# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.187895 Bacteria.370470 Tenericutes.17081 Spiroplasma.4324 - - sck.1276 sck:SCITRI_00820 hsdM; putative Type I restriction-modification system, methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187896 Bacteria.436269 Cyanobacteria.29482 Leptolyngbya.12380 Leptolyngbya_sp_.12472 - let.2268 let:O77CONTIG1_02329 putative type I restriction enzymeP M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187896 Bacteria.436269 Cyanobacteria.29482 Nostoc.19993 Nostoc_sp_.17470 - nos.3435 nos:Nos7107_3604 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187896 Bacteria.436269 Cyanobacteria.29482 Nostoc.26336 - - npu.4874 npu:Npun_R3329 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.317357 Gammaproteobacteria.153810 Vibrio.22265 Vibrio_parahaemolyticus.6383 vph.1171 vph:VPUCM_1161 Type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.317357 Gammaproteobacteria.153810 Shewanella.17816 - son.1255 son:SO_1457 type II restriction-modification system methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.317357 Gammaproteobacteria.153810 Glaciecola.5692 - gni.1237 gni:GNIT_1270 type I restriction-modification system, M subunit, putative; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.317357 Gammaproteobacteria.153810 Salinimonas.2837 - salh.2799 salh:HMF8227_02875 hsdM; Site-specific DNA-methyltransferase (adenine-specific); K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.317357 Gammaproteobacteria.153810 Thalassolituus.3042 - tol.211 tol:TOL_0188 type I restriction-modification system, M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.513422 Betaproteobacteria.189513 Massilia.12790 - mass.1353 mass:CR152_06535 restriction endonuclease subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Proteobacteria.772512 Gammaproteobacteria.418444 - - gpb.2821 gpb:HDN1F_29050 Type I restriction-modification system, methyltransferase subunit OC.187897 Bacteria.381042 Proteobacteria.772513 Gammaproteobacteria.418445 - - gpb.2822 gpb:HDN1F_29060 Type I restriction-modification system, methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Actinobacteria.241236 Streptomyces.79349 Streptomyces_sp_.9077 - scx.3146 scx:AS200_16775 restriction endonuclease subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Actinobacteria.255365 Streptomyces.110753 - - ssia.3960 ssia:A7J05_20785 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Cyanobacteria.14738 Anabaena.4310 Anabaena_sp_.3916 - anb.2859 anb:ANA_C13003 N6 adenine-specific DNA methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187897 Bacteria.381042 Cyanobacteria.14738 - - - riv.4671 riv:Riv7116_4991 type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187898 Bacteria.1013042 Proteobacteria.454644 Alphaproteobacteria.307894 - - cij.2531 cij:WG74_13320 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187899 Bacteria.398456 Proteobacteria.631113 Epsilonproteobacteria.17107 Helicobacter.6093 Helicobacter_cetorum.2446 hcm.1435 hcm:HCD_07780 type I restriction/modification system N-6 DNA methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187900 Bacteria.398453 Cyanobacteria.37729 Anabaena.4786 Anabaena_sp_.4485 - awa.417 awa:AA650_01770 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187900 Bacteria.398454 - - - - mib.904 mib:UY43_C0001G0963 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187900 Bacteria.398457 Proteobacteria.494399 Betaproteobacteria.155450 Burkholderia.46751 Burkholderia_pseudomallei.11672 bpsm.5251 bpsm:BBQ_5808 N-6 DNA Methylase family protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187900 Bacteria.398457 Proteobacteria.494399 Betaproteobacteria.155450 Burkholderia.46751 Burkholderia_pseudomallei.11672 bpsu.3030 bpsu:BBN_3788 N-6 DNA Methylase family protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187900 Bacteria.398458 Proteobacteria.663604 Gammaproteobacteria.246375 Francisella.3959 Francisella_philomiragia.2829 fpz.593 fpz:LA55_1535 N-6 DNA Methylase family protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187901 Bacteria.398455 Aquificae.5432 Thermocrinis.1726 - - trd.384 trd:THERU_01920 type I restriction-modification protein subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187902 Bacteria.398452 Bacteroidetes.129095 Spirosoma.10856 - - srd.338 srd:SD10_01640 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187903 Bacteria.1238858 Spirochaetes.14708 Brachyspira.3704 - - brm.957 brm:Bmur_0921 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.172308 Betaproteobacteria.205967 Paraburkholderia.24822 - bcai.8277 bcai:K788_0008013 Type I restriction-modification enzyme M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.172308 Alphaproteobacteria.294547 Sphingorhabdus.4508 - sfla.1567 sfla:SPHFLASMR4Y_01614 hsdM; type I restriction enzyme EcoKI M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.172308 Alphaproteobacteria.299412 Zymomonas.2156 - zmo.1649 zmo:ZMO1934 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Helicobacter.8634 - had.842 had:CDV25_04715 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_jejuni.2063 cjd.569 cjd:JJD26997_0689 dna methylase-type I restriction-modification system; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_jejuni.2064 cju.983 cju:C8J_0988 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_jejuni.2064 cjm.983 cjm:CJM1_1026 hsdM4; Type I Restriction Enzyme; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_jejuni.2064 cjv.995 cjv:MTVDSCj20_1053 type I restriction/modification system, restriction/methyltransferase domains; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_jejuni.2064 cjx.1032 cjx:BN867_10400 Type I restriction-modification enzyme M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_coli.2465 ccf.712 ccf:YSQ_03765 type I restriction-modification protein subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.2656 Campylobacter_subantarcticus.1850 csm.1221 csm:CSUB8521_1320 type I restriction/modification system, M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.293877 Epsilonproteobacteria.5364 Campylobacter.8629 - cavi.1325 cavi:CAV_1421 type I restriction/modification system, M subunit (HsdR N-terminal domain); K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mht.1950 mht:D648_6080 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhq.1118 mhq:D650_21510 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhat.1917 mhat:B824_6580 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhx.1140 mhx:MHH_c12110 putative HsdM-like methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhae.2116 mhae:F382_11165 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mham.1853 mham:J450_09810 type I restriction endonuclease subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhao.2100 mhao:J451_11275 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhal.657 mhal:N220_03280 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhaq.1987 mhaq:WC39_10585 type I restriction-modification protein subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Mannheimia.275 Mannheimia_haemolytica.1248 mhay.1984 mhay:VK67_10585 type I restriction-modification protein subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.322541 Gammaproteobacteria.172719 Moraxella.3225 - mboi.481 mboi:DQF64_02150 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.553096 Deltaproteobacteria.17915 Geobacter.13018 - gur.3384 gur:Gura_3600 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.553096 Deltaproteobacteria.17915 Desulfobulbus.3808 - dpr.2322 dpr:Despr_2450 protein of unknown function DUF450; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.575835 Deltaproteobacteria.78896 Geobacter.8910 - gbm.3160 gbm:Gbem_3247 type I restriction-modification system, DNA adenine N6-methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.638705 Epsilonproteobacteria.27193 - - wsu.1478 wsu:WS1649 DNA METHYLASE-TYPE I RESTRICTION-MODIFICATION SYSTEM; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Proteobacteria.768774 Gammaproteobacteria.408268 - - ebh.741 ebh:BSEPE_0784 type I restriction enzyme, M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Firmicutes.254971 Firmicutes___Clostridia.114562 Clostridium.50582 - ctae.518 ctae:BGI42_02785 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Cyanobacteria.17441 Synechococcus.13258 Synechococcus_sp_.11348 - syne.1231 syne:Syn6312_1254 type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Cyanobacteria.17441 Synechococcus.16659 Synechococcus_sp_.14969 - synp.973 synp:Syn7502_00979 type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Cyanobacteria.17441 Synechococcus.22471 Synechococcus_sp_.20794 - syp.2979 syp:SYNPCC7002_F0089 Type I restriction modification system, N-6 DNA Methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Cyanobacteria.17441 Geminocystis.3527 - - gee.3311 gee:GM3708_777 type I restriction-modification enzyme M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Cyanobacteria.17441 Anabaena.6929 - - acy.1631 acy:Anacy_1751 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Spirochaetes.25214 Treponema.5055 - - tpi.3147 tpi:TREPR_3692 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Spirochaetes.25214 Treponema.5055 - - tped.714 tped:TPE_0701 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Spirochaetes.31187 Treponema.12006 - - trm.978 trm:JO41_05485 type I restriction-modification protein subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Bacteroidetes.57163 - - - als.148 als:DJ013_00325 SAM-dependent methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Bacteroidetes.57163 Chryseobacterium.11161 - - ctak.2125 ctak:4412677_02232 hsdM; Type I restriction enzyme EcoKI M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187904 Bacteria.398451 Bacteroidetes.118064 Porphyromonas.2049 Porphyromonas_gingivalis.1887 - pgi.479 pgi:PG_0544 type I restriction-modification system, M subunit, putative; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187905 Bacteria.185962 Proteobacteria.227622 Gammaproteobacteria.384688 Vibrio.19864 Vibrio_cholerae.5194 vcz.526 vcz:VAB027_1480 N-6 DNA Methylase family protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187905 Bacteria.185962 Proteobacteria.227622 Betaproteobacteria.166314 Burkholderia.84462 - bur.32 bur:Bcep18194_A3192 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187906 Bacteria.1038099 Proteobacteria.493968 Betaproteobacteria.154954 Burkholderia.46162 Burkholderia_pseudomallei.3447 bps.3081 bps:BPSL3118 restriction modification system methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187906 Bacteria.1038099 Proteobacteria.493968 Betaproteobacteria.154954 Burkholderia.46162 Burkholderia_pseudomallei.3447 bpd.3588 bpd:BURPS668_3644 putative type I restriction-modification system, M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187907 Bacteria.185821 Actinobacteria.175191 Bifidobacterium.7545 Bifidobacterium_breve.2985 - bbrn.858 bbrn:B2258_0917 N-6 DNA Methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187907 Bacteria.185821 Actinobacteria.203447 Mycobacterium.22088 Mycobacterium_intracellulare.6371 - mia.4686 mia:OCU_47110 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187907 Bacteria.185821 Cyanobacteria.50684 Microcystis.5221 - - mar.3515 mar:MAE_39860 type I restriction enzyme EcoEI M protein OC.187908 Bacteria.645782 Actinobacteria.218231 Olsenella.1466 - - olo.730 olo:ADJ70_04280 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187909 Bacteria.381044 Actinobacteria.273586 - - - dva.597 dva:DAD186_06170 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187910 Bacteria.185984 Proteobacteria.302902 Gammaproteobacteria.121889 Gammaproteobacteria___Enterobacteria.109302 - hde.1296 hde:HDEF_1592 putative restriction endonuclease, N6_Mtase domain protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187910 Bacteria.185984 Proteobacteria.302902 Gammaproteobacteria.121889 Xanthomonas.10533 Xanthomonas_campestris.4221 xcc.4017 xcc:XCC4142 XmnI methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187910 Bacteria.185984 Proteobacteria.302902 Gammaproteobacteria.121889 Xanthomonas.10533 Xanthomonas_campestris.4221 xcb.4131 xcb:XC_4234 XmnI methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187910 Bacteria.185984 Proteobacteria.427888 Alphaproteobacteria.268142 Rickettsia.3481 Rickettsia_canadensis.779 rcm.910 rcm:A1E_04720 ligA; NAD-dependent DNA ligase LigA; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187910 Bacteria.185984 Proteobacteria.427888 Alphaproteobacteria.268142 Rickettsia.3481 Rickettsia_canadensis.779 rcc.842 rcc:RCA_04360 NAD-dependent DNA ligase LigA; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187910 Bacteria.185984 Bacteroidetes.104015 Gramella.3463 - - gfl.1120 gfl:GRFL_1114 Type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187911 Bacteria.443475 Proteobacteria.575821 Deltaproteobacteria.78878 Geobacter.8887 - gbm.2921 gbm:Gbem_2995 type I restriction-modification system, DNA adenine N6-methyltransferase subunit OC.187911 Bacteria.443475 Deinococcus_Thermus.13993 Deinococcus.11593 - - dwu.2755 dwu:DVJ83_16405 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187912 Bacteria.461322 Proteobacteria.493400 Betaproteobacteria.154125 Burkholderia.44934 Burkholderia_multivorans.6454 bmk.1426 bmk:DM80_2310 methyltransferase small domain protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187912 Bacteria.461322 Proteobacteria.706184 Gammaproteobacteria.304216 Histophilus.1936 - hsm.1813 hsm:HSM_1880 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187912 Bacteria.461322 Firmicutes.291252 Firmicutes___Clostridia.165413 - - fpla.3341 fpla:A4U99_18235 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187912 Bacteria.461322 Tenericutes.11162 Entomoplasma.1444 - - eml.242 eml:EMELA_v1c02490 hsdM; type I restriction enzyme M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187913 Bacteria.336618 Firmicutes.235959 Firmicutes___Clostridia.81016 Ruminococcus.9907 - rus.367 rus:RBI_I00362 Site-specific DNA-methyltransferase (adenine-specific); K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187913 Bacteria.336618 Firmicutes.235959 Firmicutes___Clostridia.81016 - - adg.770 adg:Adeg_0823 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187913 Bacteria.336618 Actinobacteria.113022 Bifidobacterium.7211 Bifidobacterium_bifidum.2009 - bbi.1193 bbi:BBIF_1197 putative N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187913 Bacteria.336618 Actinobacteria.113022 - - - pdo.1428 pdo:PSDT_1465 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Proteobacteria.287498 Epsilonproteobacteria.20927 Helicobacter.11866 - hty.1346 hty:BN2458_PEG1376 type II restriction-modification enzyme; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Proteobacteria.287498 Deltaproteobacteria.75982 Desulfuromonas.3355 - des.3197 des:DSOUD_3343 type I restriction-modification system, DNA methylase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Firmicutes.243871 Firmicutes___Clostridia.97320 Caldicellulosiruptor.3159 - chd.352 chd:Calhy_0371 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Firmicutes.247597 Firmicutes___Clostridia.103110 Clostridium.28605 Clostridium_kluyveri.1820 ckl.2789 ckl:CKL_2938 Type I methyltransferase subunit-related protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Firmicutes.247597 Firmicutes___Clostridia.103110 Clostridium.28605 Clostridium_kluyveri.1820 ckr.2585 ckr:CKR_2604 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Tenericutes.19790 - - - mbj.1314 mbj:KQ51_01372 putative type I restriction enzymeP M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Cyanobacteria.41808 Cyanothece.8300 - - cyc.1082 cyc:PCC7424_0972 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Spirochaetes.13858 Brachyspira.2841 Brachyspira_hyodysenteriae.2607 - bhy.405 bhy:BHWA1_00405 type II restriction-modification enzyme; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187914 Bacteria.184991 Deferribacteres.5000 - - - fsi.1607 fsi:Flexsi_1784 type II restriction-modification enzyme; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.129182 Alphaproteobacteria.159259 Rickettsia.2335 Rickettsia_bellii.391 rbe.1378 rbe:RBE_1419 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.129182 Alphaproteobacteria.159259 Rickettsia.2335 Rickettsia_bellii.391 rbo.1417 rbo:A1I_07890 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.129182 Alphaproteobacteria.159259 Rickettsia.2335 - rau.163 rau:MC5_01035 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.129182 Alphaproteobacteria.159259 Rickettsia.2335 - rmc.426 rmc:RMONA_02735 hsdM; Type I restriction enzyme EcoKI M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.338174 Gammaproteobacteria.26148 Acinetobacter.4608 Acinetobacter_baumannii.5150 aby.2524 aby:ABAYE2749 conserved hypothetical protein; putative restriction-modification protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.338174 Gammaproteobacteria.26148 Acinetobacter.4608 Acinetobacter_baumannii.5150 abn.3072 abn:AB57_3253 response regulator OC.187915 Bacteria.185529 Proteobacteria.338174 Gammaproteobacteria.26148 Acinetobacter.4608 Acinetobacter_baumannii.5150 abaj.3006 abaj:BJAB0868_03048 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.338174 Gammaproteobacteria.26148 Acinetobacter.4608 Acinetobacter_baumannii.5150 abau.1461 abau:IX87_08470 response regulator; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Proteobacteria.338174 Gammaproteobacteria.26148 Acinetobacter.4608 Acinetobacter_baumannii.5150 abw.668 abw:BL01_03540 response regulator; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Firmicutes.214437 Firmicutes___Bacilli.186574 Staphylococcus.11057 - spet.1583 spet:CEP67_08485 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Tenericutes.16010 Phytoplasma.1093 - - pml.208 pml:ATP_00220 hsdM; Type I restriction-modification system, methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Tenericutes.17959 Spiroplasma.5514 - - skn.592 skn:SKUN_001527 hsdM; Type I restriction enzyme, M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Bacteroidetes.100945 Flavobacterium.11677 - - fbr.811 fbr:FBFL15_0854 Probable type I modification methyltransferase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187915 Bacteria.185529 Bacteroidetes.146338 - - - ise.1097 ise:JBKA6_1415 type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187916 Bacteria.1041866 Proteobacteria.498209 Betaproteobacteria.160690 Burkholderia.68073 Burkholderia_sp_.42616 buq.187 buq:AC233_00930 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187917 Bacteria.849898 Firmicutes.212425 Firmicutes___Bacilli.184455 Staphylococcus.7950 Staphylococcus_aureus.5137 sauc.2464 sauc:CA347_78 N-6 DNA Methylase family protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187918 Bacteria.1117402 Proteobacteria.631112 Epsilonproteobacteria.17106 Helicobacter.6092 Helicobacter_cetorum.2445 hcm.1434 hcm:HCD_07765 hypothetical protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187919 Bacteria.185638 Proteobacteria.129633 Alphaproteobacteria.159727 Rickettsia.2993 - rfe.27 rfe:RF_p07 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187919 Bacteria.185638 Proteobacteria.129633 Alphaproteobacteria.159727 Rickettsia.2993 - rfe.27 rfe:RF_pd07 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187920 Archaea.76954 Euryarchaeota.62300 Thermococcus.9025 Thermococcus_sp_.7138 - thv.1287 thv:ADU37_CDS12880 Type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187921 Archaea.54063 Euryarchaeota.34714 Methanosarcina.8911 Methanosarcina_sp_.6894 - meq.2586 meq:MSWHS_2668 Type I restriction-modification enzyme M subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187921 Archaea.54063 Euryarchaeota.34714 - - - mev.271 mev:Metev_0163 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187922 Archaea.77830 Euryarchaeota.63266 Thermococcus.12281 - - tnu.86 tnu:BD01_0089 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187923 Archaea.69315 Euryarchaeota.54472 Methanosaeta.3318 - - mhi.2014 mhi:Mhar_2144 Putative N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187924 Archaea.69334 Euryarchaeota.54492 Methanosaeta.3348 - - mhi.2076 mhi:Mhar_2209 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187925 Archaea.63670 Euryarchaeota.48625 Methanocaldococcus.1961 - - mfe.522 mfe:Mefer_0543 N-6 DNA methylase; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187926 Archaea.37233 Thaumarchaeota.3088 Nitrososphaera.1927 - - nev.31 nev:NTE_01143 type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187926 Archaea.37233 Thaumarchaeota.3088 Nitrososphaera.1927 - - nev.31 nev:NTE_00285 type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187927 Eukaryotes.485506 Animals.258624 Cnidarians.42290 - - nve.13203 nve:NEMVE_v1g225887 hypothetical protein OC.187928 Archaea.39071 - - - - loki.725 loki:Lokiarch_29660 Type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187928 Archaea.39071 - - - - loki.725 loki:Lokiarch_17730 putative type I restriction enzymeP M protein; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187929 Archaea.91780 Thaumarchaeota.4855 Nitrosopumilus.4112 - - nmr.614 nmr:Nmar_0610 restriction modification system DNA specificity domain; K03427 type I restriction enzyme M protein [EC:2.1.1.72] OC.187930 Archaea.69314 Euryarchaeota.54471 Methanosaeta.3317 - - mhi.2013 mhi:Mhar_2143 N-6 DNA methylase; K01154 type I restriction enzyme, S subunit [EC:3.1.21.3] OC.187931 Archaea.54062 Euryarchaeota.34713 Methanosarcina.8910 Methanosarcina_sp_.6893 - meq.2585 meq:MSWHS_2667 EcoKI restriction-modification system protein HsdS OC.187931 Archaea.54062 Euryarchaeota.34713 - - - mev.270 mev:Metev_0162 DNA methylase-type I restriction-modification system