mei01120]
M00358 Coenzyme M biosynthesis [PATH:mei00680 mei01240 mei01100 mei01120]
M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate [PATH:mei00300 mei00680 mei01210 mei01230 mei01240 mei01100 mei01120]
M00174 Methane oxidation, methanotroph, methane => formaldehyde [PATH:mei00680 mei01200 mei01220 mei01100 mei01120]
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:mei00030 mei00680 mei01200 mei01230 mei01100 mei01120]
M00378 F420 biosynthesis, archaea [PATH:mei00680 mei01240 mei01100 mei01120]

Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:mei00910 mei01100 mei01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:mei00910 mei01100 mei01120]
M00528 Nitrification, ammonia => nitrite [PATH:mei00910 mei01100 mei01120]
M00804 Complete nitrification, comammox, ammonia => nitrite => nitrate [PATH:mei00910 mei01100 mei01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:mei00920 mei01100 mei01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:mei00190 mei01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:mei00190 mei01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:mei00190 mei01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:mei00190 mei01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:mei00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:mei00190 mei01100]
M00159 V/A-type ATPase, prokaryotes [PATH:mei00190 mei01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:mei00061 mei01212 mei01100]
M00083 Fatty acid biosynthesis, elongation [PATH:mei00061 mei01212 mei01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:mei00061 mei00071 mei01212 mei01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:mei00564 mei01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mei00230 mei01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mei00230 mei01232 mei01240 mei01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mei00230 mei01232 mei01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mei00230 mei00240 mei01232 mei01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:mei00240 mei01240 mei01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:mei00240 mei01232 mei01240 mei01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:mei00240 mei01232 mei01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:mei00260 mei00680 mei01200 mei01230 mei01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:mei00260 mei01230 mei01100 mei01110]
M00621 Glycine cleavage system [PATH:mei00260 mei00630 mei00785 mei01200 mei01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:mei00270 mei00920 mei01200 mei01230 mei01100 mei01110]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:mei00290 mei00770 mei01210 mei01230 mei01100 mei01110]
M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH:mei00290 mei00660 mei01210 mei01230 mei01100]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:mei00290 mei01230 mei01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:mei00290 mei01210 mei01230 mei01100 mei01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:mei00300 mei01230 mei01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:mei00300 mei01230 mei01100 mei01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:mei00220 mei01210 mei01230 mei01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:mei00220 mei01230 mei01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:mei00330 mei01230 mei01100]

Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:mei00400 mei01230 mei01100 mei01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:mei00400 mei01230 mei01100 mei01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:mei00480 mei01240 mei01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:mei00540 mei01250 mei01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:mei00540 mei01250 mei01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:mei00730 mei01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:mei00760 mei01240 mei01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:mei00770 mei01240 mei01100 mei01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:mei00770 mei01240 mei01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:mei00780 mei01240 mei01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:mei00780 mei01240 mei01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:mei00785 mei01240 mei01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:mei00790 mei00670 mei01240 mei01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:mei00790 mei01240 mei01100]
M00140 C1-unit interconversion, prokaryotes [PATH:mei00670 mei01240 mei01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:mei00860 mei01240 mei01100 mei01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:mei00860 mei01240 mei01100 mei01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:mei00860 mei01240 mei01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:mei00860 mei01240 mei01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:mei00130 mei01240 mei01100 mei01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00849 C5 isoprenoid biosynthesis, mevalonate pathway, archaea [PATH:mei00900 mei01100 mei01110]
M00365 C10-C20 isoprenoid biosynthesis, archaea [PATH:mei00900 mei01100 mei01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:mei00521 mei00523 mei00541 mei01250 mei01100 mei01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00643 Multidrug resistance, efflux pump MexXY-OprM
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00617 Methanogen
M00615 Nitrate assimilation