KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:vcy00010 vcy01200 vcy01230 vcy01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:vcy00010 vcy00020 vcy01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:vcy00010 vcy00020 vcy00620 vcy00785 vcy01200 vcy01210 vcy01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:vcy00020 vcy01200 vcy01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:vcy00020 vcy01200 vcy01210 vcy01230 vcy01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:vcy00020 vcy01200 vcy01210 vcy01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:vcy00030 vcy01200 vcy01100 vcy01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:vcy00030 vcy01200 vcy01100 vcy01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:vcy00030 vcy01200 vcy01230 vcy01100 vcy01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:vcy00030 vcy00230 vcy01200 vcy01230 vcy01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:vcy00052 vcy01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:vcy00500 vcy01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:vcy00500 vcy01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:vcy00520 vcy00052 vcy01250 vcy01100]
M00012 Glyoxylate cycle [PATH:vcy00630 vcy01200 vcy01100 vcy01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:vcy00620 vcy01200 vcy01100 vcy01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:vcy00430 vcy00620 vcy01200 vcy01100 vcy01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:vcy00910 vcy01100 vcy01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:vcy00920 vcy01100 vcy01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:vcy00190 vcy01100]
M00150 Fumarate reductase, prokaryotes [PATH:vcy00190 vcy01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:vcy00190 vcy01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:vcy00190 vcy01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:vcy00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:vcy00190 vcy01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:vcy00190 vcy01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:vcy00190 vcy01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:vcy00061 vcy01212 vcy01100]
M00083 Fatty acid biosynthesis, elongation [PATH:vcy00061 vcy01212 vcy01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:vcy00061 vcy00071 vcy01212 vcy01100]
M00087 beta-Oxidation [PATH:vcy00071 vcy01212 vcy01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:vcy00564 vcy01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vcy00230 vcy01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vcy00230 vcy01232 vcy01240 vcy01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vcy00230 vcy01232 vcy01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vcy00230 vcy00240 vcy01232 vcy01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:vcy00230 vcy01232 vcy01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:vcy00230 vcy01232 vcy01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:vcy00240 vcy01240 vcy01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:vcy00240 vcy01232 vcy01240 vcy01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:vcy00260 vcy00680 vcy01200 vcy01230 vcy01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:vcy00260 vcy01230 vcy01100 vcy01110]
M00621 Glycine cleavage system [PATH:vcy00260 vcy00630 vcy00785 vcy01200 vcy01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:vcy00260 vcy01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:vcy00270 vcy00920 vcy01200 vcy01230 vcy01100 vcy01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:vcy00270 vcy01230 vcy01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:vcy00290 vcy00770 vcy01210 vcy01230 vcy01100 vcy01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:vcy00290 vcy01230 vcy01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:vcy00290 vcy01210 vcy01230 vcy01100 vcy01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:vcy00300 vcy01230 vcy01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:vcy00220 vcy01210 vcy01230 vcy01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:vcy00220 vcy01230 vcy01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:vcy00330 vcy01230 vcy01100]
M00970 Proline degradation, proline => glutamate [PATH:vcy00330 vcy01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:vcy00340 vcy01230 vcy01100 vcy01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:vcy00340 vcy01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:vcy00400 vcy01230 vcy01100 vcy01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:vcy00400 vcy01230 vcy01100 vcy01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:vcy00400 vcy01230 vcy01100 vcy01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:vcy00400 vcy01230 vcy01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:vcy00350 vcy01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:vcy00480 vcy01240 vcy01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:vcy00470 vcy01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:vcy00540 vcy01100]
M00063 CMP-KDO biosynthesis [PATH:vcy00540 vcy01250 vcy01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:vcy00540 vcy01250 vcy01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:vcy00740 vcy01240 vcy01100 vcy01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:vcy00750 vcy01240 vcy01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:vcy00760 vcy01240 vcy01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:vcy00770 vcy01240 vcy01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:vcy00780 vcy01240 vcy01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:vcy00785 vcy01240 vcy01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:vcy00790 vcy00670 vcy01240 vcy01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:vcy00790 vcy01240 vcy01100]
M00140 C1-unit interconversion, prokaryotes [PATH:vcy00670 vcy01240 vcy01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:vcy00860 vcy01240 vcy01100 vcy01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:vcy00860 vcy01240 vcy01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:vcy00130 vcy01240 vcy01100 vcy01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:vcy00130 vcy01240 vcy01100 vcy01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00918 Aerobactin biosynthesis, lysine => aerobactin [PATH:vcy00997 vcy01100 vcy01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00642 Multidrug resistance, efflux pump MexJK-OprM

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity