Dioxygenases Dioxygenases| OT | RM | Module | Enzyme | Dihydroxylation | Cleavage |
Post-processing | |||||||||
| 1.14.12 | Ferredoxin | 1.18.1 | 1.3.1 | 1.13.11 | |||||||||||
| OT | RM004 | M00545 | map00360 | 1.14.12.19 | 3-phenylpropionate/trans-cinnamate dioxygenase | K05708 hcaE |
K05709 hcaF |
K05710 hcaC |
K00529 hcaD |
K05711 hcaB |
K05713 mhpB |
K05714 mhpC |
K02554 mhpD |
K01666 mhpE |
K04073 mhpF |
| OT | RM004 | M00539 | map00622 | 1.14.12.25 | p-cumate 2,3-dioxygenase | K10619 cmtAb |
K16303 cmtAc |
K16304 cmtAd |
K18227 cmtAa |
K10620 cmtB |
K10621 cmtC |
K10622 cmtD |
K10623 cmtE |
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| OT | RM005 | M00551 | map00362 map00622 |
1.14.12.10 | benzoate/toluate 1,2-dioxygenase | K05549 benA xylX |
K05550 benB xylY |
K05784 benC xylZ |
K05783 benD xylL |
K00446 dmpB xylE |
K10216 dmpD xylF |
K18364 bphH xylJ |
K18365 bphI xylK |
K18366 bphJ xylQ |
|
| OT | RG002 | map00627 | 1.14.12.1 | anthranilate 1,2-dioxygenase | K05599 antA |
K05600 antB |
K11311 antC |
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| OT | RG002 | map00627 | 1.14.12.1 | anthranilate 1,2-dioxygenase | K16319 andAc |
K16320 andAd |
K18248 andAb |
K18249 andAa |
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| OT | RM004 | M00547 | map00362 map00623 |
1.14.12.3 1.14.12.11 |
benzene/toluene/chlorobenzene dioxygenase | K03268 todC1 tcbAa |
K16268 todC2 tcbAb |
K18089 todB tcbAc |
K18090 todA tcbAd |
K16269 todD tcbB |
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| OT | RM004 | map00642 | 1.14.12.- | ethylbenzene dioxygenase | K14748 etbAa |
K14749 etbAb |
K14750 etbAc |
K14751 etbC |
K18092 etbD |
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| OT | RM014 | M00534 | map00626 | 1.14.12.12 | naphthalene 1,2-dioxygenase | K14579 nahAc ndoB |
K14580 nahAd ndoC |
K14578 nahAb ndoA |
K14581 nahAa ndoR |
K14582 nahB doxE |
K14583 nahC |
K14584 nahD |
K14585 nahE |
K00152 nahF |
|
| 1.14.13.172 | salicylate 5-hydroxylase | K18242 nagG |
K18243 nagH |
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| OT | RM005 | M00624 | map00624 | 1.14.12.15 | terephthalate 1,2-dioxygenase | K18074 tphA2 |
K18075 tphA3 |
K18077 tphA1 |
K18076 tphB |
K04100 ligA K04101 ligB K00448 pcaG K00449 pcaH |
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| OT | RM004 | M00623 | map00624 | 1.14.12.7 | phthalate 4,5-dioxygenase | K18068 pht3 |
K18069 pht2 |
K18067 pht4 |
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| OT | RM004 | M00636 | map00624 | 1.14.12.- | phthalate 3,4-dioxygenase | K18251 phtAa |
K18252 phtAb |
K18253 phtAc |
K18254 phtAd |
K18255 phtB |
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| OT | RM004 | M00543 | map00621 | 1.14.12.18 | biphenyl 2,3-dioxygenase | K08689 bphAa |
K15750 bphAb |
K18087 bphAc |
K18088 bphAd |
K08690 bphB |
K00462 bphC |
K10222 bphD |
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| OT | RG002 | map00621 | 1.14.12.22 | carbazole 1,9a-dioxygenase | K15751 carAa |
K15752 carAc |
K15753 carAd |
K15754 carBa K15755 carBb |
K15756 carC |
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| Reaction modules |
|
| RM004 | Dihydroxylation of aromatic ring, type 1 (dioxygenase and dehydrogenase reactions) |
| RM005 | Dihydroxylation of aromatic ring, type 1a (dioxygenase and decarboxylating dehydrogenase reactions) |
| RM902 | Dihydroxylation of aromatic ring, type 1b (single dioxygenase reaction) |
| 1.14.12 | 1.3.1 | ||||
| RM004 | benzene |
RC00951 → |
RC00386 → |
catechol |
|
| RM005 | benzoate |
RC00270 → |
RC00271 → |
catechol |
|
| RG002 | anthranilate |
RC00192 → |
catechol |
| RM009 | Meta-cleavage of dihydroxylated aromatic ring |
| RM008 | Ortho-cleavage of dihydroxylated aromatic ring |