| Entry | The KEGG GENES database contains gene catalogs of complete genomes generated from RefSeq and other public resources and annotated with the KEGG Orthology (KO) system. Each entry is identified by the entry name or the accession number given by the original database, such as LocusTag or GeneID identifier. This is followed by distinction between a protein-coding gene (CDS) or an RNA-coding gene (tRNA, rRNA, etc.), and the organism identifier (T number) linking to the KEGG GENOME entry. |
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| Gene name | Gene name(s) where the primary gene name shown first can be used as an alternative identifier (in place of the accession number) to retrieve the entry. |
| Definition | Description of the gene or its product given by the original database. The annotation given by KEGG is shown in the next "KO" field. Note that the original annotaion is not modified even if it contradicts to the KEGG annotation. |
| KO | The KO (KEGG Orthology) system is the basis for cross-species annotation in KEGG, which assigns the KO identifier called the K number representing a functional ortholog that corresponds to a KEGG pathway node or a BRITE hierarchy node. Thus, a set of genes in the genome with assigned K numbers can be mapped to KEGG reference pathways and BRITE reference hierarchies to generate organism-specific pathways and hierarchies. In KEGG the EC numbers are attributes of the K numbers, and they are indirectly assigned through the KO system. |
| Organism | The KEGG organism name. |
| Pathway | KEGG pathways to which the gene has been mapped through the KO system, suggesting functional roles of the gene product in the context of molecular networks. By clicking on the link, the rectangular object of this gene product is marked red in the pathway map. |
| Module | KEGG modules (complete modules only) to which the gene has been mapped through the KO system, suggesting functional roles of the gene product in the context of molecular networks. By clicking on the link, the rectangular object of this gene product is marked red in the module map. |
| Network | KEGG networks that contain this gene or its variant. |
| Disease | Known association to diseases as stored in the KEGG DISEASE database. |
| Drug target | Known drugs that target this gene product as stored in the KEGG DRUG database. |
| Brite | Hierarchical classification of gene functions according to the KO system, as well as protein families and other classifications in the BRITE database. The BRITE hierarchy button may also be used to display these classifications with additional links. |
| SSDB | The KEGG SSDB database contains computational results of pairwise genome comparisons for all protein-coding genes in KEGG GENES. The Ortholog link generates possible orthologs based on the information about best-best hits and best hits determined by the rigorous Smith-Waterman algorithm (SSEARCH program). The Paralog link generates possible paralogs. The default threshold of the SW-score is 100 in both cases. The Gene Cluster link is a particularly useful tool for surveying conserved gene clusters (operon-like structures) in prokaryotic genomes. The GFIT link displays a read-only version of the KEGG annotation tool GFIT. |
| Motif | Pfam and PROSITE domains, which are precomputed and stored in the KEGG SSDB database. |
| Other DBs | Links to the outside database resources. |
| LinkDB | 'All DBs' button in this field retrieves all available links to related database entries in the LinkDB system. At GenomeNet this field does not appear; instead a list of actual links is displayed on the right. |
| Position | The chromosomal position of the gene and, when all the nucleotide positions are known, the link to the KEGG genome map browser. |
| AA seq | The number of amino acids and the sequence data. The AA seq link generates the sequence data in the FASTA format. The DB search link can be used for sequence similarity search by BLAST or FASTA against various databases. |
| NT seq | The number of nucleotides and the sequence data. The NT seq link generates the sequence data of the coding region and flanking regions in the FASTA format. |