KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:mpl00010 mpl01200 mpl01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:mpl00010 mpl01200 mpl01230 mpl01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:mpl00010 mpl00020 mpl01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:mpl00010 mpl00020 mpl00620 mpl00785 mpl01200 mpl01210 mpl01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:mpl00020 mpl01200 mpl01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:mpl00020 mpl01200 mpl01210 mpl01230 mpl01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:mpl00020 mpl01200 mpl01210 mpl01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:mpl00030 mpl01200 mpl01100 mpl01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:mpl00030 mpl01200 mpl01100 mpl01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:mpl00030 mpl01200 mpl01230 mpl01100 mpl01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH:mpl00030 mpl01200 mpl01230 mpl01100 mpl01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:mpl00030 mpl00230 mpl01200 mpl01230 mpl01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:mpl00052 mpl01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:mpl00052 mpl01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:mpl00500 mpl01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:mpl00520 mpl01250 mpl01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:mpl00520 mpl00052 mpl01250 mpl01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:mpl00520 mpl01250 mpl01100]
M00012 Glyoxylate cycle [PATH:mpl00630 mpl01200 mpl01100 mpl01110]
M00982 Methylcitrate cycle [PATH:mpl00640 mpl00020 mpl01200]
M00968 Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:mpl00030 mpl00230 mpl00240 mpl00630 mpl01100]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:mpl00620 mpl00710 mpl01200 mpl01100 mpl01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:mpl00620 mpl00720 mpl01200 mpl01100 mpl01120]
M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate [PATH:mpl00720 mpl01200 mpl01100 mpl01120]

Methane metabolism
M00567 Methanogenesis, CO2 => methane [PATH:mpl00680 mpl01200 mpl01100 mpl01120]
M00357 Methanogenesis, acetate => methane [PATH:mpl00680 mpl01200 mpl01100 mpl01120]
M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate [PATH:mpl00300 mpl00680 mpl01210 mpl01230 mpl01240 mpl01100 mpl01120]
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:mpl00030 mpl00680 mpl01200 mpl01230 mpl01100 mpl01120]
M00378 F420 biosynthesis, archaea [PATH:mpl00680 mpl01240 mpl01100 mpl01120]

Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:mpl00910 mpl01100 mpl01120]

Sulfur metabolism
M00985 Sulfide oxidation, sulfide => sulfur [PATH:mpl00920]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:mpl00190 mpl01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:mpl00190 mpl01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:mpl00190 mpl01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:mpl00190 mpl01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:mpl00190 mpl01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:mpl00190 mpl01100]
M00159 V/A-type ATPase, prokaryotes [PATH:mpl00190 mpl01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:mpl00061 mpl01212 mpl01100]
M00083 Fatty acid biosynthesis, elongation [PATH:mpl00061 mpl01212 mpl01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:mpl00061 mpl00071 mpl01212 mpl01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:mpl00564 mpl01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mpl00230 mpl01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mpl00230 mpl01232 mpl01240 mpl01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mpl00230 mpl01232 mpl01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mpl00230 mpl00240 mpl01232 mpl01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:mpl00230 mpl01232 mpl01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:mpl00230 mpl01232 mpl01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:mpl00240 mpl01240 mpl01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:mpl00240 mpl01232 mpl01240 mpl01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:mpl00240 mpl01232 mpl01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:mpl00240 mpl00410 mpl00770 mpl01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:mpl00260 mpl00680 mpl01200 mpl01230 mpl01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:mpl00260 mpl01230 mpl01100 mpl01110]
M00621 Glycine cleavage system [PATH:mpl00260 mpl00630 mpl00670 mpl00785 mpl01200 mpl01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:mpl00270 mpl00920 mpl01200 mpl01230 mpl01100 mpl01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:mpl00260 mpl00270 mpl00670 mpl01230 mpl01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:mpl00270 mpl01230 mpl01100]
M00035 Methionine degradation [PATH:mpl00270 mpl00670 mpl01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:mpl00290 mpl00770 mpl01210 mpl01230 mpl01100 mpl01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:mpl00290 mpl01230 mpl01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:mpl00290 mpl01210 mpl01230 mpl01100 mpl01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:mpl00300 mpl01230 mpl01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:mpl00300 mpl01230 mpl01100 mpl01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:mpl00220 mpl01210 mpl01230 mpl01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:mpl00220 mpl01230 mpl01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:mpl00330 mpl01230 mpl01100]
M00970 Proline degradation, proline => glutamate [PATH:mpl00330 mpl01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:mpl00330 mpl01100]

Polyamine biosynthesis
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mpl00330 mpl01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:mpl00340 mpl01230 mpl01100 mpl01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:mpl00340 mpl01100]

Aromatic amino acid metabolism
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:mpl00400 mpl01230 mpl01100 mpl01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:mpl00400 mpl01230 mpl01100 mpl01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:mpl00400 mpl01230 mpl01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:mpl00350 mpl01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:mpl00250 mpl00650 mpl01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:mpl00480 mpl01240 mpl01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:mpl01250 mpl01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:mpl00730 mpl01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:mpl00750 mpl01240 mpl01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:mpl00760 mpl01240 mpl01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:mpl00770 mpl01240 mpl01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:mpl00780 mpl01240 mpl01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:mpl00785 mpl01240 mpl01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:mpl00790 mpl00670 mpl01240 mpl01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:mpl00790 mpl01240 mpl01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:mpl00860 mpl01240 mpl01100 mpl01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:mpl00860 mpl01240 mpl01100 mpl01110]
M00847 Heme biosynthesis, archaea, siroheme => heme [PATH:mpl00860 mpl01240 mpl01100 mpl01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:mpl00860 mpl01240 mpl01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:mpl01240 mpl01100 mpl01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:mpl00900 mpl01100 mpl01110]
M00849 C5 isoprenoid biosynthesis, mevalonate pathway, archaea [PATH:mpl00900 mpl01100 mpl01110]
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:mpl00900 mpl01100 mpl01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:mpl00900 mpl01100 mpl01110]
M00365 C10-C20 isoprenoid biosynthesis, archaea [PATH:mpl00900 mpl01100 mpl01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:mpl00521 mpl00523 mpl01250 mpl01100 mpl01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00617 Methanogen