KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sscv00010 sscv01200 sscv01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sscv00010 sscv01200 sscv01230 sscv01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sscv00010 sscv00020 sscv01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sscv00010 sscv00020 sscv00620 sscv01200 sscv01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sscv00020 sscv01200 sscv01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sscv00020 sscv01200 sscv01210 sscv01230 sscv01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sscv00020 sscv01200 sscv01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sscv00030 sscv01200 sscv01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sscv00030 sscv00230 sscv01200 sscv01230 sscv01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:sscv00040 sscv01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sscv00500 sscv01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:sscv00500 sscv01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sscv00520 sscv01250 sscv01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:sscv00520 sscv01250 sscv01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sscv00280 sscv00630 sscv00640 sscv01200 sscv01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:sscv00562 sscv01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:sscv00562 sscv01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:sscv00562 sscv01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:sscv00190]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:sscv00190]
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:sscv00190]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:sscv00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:sscv00190]
M00152 Cytochrome bc1 complex [PATH:sscv00190]
M00154 Cytochrome c oxidase [PATH:sscv00190]
M00160 V-type ATPase, eukaryotes [PATH:sscv00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sscv00061 sscv01212 sscv01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sscv00061 sscv01212 sscv01100]
M00085 Fatty acid elongation in mitochondria [PATH:sscv00062 sscv01212 sscv01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:sscv00062 sscv01040 sscv01212 sscv01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sscv00061 sscv00071 sscv01212 sscv01100]
M00087 beta-Oxidation [PATH:sscv00071 sscv01212 sscv01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:sscv01040 sscv01212 sscv01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol [PATH:sscv00100 sscv01100]
M00103 Cholecalciferol biosynthesis [PATH:sscv00100 sscv01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:sscv00140 sscv01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH:sscv00140 sscv01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:sscv00140 sscv01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:sscv00561 sscv01100]
M00098 Acylglycerol degradation [PATH:sscv00561 sscv01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:sscv00564 sscv01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:sscv00564 sscv01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:sscv00564 sscv01100]
M00094 Ceramide biosynthesis [PATH:sscv00600 sscv01100]
M00066 Lactosylceramide biosynthesis [PATH:sscv00600 sscv01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:sscv00600 sscv00565 sscv01100]
M00099 Sphingosine biosynthesis [PATH:sscv00600 sscv01100]
M00100 Sphingosine degradation [PATH:sscv00600 sscv01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sscv00230 sscv01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sscv00230 sscv01232 sscv01240 sscv01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sscv00230 sscv01232 sscv01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sscv00230 sscv00240 sscv01232 sscv01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:sscv00230 sscv01232 sscv01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:sscv00230 sscv01232 sscv01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:sscv00240 sscv01240 sscv01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sscv00240 sscv01232 sscv01240 sscv01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sscv00240 sscv01232 sscv01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:sscv00240 sscv00410 sscv00770 sscv01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sscv00260 sscv01200 sscv01230 sscv01100]
M00621 Glycine cleavage system [PATH:sscv00260 sscv00630 sscv01200 sscv01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:sscv00260 sscv01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:sscv00260 sscv00270 sscv01230 sscv01100]
M00034 Methionine salvage pathway [PATH:sscv00270 sscv01100]
M00035 Methionine degradation [PATH:sscv00270 sscv01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:sscv00280 sscv01100]

Lysine metabolism
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:sscv00310 sscv01100]

Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH:sscv00330 sscv01230 sscv01100]
M00970 Proline degradation, proline => glutamate [PATH:sscv00330 sscv01100]
M00972 Proline metabolism [PATH:sscv00330]
M00047 Creatine pathway [PATH:sscv00330 sscv01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:sscv00330 sscv01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:sscv00330 sscv01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sscv00340 sscv01100]

Aromatic amino acid metabolism
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:sscv00350 sscv01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:sscv00350 sscv01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:sscv00350 sscv01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:sscv00380 sscv01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:sscv00380 sscv01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:sscv00250 sscv00650 sscv01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:sscv00480 sscv01240 sscv01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:sscv00510 sscv01100]
M00073 N-glycan precursor trimming [PATH:sscv00510 sscv01100]
M00075 N-glycan biosynthesis, complex type [PATH:sscv00510 sscv01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:sscv00515 sscv01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:sscv00563 sscv01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:sscv00601 sscv01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:sscv00601 sscv01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:sscv00604 sscv01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:sscv00532 sscv00534 sscv01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:sscv00532 sscv01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:sscv00534 sscv01100]
M00076 Dermatan sulfate degradation [PATH:sscv00531 sscv01100]
M00077 Chondroitin sulfate degradation [PATH:sscv00531 sscv01100]
M00078 Heparan sulfate degradation [PATH:sscv00531 sscv01100]
M00079 Keratan sulfate degradation [PATH:sscv00531 sscv01100]

Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:sscv00380 sscv00760 sscv01240 sscv01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sscv00770 sscv01240 sscv01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:sscv00785 sscv01240 sscv01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:sscv00785 sscv01240 sscv01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:sscv00790 sscv01240 sscv01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sscv00790 sscv01240 sscv01100]
M00141 C1-unit interconversion, eukaryotes [PATH:sscv00670 sscv01240 sscv01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:sscv00860 sscv01240 sscv01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:sscv00900 sscv01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity