KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:shab00010 shab01200 shab01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:shab00010 shab01200 shab01230 shab01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:shab00010 shab00020 shab01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:shab00010 shab00020 shab00620 shab01200 shab01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:shab00020 shab01200 shab01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:shab00020 shab01200 shab01210 shab01230 shab01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:shab00020 shab01200 shab01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:shab00030 shab01200 shab01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:shab00030 shab01200 shab01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:shab00030 shab01200 shab01230 shab01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:shab00030 shab00230 shab01200 shab01230 shab01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:shab00040 shab01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:shab00052 shab01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:shab00040 shab00053 shab01240 shab01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:shab00500 shab01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:shab00500 shab01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:shab00520 shab01250 shab01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:shab00520 shab00052 shab01250 shab01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:shab00520 shab01250 shab01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:shab00280 shab00630 shab00640 shab01200 shab01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:shab00562 shab01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:shab00562 shab01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:shab00562 shab01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:shab00190]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:shab00190]
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:shab00190]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:shab00190]
M00152 Cytochrome bc1 complex [PATH:shab00190]
M00160 V-type ATPase, eukaryotes [PATH:shab00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:shab00061 shab01212 shab01100]
M00083 Fatty acid biosynthesis, elongation [PATH:shab00061 shab01212 shab01100]
M00085 Fatty acid elongation in mitochondria [PATH:shab00062 shab01212 shab01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:shab00062 shab01040 shab01212 shab01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:shab00061 shab00071 shab01212 shab01100]
M00087 beta-Oxidation [PATH:shab00071 shab01212 shab01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:shab01040 shab01212 shab01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol [PATH:shab00100 shab01100]
M00103 Cholecalciferol biosynthesis [PATH:shab00100 shab01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH:shab00120 shab01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:shab00140 shab01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:shab00140 shab01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:shab00561 shab01100]
M00098 Acylglycerol degradation [PATH:shab00561 shab01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:shab00564 shab01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:shab00564 shab01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:shab00564 shab01100]
M00094 Ceramide biosynthesis [PATH:shab00600 shab01100]
M00066 Lactosylceramide biosynthesis [PATH:shab00600 shab01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:shab00600 shab00565 shab01100]
M00099 Sphingosine biosynthesis [PATH:shab00600 shab01100]
M00100 Sphingosine degradation [PATH:shab00600 shab01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:shab00230 shab01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:shab00230 shab01232 shab01240 shab01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:shab00230 shab01232 shab01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:shab00230 shab00240 shab01232 shab01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:shab00230 shab01232 shab01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:shab00230 shab01232 shab01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:shab00240 shab01240 shab01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:shab00240 shab01232 shab01240 shab01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:shab00240 shab01232 shab01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:shab00240 shab00410 shab00770 shab01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:shab00260 shab01200 shab01230 shab01100]
M00621 Glycine cleavage system [PATH:shab00260 shab00630 shab01200 shab01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:shab00260 shab01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:shab00260 shab00270 shab01230 shab01100]
M00034 Methionine salvage pathway [PATH:shab00270 shab01100]
M00035 Methionine degradation [PATH:shab00270 shab01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:shab00280 shab01100]

Lysine metabolism
Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:shab00220 shab01230 shab01100]
M00029 Urea cycle [PATH:shab00220 shab01230 shab01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:shab00330 shab01230 shab01100]
M00970 Proline degradation, proline => glutamate [PATH:shab00330 shab01100]
M00972 Proline metabolism [PATH:shab00330]
M00047 Creatine pathway [PATH:shab00330 shab01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:shab00330 shab01100]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:shab00330 shab01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:shab00330 shab01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:shab00340 shab01100]

Aromatic amino acid metabolism
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:shab00350 shab01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:shab00350 shab01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:shab00350 shab01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:shab00380 shab01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:shab00380 shab01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:shab00250 shab00650 shab01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:shab00480 shab01240 shab01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:shab00510 shab01100]
M00075 N-glycan biosynthesis, complex type [PATH:shab00510 shab01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:shab00563 shab01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:shab00601 shab01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:shab00601 shab01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:shab00603 shab01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:shab00604 shab01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:shab00532 shab00534 shab01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:shab00532 shab01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:shab00534 shab01100]
M00076 Dermatan sulfate degradation [PATH:shab00531 shab01100]
M00077 Chondroitin sulfate degradation [PATH:shab00531 shab01100]
M00078 Heparan sulfate degradation [PATH:shab00531 shab01100]
M00079 Keratan sulfate degradation [PATH:shab00531 shab01100]

Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:shab00770 shab01240 shab01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:shab00785 shab01240 shab01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:shab00785 shab01240 shab01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:shab00790 shab01240 shab01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:shab00790 shab01240 shab01100]
M00141 C1-unit interconversion, eukaryotes [PATH:shab00670 shab01240 shab01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:shab00860 shab01240 shab01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:shab00130 shab01240 shab01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:shab00900 shab01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:shab00900 shab01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity