KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:rso00010 rso01200 rso01230 rso01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:rso00010 rso00020 rso01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:rso00010 rso00020 rso00620 rso00785 rso01200 rso01210 rso01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:rso00020 rso01200 rso01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:rso00020 rso01200 rso01210 rso01230 rso01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:rso00020 rso01200 rso01210 rso01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:rso00030 rso01200 rso01230 rso01100 rso01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:rso00030 rso00230 rso01200 rso01230 rso01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:rso00030 rso01200 rso01100 rso01120]

Other carbohydrate metabolism
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:rso00052 rso01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:rso00520 rso01250 rso01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:rso00520 rso01250 rso01100]
M00012 Glyoxylate cycle [PATH:rso00630 rso01200 rso01100 rso01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:rso00620 rso00710 rso01200 rso01100 rso01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:rso00910 rso01100 rso01120]

Sulfur metabolism
M00595 Thiosulfate oxidation by SOX complex, thiosulfate => sulfate [PATH:rso00920 rso01100 rso01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:rso00190 rso01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:rso00190 rso01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:rso00190 rso01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:rso00190 rso01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:rso00190 rso01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:rso00190 rso01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:rso00190 rso01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:rso00061 rso01212 rso01100]
M00083 Fatty acid biosynthesis, elongation [PATH:rso00061 rso01212 rso01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:rso00061 rso00071 rso01212 rso01100]
M00087 beta-Oxidation [PATH:rso00071 rso01212 rso01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:rso00564 rso01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rso00230 rso01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rso00230 rso01232 rso01240 rso01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rso00230 rso01232 rso01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rso00230 rso00240 rso01232 rso01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:rso00230 rso01232 rso01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:rso00230 rso01232 rso01100]
M00546 Purine degradation, xanthine => urea [PATH:rso00230 rso01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:rso00240 rso01232 rso01240 rso01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:rso00240 rso01232 rso01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:rso00260 rso00680 rso01200 rso01230 rso01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:rso00260 rso01230 rso01100 rso01110]
M00621 Glycine cleavage system [PATH:rso00260 rso00630 rso00785 rso01200 rso01100]
M00975 Betaine degradation, bacteria, betaine => pyruvate [PATH:rso00260 rso01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:rso00270 rso00920 rso01200 rso01230 rso01100 rso01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:rso00270 rso01230 rso01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:rso00290 rso00770 rso01210 rso01230 rso01100 rso01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:rso00290 rso01230 rso01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:rso00290 rso01210 rso01230 rso01100 rso01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:rso00280 rso01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:rso00300 rso01230 rso01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:rso00220 rso01210 rso01230 rso01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:rso00220 rso01230 rso01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:rso00330 rso01230 rso01100]
M00970 Proline degradation, proline => glutamate [PATH:rso00330 rso01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:rso00330 rso01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:rso00340 rso01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:rso00400 rso01230 rso01100 rso01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:rso00400 rso01230 rso01100 rso01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:rso00400 rso01230 rso01100 rso01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:rso00400 rso01230 rso01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:rso00350 rso01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:rso00480 rso01240 rso01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:rso00540 rso01250 rso01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:rso00760 rso01240 rso01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:rso00770 rso01240 rso01100 rso01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:rso00770 rso01240 rso01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:rso00780 rso01240 rso01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:rso00785 rso01240 rso01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:rso00790 rso00670 rso01240 rso01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:rso00790 rso01240 rso01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:rso00860 rso01240 rso01100 rso01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:rso00860 rso01240 rso01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:rso00521 rso00523 rso00541 rso01250 rso01100 rso01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00638 Salicylate degradation, salicylate => gentisate [PATH:rso00626 rso01100 rso01120]

Gene set
Pathogenicity
Drug resistance
M00649 Multidrug resistance, efflux pump AdeABC [PATH:rso01501]
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity