# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.185835 Eukaryotes.693412 Plants.177858 Eudicots.210547 Pea_family.65001 - ccaj.6358 ccaj:109794539 uncharacterized protein LOC109794539 OC.185835 Bacteria.307954 Proteobacteria.235218 Gammaproteobacteria.186822 Vibrio.34687 - vta.3140 vta:A3175 hsdR; Type-1 restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.235218 Gammaproteobacteria.186822 Pseudoalteromonas.7491 - part.12 part:PARC_p0120 hsdR; type I restriction enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.235218 Gammaproteobacteria.186822 Pseudoalteromonas.7491 - part.12 part:PARC_a0304 hsdR; type I restriction enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.235218 Gammaproteobacteria.186822 Pseudoalteromonas.7491 - png.3885 png:PNIG_p0065 hsdR; type I restriction enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.235218 Gammaproteobacteria.434648 - - mpsy.3410 mpsy:CEK71_18125 deoxyribonuclease HsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.235218 Other_proteobacteria.7905 Mariprofundus.2300 - maes.2176 maes:Ga0123461_2248 type I restriction enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.235219 Gammaproteobacteria.388910 Vibrio.28274 - vhr.2613 vhr:AL538_13970 deoxyribonuclease HsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.291852 Gammaproteobacteria.246421 Francisella.4016 Francisella_philomiragia.3026 fpz.1261 fpz:LA55_276 putative type I restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.291852 Epsilonproteobacteria.2253 - - wsu.1035 wsu:WS1129 HSDR; HSDR PROTEIN PROBABLE TYPE I RESTRICTION ENZYME RESTRICTIONCHAIN; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.291852 Epsilonproteobacteria.2253 Sulfurimonas.1826 - sua.1334 sua:Saut_1342 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.291852 Epsilonproteobacteria.2253 Aliiarcobacter.2128 - abl.876 abl:A7H1H_0910 type I restriction-modification system, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.291852 Epsilonproteobacteria.2253 - - alp.983 alp:LPB137_05100 deoxyribonuclease HsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Proteobacteria.291852 Epsilonproteobacteria.2253 Sulfurospirillum.4751 - smul.2712 smul:SMUL_2827 type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49788 Sphingobacterium.11167 - - smiz.1725 smiz:4412673_01759 hsdR; Type-1 restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49788 Cyclobacterium.5338 - - cmr.3219 cmr:Cycma_3305 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49788 Echinicola.5437 - - evi.4175 evi:Echvi_4436 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49788 Rufibacter.3307 Rufibacter_sp_.2231 - rud.1523 rud:TH61_08545 deoxyribonuclease HsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49788 - - - flm.3959 flm:MY04_4082 hsdR; Type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49788 Lutibacter.4612 - - lut.2288 lut:Lupro_11895 deoxyribonuclease HsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Bacteria.307954 Bacteroidetes.49792 Fibrella.4518 - - fae.3366 fae:FAES_3371 hsdR; type I restriction enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.22694 Euryarchaeota.24439 Methanosphaera.840 - - mst.470 mst:Msp_0477 putative type I restriction-modification system, restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.22694 Euryarchaeota.24439 Methanosphaera.840 - - metb.346 metb:AW729_01595 restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.22694 Euryarchaeota.24439 Methanobrevibacter.2696 Methanobrevibacter_sp_.623 - meb.510 meb:Abm4_0518 hsdR2; type I restriction-modification system R subunit HsdR2; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.22694 Euryarchaeota.24439 Methanobacterium.1573 Methanobacterium_sp_.554 - meth.473 meth:MBMB1_0472 hsdR; Type-1 restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.22694 Euryarchaeota.24439 Methanobacterium.1573 Methanobacterium_formicicum.2118 - mfc.279 mfc:BRM9_0280 hsdR; type I restriction-modification system R subunit HsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.65412 Euryarchaeota.50445 Methanococcoides.2059 - - mbu.1633 mbu:Mbur_1841 type-1 site specific restriction enzyme R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.65956 Euryarchaeota.51000 Methanococcus.3676 - - mvn.99 mvn:Mevan_0082 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.66058 Euryarchaeota.51103 Methanococcus.3870 - - mvo.275 mvo:Mvol_0317 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185835 Archaea.90139 Euryarchaeota.76450 - - - tar.804 tar:TALC_00821 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185836 Archaea.73863 Euryarchaeota.59086 Methanosphaera.1927 - - mst.449 mst:Msp_0454 partially conserved hypothetical protein OC.185837 Eukaryotes.426761 Protists.63444 Stramenopiles.7830 Oomycetes.10350 - pif.6390 pif:PITG_06656 hypothetical protein OC.185837 Eukaryotes.426761 Protists.63444 Stramenopiles.7830 Oomycetes.10350 - psoj.15520 psoj:PHYSODRAFT_522445 hypothetical protein OC.185837 Eukaryotes.426761 Protists.63444 Stramenopiles.7830 Oomycetes.10350 - spar.475 spar:SPRG_21305 hypothetical protein OC.185837 Eukaryotes.426761 Protists.63444 Stramenopiles.7830 Oomycetes.10350 - spar.475 spar:SPRG_00185 hypothetical protein OC.185838 Archaea.71503 Euryarchaeota.56697 Methanosarcina.8183 Methanosarcina_siciliae.4186 - msj.2319 msj:MSSAC_2407 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185839 Archaea.64272 Euryarchaeota.49268 Methanocella.2383 - - mez.378 mez:Mtc_0336 hypothetical protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185840 Archaea.95838 Thaumarchaeota.10058 - - - ndv.631 ndv:NDEV_0579 Helicase, type I site-specific restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185841 Archaea.29863 Euryarchaeota.33726 Methanosarcina.4142 Methanosarcina_sp_.6514 - mek.3384 mek:MSKOL_3415 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185841 Archaea.29863 Euryarchaeota.33726 Methanosarcina.4142 Methanosarcina_barkeri.6 - mba.1001 mba:Mbar_A1014 type I restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185841 Archaea.29863 Euryarchaeota.33726 Methanosarcina.4142 Methanosarcina_barkeri.6 - mbw.3669 mbw:MSBRW_3705 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185841 Archaea.29863 Euryarchaeota.33726 Methanosarcina.7855 Methanosarcina_mazei.4408 - mmj.568 mmj:MSMAS_0549 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185841 Archaea.29863 Euryarchaeota.33726 - - - mev.521 mev:Metev_0465 protein of unknown function DUF450; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185842 Archaea.66137 Euryarchaeota.51182 Methanococcus.3994 - - mvo.457 mvo:Mvol_0516 type III restriction protein res subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185843 Archaea.65573 Euryarchaeota.50611 Methanococcus.971 Methanococcus_maripaludis.2079 - mmq.639 mmq:MmarC5_0639 type III restriction enzyme, res subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185843 Archaea.65573 Euryarchaeota.50611 Methanococcus.971 - - mvn.268 mvn:Mevan_0265 type III restriction protein res subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185844 Archaea.20197 Euryarchaeota.20904 Halobacterium.3347 - - hdl.173 hdl:HALDL1_00805 type I restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185844 Archaea.20197 Euryarchaeota.20904 - - - hru.2677 hru:Halru_2805 type I restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185844 Archaea.20197 Euryarchaeota.20904 - - - naj.1167 naj:B1756_05925 restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185845 Archaea.86201 Euryarchaeota.72332 - - - mla.847 mla:Mlab_0843 protein of unknown function DUF450; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185846 Archaea.30036 Euryarchaeota.33906 Methanosarcina.4693 Methanosarcina_mazei.1963 - mma.2915 mma:MM_2976 type I restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185846 Archaea.30036 Euryarchaeota.33906 Methanosarcina.4693 Methanosarcina_mazei.1963 - mmj.1672 mmj:MSMAS_1705 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185846 Archaea.30036 Euryarchaeota.33906 Methanosarcina.4693 - - mvc.2722 mvc:MSVAZ_2755 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185846 Archaea.30036 Euryarchaeota.33906 - - - mhz.629 mhz:Metho_0639 helicase, type I site-specific restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185847 Archaea.69274 Euryarchaeota.54429 Methanosaeta.3238 - - mhi.1751 mhi:Mhar_1856 Type I site-specific deoxyribonuclease chain R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanococcus.2107 Methanococcus_maripaludis.1892 - mmd.627 mmd:GYY_03170 type I restriction-modification enzyme, subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanothermobacter.2041 - - mmg.1437 mmg:MTBMA_c14690 hsdR2; predicted type I restriction-modification enzyme, subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanothermobacter.2279 - - mwo.1267 mwo:MWSIV6_1290 putative type-1 restriction enzyme MjaXP R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanobrevibacter.2614 Methanobrevibacter_sp_.242 - meb.111 meb:Abm4_0077 hsdR1; type I restriction-modification system R subunit HsdR1; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanobacterium.1787 Methanobacterium_sp_.2645 - metn.684 metn:BK008_03555 restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanobacterium.1787 Methanobacterium_formicicum.2463 - mfi.994 mfi:DSM1535_1020 hsdR2; type I restriction-modification enzyme, subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185848 Archaea.22833 Euryarchaeota.24654 Methanobacterium.1787 - - msub.1511 msub:BK009_07900 restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Dictyostelium.1298 - ddi.10663 ddi:DDB_G0295679 helicase superfamily 1 and 2 domain-containing protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Dictyostelium.1298 - dpp.1945 dpp:DICPUDRAFT_150026 hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Dictyostelium.8078 - ddi.9925 ddi:DDB_G0292234 hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Dictyostelium.8078 - dpp.10017 dpp:DICPUDRAFT_99404 hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 - - dfa.1804 dfa:DFA_00968 hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 - - dfa.6826 dfa:DFA_08295 helicase domain-containing protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Entamoeba.3225 - ehi.2054 ehi:EHI_046680 213.t00003; hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Entamoeba.3225 - edi.3205 edi:EDI_124010 hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 Entamoeba.3225 - eiv.7865 eiv:EIN_410300 hypothetical protein OC.185849 Eukaryotes.412622 Protists.31105 Amoebozoa.1273 - - acan.9656 acan:ACA1_289870 DEAD/DEAH box helicase OC.185850 Archaea.72450 Euryarchaeota.57657 Methanosarcina.9540 Methanosarcina_thermophila.2573 - mthr.1047 mthr:MSTHT_1047 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185851 Archaea.1329 Euryarchaeota.8456 Ferroplasma.1762 - - fac.1388 fac:FACI_IFERC01G1416 hypothetical protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_barkeri.1702 - mba.2556 mba:Mbar_A2662 putative type I restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_barkeri.1702 - mbw.2054 mbw:MSBRW_2065 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_mazei.1730 - mma.2682 mma:MM_2733 hypothetical protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_mazei.1730 - mmj.1924 mmj:MSMAS_1977 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_mazei.1730 - mmac.1148 mmac:MSMAC_1143 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 - - mls.1746 mls:MSLAZ_1815 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_siciliae.1315 - msj.2516 msj:MSSAC_2632 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_siciliae.1315 - msw.2199 msw:MSSIT_2211 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185852 Archaea.29148 Euryarchaeota.32990 Methanosarcina.1295 Methanosarcina_siciliae.4816 - msz.2205 msz:MSSIH_2217 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Methanothermobacter.19 Methanothermobacter_sp_.1004 - metc.849 metc:MTCT_0854 type I restriction modification system subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Methanothermobacter.19 Methanothermobacter_sp_.1004 - mete.894 mete:tca_00903 hsdR; Type-1 restriction enzyme R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Methanothermobacter.19 - - mth.1804 mth:MTH_940 type I restriction enzyme; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Methanothermobacter.19 - - mmg.1303 mmg:MTBMA_c13260 hsdR1; predicted type I restriction-modification enzyme, subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Archaeoglobus.1208 Archaeoglobus_fulgidus.757 - afu.1671 afu:AF_1708 type I restriction-modification enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Archaeoglobus.1208 Archaeoglobus_fulgidus.757 - afg.1840 afg:AFULGI_00019570 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Archaeoglobus.1208 - - ave.1796 ave:Arcve_1898 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Archaeoglobus.1208 - - ast.1146 ast:Asulf_01170 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Geoglobus.2503 - - gah.1294 gah:GAH_01365 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 - - - pto.85 pto:PTO0076 type I restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Thermococcus.5334 Thermococcus_sp_.38 - the.229 the:GQS_01145 Type I restriction-modification system restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Thermococcus.5334 Thermococcus_sp_.38 - tha.571 tha:TAM4_1568 Type I restriction-modification system restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Thermococcus.5334 - - tba.1587 tba:TERMP_01589 Type I restriction-modification system restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Thermococcus.5334 - - tgg.1262 tgg:A3K92_06580 restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 - - - ppac.1014 ppac:PAP_05225 restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.8455 Methanoculleus.3343 - - mema.1237 mema:MMAB1_1251 Type I restriction enzyme; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Euryarchaeota.63436 Thermococcus.12609 - - tpep.1198 tpep:A0127_06290 hypothetical protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185853 Archaea.1327 Crenarchaeota.17097 Staphylothermus.1731 - - smr.750 smr:Smar_0763 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185854 Archaea.65192 Euryarchaeota.50216 Methanocella.3853 - - rci.2509 rci:RCIX971 hsdR-1; type I restriction modification enzyme,restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185855 Archaea.63648 Euryarchaeota.48602 Methanocaldococcus.1889 - - mja.1741 mja:MJ_ECL40 type I restriction enzyme; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185855 Archaea.63648 Euryarchaeota.48602 Methanocaldococcus.1889 - - mvu.916 mvu:Metvu_0933 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185856 Archaea.86447 Euryarchaeota.72585 - - - mok.1332 mok:Metok_1378 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185857 Archaea.30471 Euryarchaeota.34359 Methanosarcina.5670 Methanosarcina_sp_.5920 - mek.2768 mek:MSKOL_2786 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185857 Archaea.30471 Euryarchaeota.34359 Methanosarcina.5670 Methanosarcina_sp_.7973 - metm.1197 metm:MSMTP_1184 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185857 Archaea.30471 Euryarchaeota.34359 Methanosarcina.5670 Methanosarcina_siciliae.4476 - msw.1063 msw:MSSIT_1046 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185857 Archaea.30471 Euryarchaeota.34359 Methanosarcina.5670 Methanosarcina_thermophila.1320 - mthe.2255 mthe:MSTHC_2258 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185857 Archaea.30471 Euryarchaeota.34359 Methanosarcina.5670 Methanosarcina_thermophila.1320 - mthr.1048 mthr:MSTHT_1048 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185858 Eukaryotes.708080 Plants.197265 Eudicots.246105 Spurge_family.27126 - rcu.8842 rcu:8270086 uncharacterized protein LOC8270086 OC.185859 Archaea.88088 Euryarchaeota.74259 - - - mzh.1353 mzh:Mzhil_1435 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185860 Archaea.85007 Euryarchaeota.70990 - - - mhu.2432 mhu:Mhun_2781 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185861 Archaea.30080 Euryarchaeota.33953 Methanosarcina.4825 Methanosarcina_sp_.8124 - metm.1364 metm:MSMTP_1353 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185861 Archaea.30080 Euryarchaeota.33953 Methanosarcina.4825 Methanosarcina_mazei.2474 - mma.460 mma:MM_0431 type I restriction-modification system restriction subnit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185861 Archaea.30080 Euryarchaeota.33953 Methanosarcina.4825 Methanosarcina_mazei.2474 - mmj.886 mmj:MSMAS_0872 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185861 Archaea.30080 Euryarchaeota.33953 Methanosarcina.4825 Methanosarcina_mazei.2474 - mmac.887 mmac:MSMAC_0861 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185861 Archaea.30080 Euryarchaeota.33953 Methanosarcina.4825 - - mvc.2139 mvc:MSVAZ_2160 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185862 Archaea.27335 Euryarchaeota.30618 Methanococcus.681 Methanococcus_maripaludis.1606 - mmx.49 mmx:MmarC6_0040 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185862 Archaea.27335 Euryarchaeota.30618 Methanococcus.681 Methanococcus_maripaludis.1606 - mmz.28 mmz:MmarC7_0017 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185862 Archaea.27335 Euryarchaeota.30618 Methanococcus.681 Methanococcus_maripaludis.1606 - mmd.872 mmd:GYY_04440 HsdR family type I site-specific deoxyribonuclease; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185863 Archaea.71452 Euryarchaeota.56645 Methanosarcina.8114 Methanosarcina_siciliae.3988 - msj.1549 msj:MSSAC_1572 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185864 Archaea.93378 Thaumarchaeota.6590 Nitrososphaera.4295 - - nga.2696 nga:Ngar_c29150 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 Methanosarcina.4579 Methanosarcina_mazei.1210 - mma.2176 mma:MM_2204 hypothetical protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 Methanosarcina.4579 Methanosarcina_mazei.1210 - mmaz.2112 mmaz:MmTuc01_2253 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 Methanosarcina.4579 Methanosarcina_mazei.1210 - mmac.1912 mmac:MSMAC_1955 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 Methanosarcina.4579 Methanosarcina_siciliae.4123 - msj.2062 msj:MSSAC_2137 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 Methanosarcina.4579 - - mhor.3041 mhor:MSHOH_3124 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 Methanococcoides.1905 - - mbu.1063 mbu:Mbur_1213 type I restriction endonuclease; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185865 Archaea.26665 Euryarchaeota.29730 - - - mhz.1245 mhz:Metho_1322 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185866 Archaea.86761 Euryarchaeota.72905 - - - mpi.1583 mpi:Mpet_1680 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185867 Archaea.68448 Euryarchaeota.53567 Methanosaeta.1747 - - mcj.230 mcj:MCON_0084 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185868 Archaea.65455 Euryarchaeota.50489 Methanococcoides.2253 - - mmet.480 mmet:MCMEM_0453 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 Methanosarcina_sp_.4200 - mek.990 mek:MSKOL_0981 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 Methanosarcina_mazei.3386 - mma.2261 mma:MM_2292 type I restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 - - mvc.1022 mvc:MSVAZ_1009 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 Methanosarcina_siciliae.54 - msj.1081 msj:MSSAC_1047 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 Methanosarcina_siciliae.54 - msz.917 msz:MSSIH_0909 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 Methanosarcina_siciliae.54 - msw.959 msw:MSSIT_0941 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 Methanosarcina.4966 - - mhor.1089 mhor:MSHOH_1066 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185869 Archaea.30149 Euryarchaeota.34022 - - - mhz.1282 mhz:Metho_1370 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185870 Archaea.87790 Euryarchaeota.73952 - - - mpy.2114 mpy:Mpsy_2239 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185871 Archaea.65746 Euryarchaeota.50786 Methanococcus.2222 Methanococcus_maripaludis.2066 - mmq.619 mmq:MmarC5_0616 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185872 Archaea.71301 Euryarchaeota.56493 Methanosarcina.7909 Methanosarcina_mazei.4512 - mmj.2429 mmj:MSMAS_2495 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185873 Archaea.90940 Thaumarchaeota.2306 Nitrosopumilus.4110 - - nmr.612 nmr:Nmar_0608 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185873 Archaea.90940 Thaumarchaeota.2306 Nitrososphaera.4790 - - nvn.2118 nvn:NVIE_022180 putative Type I restriction-modification system, restriction subunit R, site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185874 Archaea.60204 Euryarchaeota.45109 Haloquadratum.2740 - - hwc.1865 hwc:Hqrw_3308 hsdR; type I site-specific deoxyribonuclease subunit hsdR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185875 Archaea.51924 Euryarchaeota.21269 Halobacterium.4587 - - hdl.3199 hdl:HALDL1_16615 type I restriction endonuclease subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185875 Archaea.51924 Euryarchaeota.21269 Halorhabdus.2209 - - hti.586 hti:HTIA_0560 type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185876 Archaea.52847 Euryarchaeota.26031 Methanobacterium.4001 - - mcub.1354 mcub:MCBB_1415 putative type-1 restriction enzyme MjaXP R protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185876 Archaea.52847 Euryarchaeota.26031 - - - mpl.1052 mpl:Mpal_1092 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185877 Archaea.71944 Euryarchaeota.57145 Methanosarcina.8750 Methanosarcina_sp_.5609 - mek.2448 mek:MSKOL_2462 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185878 Archaea.28328 Euryarchaeota.31915 Methanosarcina.6400 Methanosarcina_barkeri.4087 - mby.2339 mby:MSBRM_2385 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185878 Archaea.28328 Euryarchaeota.31915 Methanosarcina.6400 Methanosarcina_barkeri.4087 - mbar.2334 mbar:MSBR2_2351 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185878 Archaea.28328 Euryarchaeota.31915 Methanohalophilus.2093 - - mmh.1021 mmh:Mmah_1045 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185878 Archaea.28328 - - - - arg.212 arg:QT11_C0001G0204 Type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 Halobacterium.2699 Halobacterium_salinarum.1412 - hal.235 hal:VNG_0108G rmeR; type I restriction modification enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 Halobacterium.2699 Halobacterium_salinarum.1412 - hsl.199 hsl:OE_1178F rmeR; type I site-specific deoxyribonuclease subunit RmeR OC.185879 Archaea.20086 Euryarchaeota.20759 Halorhabdus.2981 - - hut.127 hut:Huta_0101 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 - - - hali.3490 hali:BV210_18535 DEAD/DEAH box helicase; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 - - - harc.393 harc:HARCEL1_01810 DEAD/DEAH box helicase; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 Haloquadratum.2254 - - hwc.18 hwc:Hqrw_2618 rmeR1; type I site-specific deoxyribonuclease subunit RmeR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 Haloquadratum.2254 - - hwc.18 hwc:Hqrw_5070 rmeR2; type I site-specific deoxyribonuclease subunit RmeR; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 - - - hru.1881 hru:Halru_1967 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185879 Archaea.20086 Euryarchaeota.20759 - - - naj.3225 naj:B1756_17045 DEAD/DEAH box helicase; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185880 Archaea.71510 Euryarchaeota.56705 Methanosarcina.8193 Methanosarcina_siciliae.4221 - msj.2515 msj:MSSAC_2631 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185881 Eukaryotes.464736 Animals.230832 Arthropods.94136 Insects.110862 - nvi.11335 nvi:107981567 putative type I restriction enzyme HindVIIP R protein OC.185882 Archaea.1328 Euryarchaeota.27593 Methanocaldococcus.1969 - - mfe.752 mfe:Mefer_0776 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 Methanocaldococcus.2433 - - mja.131 mja:MJ_0124 type I restriction-modification enzyme 2, R subunit OC.185882 Archaea.1328 Euryarchaeota.27593 Methanocaldococcus.2519 - - mja.1232 mja:MJ_1214 type I restriction-modification enzyme 1, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 - - - mig.723 mig:Metig_0752 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 - - - fpl.2091 fpl:Ferp_2194 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 Pyrococcus.5246 - - pab.1489 pab:PAB2154 hsdR type I restriction-modification enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 Thermococcus.7812 - - ths.1562 ths:TES1_1585 type I restriction-modification enzyme, R subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 Thermococcus.7812 - - tnu.1167 tnu:BD01_1187 Type I site-specific restriction-modification system, R (restriction) subunit-related helicase; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Euryarchaeota.27593 Thermococcus.7812 - - tce.1435 tce:A3L02_07600 hypothetical protein; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185882 Archaea.1328 Crenarchaeota.17601 Sulfolobus.6070 Sulfolobus_islandicus.4120 - sih.1403 sih:SiH_1435 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185883 Archaea.75189 Euryarchaeota.60435 Natronolimnobius.972 - - nag.1952 nag:AArcMg_1979 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185883 Archaea.75189 Euryarchaeota.60435 Natronolimnobius.972 - - nan.1673 nan:AArc1_1695 Type I site-specific restriction-modification system, R (restriction) subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185884 Eukaryotes.544461 Animals.341856 - - - aqu.12813 aqu:109591136 uncharacterized protein LOC109591136 OC.185885 Archaea.30584 Euryarchaeota.34480 Methanosarcina.5953 Methanosarcina_sp_.468 - mef.1433 mef:MSWH1_1462 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185885 Archaea.30584 Euryarchaeota.34480 Methanosarcina.5953 Methanosarcina_sp_.468 - meq.1826 meq:MSWHS_1868 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185885 Archaea.30584 Euryarchaeota.34480 Methanosarcina.5953 - - mls.1710 mls:MSLAZ_1778 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185885 Archaea.30584 Euryarchaeota.34480 Methanosarcina.8104 Methanosarcina_siciliae.3954 - msj.1338 msj:MSSAC_1341 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185885 Archaea.30584 Euryarchaeota.34480 - - - mpy.637 mpy:Mpsy_0636 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185885 Archaea.30584 Euryarchaeota.34481 Methanosarcina.8103 Methanosarcina_siciliae.3953 - msj.1337 msj:MSSAC_1340 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185886 Archaea.72712 Euryarchaeota.57920 Methanosarcina.9858 - - mac.2321 mac:MA_2451 hypothetical protein OC.185887 Archaea.70406 Euryarchaeota.55594 Methanosarcina.6871 Methanosarcina_barkeri.6816 - mbar.2333 mbar:MSBR2_2350 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185888 Archaea.1326 Bathyarchaeota.1509 - - - barb.1282 barb:AOA66_1344 Type III restriction enzyme, res subunit; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185889 Archaea.70241 Euryarchaeota.55429 Methanosarcina.6656 Methanosarcina_barkeri.5356 - mbak.897 mbak:MSBR3_0873 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3] OC.185890 Archaea.71595 Euryarchaeota.56792 Methanosarcina.8309 Methanosarcina_siciliae.4556 - msw.2200 msw:MSSIT_2212 Type I restriction-modification system, restriction subunit R; K01153 type I restriction enzyme, R subunit [EC:3.1.21.3]