# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Janthinobacterium.2805 Janthinobacterium_sp_.2882 jaz.411 jaz:YQ44_02040 bacillolysin family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Janthinobacterium.2805 Janthinobacterium_sp_.2882 jal.4927 jal:BZG29_25565 bacillolysin family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Janthinobacterium.2805 - jsv.4914 jsv:CNX70_25880 bacillolysin family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Janthinobacterium.15643 - jag.5034 jag:GJA_661 thermolysin metallopeptidase, catalytic domain protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.2334 - mass.382 mass:CR152_01185 bacillolysin family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.2335 Massilia_sp_.3431 masw.2016 masw:AM586_10470 hypothetical protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.2336 - mass.5274 mass:CR152_28590 peptidase M4 family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.2337 Massilia_sp_.12945 mnr.3862 mnr:ACZ75_20960 hypothetical protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.2338 - mtim.756 mtim:DIR46_04030 peptidase M4 family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.6222 Massilia_sp_.725 masy.24 masy:DPH57_16640 M4 family peptidase OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.6222 Massilia_sp_.725 masy.24 masy:DPH57_16645 M4 family peptidase OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.6222 - masz.1014 masz:C9I28_05245 bacillolysin family protein OC.120019 Bacteria.4190 Proteobacteria.209985 Betaproteobacteria.110425 Massilia.11951 Massilia_sp_.13166 mnr.4197 mnr:ACZ75_22705 bacillolysin family protein OC.120020 Bacteria.22329 Proteobacteria.160174 Gammaproteobacteria.186013 Shewanella.20077 - svo.2124 svo:SVI_2120 thermolysin metallopeptidase family OC.120020 Bacteria.22329 Proteobacteria.160174 Gammaproteobacteria.186013 Pseudoalteromonas.23593 - ptu.3994 ptu:PTUN_b0532 hypothetical protein OC.120020 Bacteria.22329 Proteobacteria.160174 Gammaproteobacteria.369753 Shewanella.9048 - shl.3430 shl:Shal_3483 peptidase M4 thermolysin OC.120020 Bacteria.22329 Proteobacteria.160174 Gammaproteobacteria.369753 Shewanella.9048 - svo.667 svo:SVI_0640 thermolysin metallopeptidase family OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.2316 - mxa.5913 mxa:MXAN_6106 fibA; matrix-associated zinc metalloprotease FibA; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.2316 - mfu.3143 mfu:LILAB_15735 matrix-associated zinc metalloprotease FibA; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.2316 - msd.6520 msd:MYSTI_06723 matrix-associated zinc metalloprotease FibA; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.2316 - mym.809 mym:A176_000783 Zinc metalloproteinase precursor; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.2316 - mmas.5756 mmas:MYMAC_005892 peptidase; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.2317 - msd.2731 msd:MYSTI_02756 matrix-associated zinc metalloprotease FibA; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.8656 - msd.713 msd:MYSTI_00607 M4 family peptidase; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.9729 - msd.3696 msd:MYSTI_03758 matrix-associated zinc metalloprotease FibA; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 Myxococcus.11719 - mxa.5258 mxa:MXAN_5442 peptidase, M4 (thermolysin) family OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccx.23 ccx:COCOR_05260 empA; virulence metalloprotease; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccx.23 ccx:COCOR_00680 fibA1; bacillolysin; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccx.884 ccx:COCOR_00799 npr; bacillolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccx.5554 ccx:COCOR_05722 nprV; neutral protease; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccx.6441 ccx:COCOR_06634 fibA; matrix-associated zinc metalloprotease FibA; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccx.6513 ccx:COCOR_06712 nprM1; bacillolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - sur.205 sur:STAUR_4897 fibA; Matrix-associated zinc metalloprotease FibA OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - sur.205 sur:STAUR_7459 Matrix-associated zinc metalloprotease FibA OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.58 age:AA314_05742 Zinc metalloproteinase precursor/aureolysin OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.58 age:AA314_09142 Zinc metalloproteinase precursor/aureolysin OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.58 age:AA314_04696 Zinc metalloproteinase precursor/aureolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.58 age:AA314_00679 Zinc metalloproteinase precursor/aureolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.58 age:AA314_08637 Zinc metalloproteinase precursor/aureolysin OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.59 age:AA314_05743 Zinc metalloproteinase precursor/aureolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.111 age:AA314_01740 Zinc metalloproteinase precursor/aureolysin; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.111 age:AA314_07697 Zinc metalloproteinase precursor/aureolysin; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.4208 age:AA314_04229 Zinc metalloproteinase precursor/aureolysin; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.5454 age:AA314_05554 Zinc metalloproteinase precursor/aureolysin; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - age.7946 age:AA314_08228 Zinc metalloproteinase precursor/aureolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - mbd.192 mbd:MEBOL_007739 hypothetical protein OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - mbd.192 mbd:MEBOL_007740 hypothetical protein OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - mbd.771 mbd:MEBOL_000619 peptidase M4; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - mbd.4148 mbd:MEBOL_004242 hypothetical protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - mbd.6046 mbd:MEBOL_006291 peptidase M4; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.209 cfus:CYFUS_002522 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.209 cfus:CYFUS_004891 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.332 cfus:CYFUS_007667 hypothetical protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.332 cfus:CYFUS_007200 hypothetical protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.985 cfus:CYFUS_000703 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.1314 cfus:CYFUS_001067 hypothetical protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.3069 cfus:CYFUS_003038 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.5400 cfus:CYFUS_005614 hypothetical protein OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.5490 cfus:CYFUS_005706 hypothetical protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.5894 cfus:CYFUS_006155 peptidase M4; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.6095 cfus:CYFUS_006373 peptidase M4; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.6917 cfus:CYFUS_007262 peptidase; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.7219 cfus:CYFUS_007593 hypothetical protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - cfus.9271 cfus:CYFUS_009809 peptidase S8; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.160174 Deltaproteobacteria.36816 - - ccro.7148 ccro:CMC5_077490 uncharacterized protein; K08604 vibriolysin [EC:3.4.24.25] OC.120020 Bacteria.22329 Proteobacteria.775904 Gammaproteobacteria.423827 - - hch.916 hch:HCH_00828 Zinc metalloprotease (elastase) OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 Hymenobacter_sp_.421 - hyd.141 hyd:PK28_00740 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 Hymenobacter_sp_.421 - hye.2816 hye:AM218_15305 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 Hymenobacter_sp_.6049 - hym.1884 hym:N008_09495 hypothetical protein OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 Hymenobacter_sp_.10350 - hyz.196 hyz:AXW84_00730 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 - - hsw.3978 hsw:Hsw_4005 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 - - hyg.42 hyg:AUC43_07375 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Hymenobacter.238 - - hyg.42 hyg:AUC43_07380 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Pontibacter.3127 - - pact.1116 pact:CA264_05485 T9SS C-terminal target domain-containing protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 - - - flm.3714 flm:MY04_3789 Peptidase family M4, thermolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Gramella.3498 - - gfl.1320 gfl:GRFL_1314 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Flavobacterium.3470 Flavobacterium_johnsoniae.4490 - fjo.1005 fjo:Fjoh_0886 peptidase family M4, thermolysin OC.120021 Bacteria.4192 Bacteroidetes.1690 Flavobacterium.3470 - - fco.1609 fco:FCOL_08450 peptidase M4, thermolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Flavobacterium.6116 - - fbr.2156 fbr:FBFL15_2351 Probable M4 thermolysin family metalloprotease precursor; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Flavobacterium.6116 - - fco.438 fco:FCOL_02025 thermolysin OC.120021 Bacteria.4192 Bacteroidetes.1690 Flavobacterium.6116 - - fin.521 fin:KQS_02660 Probable M4 thermolysin family metalloprotease precursor; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 - - - cat.715 cat:CA2559_03565 thermolysin OC.120021 Bacteria.4192 Bacteroidetes.1690 - - - cat.1779 cat:CA2559_09051 thermolysin OC.120021 Bacteria.4192 Bacteroidetes.1690 Maribacter.6757 Maribacter_sp_.6982 - mart.512 mart:BTR34_02515 hypothetical protein OC.120021 Bacteria.4192 Bacteroidetes.1690 - - - asl.1297 asl:Aeqsu_1324 Zinc metalloprotease (elastase); K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Chryseobacterium.6254 Chryseobacterium_sp_.4886 - chry.197 chry:CEY12_00875 peptidase M4; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 Tenacibaculum.8336 - - tmar.2628 tmar:MARIT_3129 Protein of unknown function precursor containing a C-terminal secretion signal. Putative peptidase M4 family OC.120021 Bacteria.4192 Bacteroidetes.1690 Lutibacter.2310 - - lul.2101 lul:LPB138_11060 hypothetical protein OC.120021 Bacteria.4192 Bacteroidetes.1690 Lutibacter.4163 - - lut.1692 lut:Lupro_08785 hypothetical protein OC.120021 Bacteria.4192 Bacteroidetes.1690 Olleya.3296 - - oll.724 oll:CW732_03570 peptidase M4; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 - - - fbu.15 fbu:UJ101_00424 nprB; neutral protease; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1690 - - - fbu.15 fbu:UJ101_00425 neutral protease OC.120021 Bacteria.4192 Bacteroidetes.1730 Tannerella.1750 - - tfo.677 tfo:BFO_0703 thermolysin metallopeptidase, catalytic domain protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1748 - - - fek.305 fek:C1H87_01055 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1762 Chryseobacterium.558 Chryseobacterium_sp_.6228 - chry.2080 chry:CEY12_10630 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1762 Chryseobacterium.558 Chryseobacterium_sp_.6229 - chry.2081 chry:CEY12_10635 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1762 Chryseobacterium.558 Chryseobacterium_sp_.10683 - chz.4098 chz:CHSO_4198 thermolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1762 Chryseobacterium.558 - - cio.2795 cio:CEQ15_14585 T9SS C-terminal target domain-containing protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1762 Chryseobacterium.558 - - cpip.55 cpip:CJF12_18165 T9SS C-terminal target domain-containing protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1762 Chryseobacterium.558 - - cpip.55 cpip:CJF12_18170 T9SS C-terminal target domain-containing protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1814 - - - eol.87 eol:Emtol_0024 peptidase M4 thermolysin; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1826 Echinicola.4649 - - evi.511 evi:Echvi_0463 Zinc metalloprotease (elastase) OC.120021 Bacteria.4192 Bacteroidetes.1836 Tannerella.2001 - - tfo.1084 tfo:BFO_1168 thermolysin metallopeptidase, catalytic domain protein; K01400 bacillolysin [EC:3.4.24.28] OC.120021 Bacteria.4192 Bacteroidetes.1848 - - - oho.2965 oho:Oweho_3122 Zinc metalloprotease (elastase); K01400 bacillolysin [EC:3.4.24.28] OC.120022 Bacteria.4665 Bacteroidetes.2422 Chryseobacterium.1811 Chryseobacterium_sp_.12518 - cih.3172 cih:ATE47_16555 hypothetical protein; K01400 bacillolysin [EC:3.4.24.28] OC.120022 Bacteria.4665 Bacteroidetes.2422 Chryseobacterium.1811 - - cio.1880 cio:CEQ15_09780 T9SS C-terminal target domain-containing protein; K01400 bacillolysin [EC:3.4.24.28]