KEGG    Network variation - NOTCH signaling
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ENTRYnt06511
NameNOTCH signaling
CategoryPathway view; Signal transduction
Pathwayhsa04330 Notch signaling pathway
Display drug-target relation   disease type
N00086      (DLL,JAG)NOTCH(NICD+RBPJ)(HES1,HEY1)
    SCDO1   DLL3*
    AOS6   DLL4*
    TOF/ALGS1   JAG1*
    AOVD1/AOS5     NOTCH1*
    HJCYS/ALGS2     NOTCH2*
    IFM2/CADASIL/LMS     NOTCH3*
    AOS3       RBPJ*
N00380    HPV E6JAG1NOTCH(NICD+RBPJ+MAML)(HES1,HEY1)
N00381    HPV E6MFNGNOTCH(NICD+RBPJ+MAML)(HES1,HEY1)
N00382    HPV E6(NFX1+PSEN1)NOTCH(NICD+RBPJ+MAML)(HES1,HEY1)
 
N01478    NOTCHADAM17(PSEN+PSENEN+NCSTN..NICD
    NISBD1   ADAM17*
    ACNINV1     NCSTN*
    ACNINV2     PSENEN*
    ACNINV3     PSEN1*
 
N01479    (MIB,NEUR)(DLL,JAG)
    LVNC7 MIB1*
 
N01480    (NICD+RBPJ)HES7LFNG
    SCDO4   HES7*
    SCDO3   LNFG*
N01481    (NICD+RBPJ+TBX6)MESP2(RIPPLY2,LFNG,EPHA..
    SCDO5 TBX6*
    SCDO2   MESP2*
    SCDO6     RIPPLY2*

Disease nameDisease category
SCDO1H00517Spondylocostal dysostosisCongenital malformation
AOS6H01413Adams-Oliver syndromeCongenital malformation
TOF/ALGS1H00549Tetralogy of FallotCongenital malformation
H00551Alagille syndromeCongenital malformation
AOVD1/AOS5H00554Aortic valve diseaseCongenital malformation
H01413Adams-Oliver syndromeCongenital malformation
HJCYS/ALGS2H00623Hajdu-Cheney syndromeMusculoskeletal disease
H00551Alagille syndromeCongenital malformation
IFM2/CADASIL/LMSH01910Infantile myofibromatosisNeoplasm
H00536Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)Congenital malformation
H01893Lateral meningocele syndromeCongenital malformation
AOS3H01413Adams-Oliver syndromeCongenital malformation
HPVH00030Cervical cancerCancer
NISBD1H02467Neonatal inflammatory skin and bowel diseaseImmune system disease
ACNINV1H00681Acne inversaSkin disease
ACNINV2H00681Acne inversaSkin disease
ACNINV3H00681Acne inversaSkin disease
LVNC7H01216Left ventricular noncompactionCardiovascular disease
SCDO4H00517Spondylocostal dysostosisCongenital malformation
SCDO3H00517Spondylocostal dysostosisCongenital malformation
SCDO5H00517Spondylocostal dysostosisCongenital malformation
SCDO2H00517Spondylocostal dysostosisCongenital malformation
SCDO6H00517Spondylocostal dysostosisCongenital malformation