KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sme00010 sme01200 sme01230 sme01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sme00010 sme00020 sme01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sme00010 sme00020 sme00620 sme01200 sme01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sme00020 sme01200 sme01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sme00020 sme01200 sme01210 sme01230 sme01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sme00020 sme01200 sme01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sme00030 sme01200 sme01100 sme01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sme00030 sme01200 sme01100 sme01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sme00030 sme01200 sme01230 sme01100 sme01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sme00030 sme00230 sme01200 sme01230 sme01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:sme00030 sme01200 sme01100 sme01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:sme00040 sme00030 sme01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:sme00052 sme01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sme00500 sme01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:sme00500 sme01100 sme01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sme00520 sme01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sme00520 sme01100]
M00012 Glyoxylate cycle [PATH:sme00630 sme01200 sme01100 sme01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sme00280 sme00630 sme00640 sme01200 sme01100]

Energy metabolism
Carbon fixation
M00166 Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P [PATH:sme00710 sme01200 sme01100 sme01120]
M00169 CAM (Crassulacean acid metabolism), light [PATH:sme00620 sme00710 sme01200 sme01100 sme01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sme00430 sme00620 sme01200 sme01100 sme01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:sme00910 sme01100 sme01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:sme00910 sme01100 sme01120]
M00529 Denitrification, nitrate => nitrogen [PATH:sme00910 sme01100 sme01120]

Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:sme00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH:sme00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:sme00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:sme00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:sme00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:sme00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sme00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sme00061 sme01212 sme01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sme00061 sme01212 sme01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sme00061 sme00071 sme01212 sme01100]
M00087 beta-Oxidation [PATH:sme00071 sme01212 sme01100]

Sterol biosynthesis
Lipid metabolism
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:sme00564 sme01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sme00564 sme01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:sme00230 sme01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sme00230 sme01240 sme01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:sme00230 sme01100]
M00546 Purine degradation, xanthine => urea [PATH:sme00230 sme01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sme00240 sme01240 sme01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:sme00240 sme01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sme00260 sme00680 sme01200 sme01230 sme01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sme00260 sme01230 sme01100 sme01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:sme00260 sme01100]
M00919 Ectoine degradation, ectoine => aspartate [PATH:sme00260 sme01100 sme01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sme00270 sme00920 sme01200 sme01230 sme01100 sme01110]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:sme00270 sme01230 sme01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sme00290 sme00770 sme01210 sme01230 sme01100 sme01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sme00290 sme01230 sme01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sme00290 sme01210 sme01230 sme01100 sme01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:sme00280 sme01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sme00300 sme01230 sme01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sme00220 sme01210 sme01230 sme01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:sme00220 sme01230 sme01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:sme00330 sme01230 sme01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:sme00330 sme01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sme00340 sme01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sme00400 sme01230 sme01100 sme01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sme00400 sme01230 sme01100 sme01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:sme00400 sme01230 sme01100 sme01110]
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:sme00400 sme01230 sme01100 sme01110]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:sme00350 sme01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:sme00480 sme01240 sme01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sme00760 sme01240 sme01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sme00770 sme01240 sme01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sme00785 sme01240 sme01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:sme00790 sme00670 sme01240 sme01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sme00790 sme01240 sme01100]
M00140 C1-unit interconversion, prokaryotes [PATH:sme00670 sme01240 sme01100]
M00925 Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide [PATH:sme00860 sme01240 sme01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:sme00521 sme00523 sme00541 sme01100 sme01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
M00664 Nodulation

Module set
Metabolic capacity