KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sfr00010 sfr01200 sfr01230 sfr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sfr00010 sfr00020 sfr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sfr00010 sfr00020 sfr00620 sfr00785 sfr01200 sfr01210 sfr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sfr00020 sfr01200 sfr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sfr00020 sfr01200 sfr01210 sfr01230 sfr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sfr00020 sfr01200 sfr01210 sfr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sfr00030 sfr01200 sfr01100 sfr01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sfr00030 sfr01200 sfr01100 sfr01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sfr00030 sfr01200 sfr01230 sfr01100 sfr01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sfr00030 sfr00230 sfr01200 sfr01230 sfr01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:sfr00030 sfr01200 sfr01100 sfr01120]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sfr00500 sfr01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:sfr00521 sfr00523 sfr00541 sfr01250 sfr01100 sfr01110]
M00012 Glyoxylate cycle [PATH:sfr00630 sfr01200 sfr01100 sfr01110]
M00982 Methylcitrate cycle [PATH:sfr00640 sfr00020 sfr01200 sfr01100 sfr01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sfr00620 sfr00710 sfr01200 sfr01100 sfr01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sfr00430 sfr00620 sfr00720 sfr01200 sfr01100 sfr01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:sfr00910 sfr01310 sfr01100 sfr01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:sfr00920 sfr01100 sfr01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:sfr00190 sfr01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:sfr00190 sfr01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:sfr00190 sfr01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:sfr00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:sfr00190 sfr01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:sfr00190 sfr01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sfr00190 sfr01100]

Lipid metabolism
Fatty acid metabolism
M00083 Fatty acid biosynthesis, elongation [PATH:sfr00061 sfr01212 sfr01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sfr00061 sfr00071 sfr01212 sfr01100]
M00087 beta-Oxidation [PATH:sfr00071 sfr01212 sfr01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sfr00564 sfr01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sfr00230 sfr01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sfr00230 sfr01232 sfr01240 sfr01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sfr00230 sfr01232 sfr01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sfr00230 sfr00240 sfr01232 sfr01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sfr00240 sfr01232 sfr01240 sfr01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sfr00240 sfr01232 sfr01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sfr00260 sfr00680 sfr01200 sfr01230 sfr01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sfr00260 sfr01230 sfr01100 sfr01110]
M00621 Glycine cleavage system [PATH:sfr00260 sfr00630 sfr00670 sfr00785 sfr01200 sfr01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:sfr00260 sfr00670 sfr01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sfr00270 sfr00920 sfr01200 sfr01230 sfr01100 sfr01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:sfr00270 sfr01230 sfr01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sfr00290 sfr00770 sfr01210 sfr01230 sfr01100 sfr01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sfr00290 sfr01230 sfr01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sfr00290 sfr01210 sfr01230 sfr01100 sfr01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:sfr00280 sfr01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sfr00300 sfr01230 sfr01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sfr00220 sfr01210 sfr01230 sfr01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:sfr00330 sfr01230 sfr01100]
M00970 Proline degradation, proline => glutamate [PATH:sfr00330 sfr01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sfr00340 sfr01230 sfr01100 sfr01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sfr00340 sfr01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sfr00400 sfr01230 sfr01100 sfr01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sfr00400 sfr01230 sfr01100 sfr01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:sfr00400 sfr01230 sfr01100 sfr01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:sfr00400 sfr01230 sfr01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:sfr00350 sfr01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:sfr00480 sfr01240 sfr01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:sfr00540 sfr01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:sfr00540 sfr01250 sfr01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:sfr00730 sfr01240 sfr01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sfr00740 sfr01240 sfr01100 sfr01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:sfr00750 sfr01240 sfr01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sfr00760 sfr01240 sfr01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sfr00770 sfr01240 sfr01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sfr00780 sfr01240 sfr01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sfr00785 sfr01240 sfr01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:sfr00790 sfr00670 sfr01240 sfr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sfr00790 sfr01240 sfr01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:sfr00860 sfr01240 sfr01100 sfr01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:sfr00860 sfr01240 sfr01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:sfr00130 sfr01240 sfr01100 sfr01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:sfr00130 sfr01240]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:sfr00130 sfr01240 sfr01100 sfr01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity