# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.226731 Bacteria.529534 Proteobacteria.553464 Deltaproteobacteria.20178 - - dao.454 dao:Desac_0397 Radical SAM domain protein; K22227 heme synthase OC.226732 Bacteria.1103104 Proteobacteria.604583 Deltaproteobacteria.117657 - - dti.2736 dti:Desti_2956 putative heme d1 biosynthesis radical SAM protein NirJ2; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 Desulfovibrio_vulgaris.2860 dvu.844 dvu:DVU0855 radical SAM domain-containing protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 Desulfovibrio_vulgaris.2860 dvl.2116 dvl:Dvul_2128 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 Desulfovibrio_vulgaris.2860 dvm.2858 dvm:DvMF_2901 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 Desulfovibrio_vulgaris.2860 dvg.780 dvg:Deval_0785 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 Desulfovibrio_desulfuricans.3723 dds.288 dds:Ddes_0287 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 - dfi.2288 dfi:AXF13_12310 heme b synthase; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 - dpg.1517 dpg:DESPIGER_1625 Radical SAM domain heme biosynthesis protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 - def.2362 def:CNY67_13555 ahbD; heme b synthase; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1585 - dtr.962 dtr:RSDT_0965 ahbD; alternative heme biosynthesis protein AhbD; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1586 - dgg.2364 dgg:DGI_2628 putative radical SAM domain-containing protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.1587 - dde.2182 dde:Dde_2577 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.9734 - dsa.1234 dsa:Desal_1240 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.9734 - dhy.3174 dhy:DESAM_22934 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.13188 Desulfovibrio_desulfuricans.3423 ddn.3421 ddn:DND132_3455 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.16040 - daf.2523 daf:Desaf_2642 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfovibrio.21526 - dma.614 dma:DMR_04480 hypothetical protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Pseudodesulfovibrio.1037 - das.2159 das:Daes_2206 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Pseudodesulfovibrio.1037 - dpi.3298 dpi:BN4_20515 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Pseudodesulfovibrio.1037 - dej.2754 dej:AWY79_14415 heme b synthase; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Pseudodesulfovibrio.1037 - pprf.3689 pprf:DPRO_4012 albA; Antilisterial bacteriocin subtilosin biosynthesis protein AlbA; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Lawsonia.408 - lip.205 lip:LI0206 predicted Fe-S oxidoreductases; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Lawsonia.408 - lir.208 lir:LAW_00209 radical SAM domain-containing protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfomicrobium.543 - dba.2297 dba:Dbac_2393 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfomicrobium.543 - doa.865 doa:AXF15_04760 heme b synthase; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 - - drt.1901 drt:Dret_1955 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfococcus.1754 - dml.1248 dml:Dmul_12470 pqqE; PqqE: predicted coenzyme PQQ synthesis protein E; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 Desulfococcus.4775 - dol.1246 dol:Dole_1223 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 - - dal.3661 dal:Dalk_3856 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 - - dat.2712 dat:HRM2_28000 ppqE2; PpqE2; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 - - dto.2110 dto:TOL2_C22120 ppqE; PqqE: predicted coenzyme PQQ synthesis protein E; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 - - sfu.2901 sfu:Sfum_3058 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.265160 Deltaproteobacteria.20176 - - dbr.826 dbr:Deba_0779 Radical SAM domain protein; K22227 heme synthase OC.226734 Bacteria.529533 Proteobacteria.553463 Deltaproteobacteria.20177 - - sat.2061 sat:SYN_02266 radical SAM superfamily protein; K22227 heme synthase OC.226738 Bacteria.1079850 Proteobacteria.554106 Deltaproteobacteria.23227 - - dat.2710 dat:HRM2_27980 ppqE1; PpqE1; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 Desulfovibrio_vulgaris.2862 dvu.846 dvu:DVU0857 12,18-didecarboxysiroheme deacetylase; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 Desulfovibrio_vulgaris.2862 dvl.2114 dvl:Dvul_2126 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 Desulfovibrio_vulgaris.2862 dvm.2860 dvm:DvMF_2903 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 Desulfovibrio_vulgaris.2862 dvg.782 dvg:Deval_0787 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - dde.2180 dde:Dde_2575 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 Desulfovibrio_desulfuricans.3725 dds.290 dds:Ddes_0289 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - dsa.1236 dsa:Desal_1242 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - dhy.3172 dhy:DESAM_22932 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - dfi.2290 dfi:AXF13_12320 12,18-didecarboxysiroheme deacetylase; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - dpg.1514 dpg:DESPIGER_1622 Radical SAM domain heme biosynthesis protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - def.2360 def:CNY67_13545 ahbC; 12,18-didecarboxysiroheme deacetylase; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1589 - dtr.964 dtr:RSDT_0967 ahbC; alternative heme biosynthesis protein AhbC; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1590 - dgg.2366 dgg:DGI_2630 putative radical SAM protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1591 - dma.609 dma:DMR_04410 hypothetical protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.1592 - daf.2527 daf:Desaf_2646 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfovibrio.13190 Desulfovibrio_desulfuricans.3425 ddn.3423 ddn:DND132_3457 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Pseudodesulfovibrio.1035 - das.2157 das:Daes_2204 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Pseudodesulfovibrio.1035 - dpi.3300 dpi:BN4_20517 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Pseudodesulfovibrio.1035 - dej.2752 dej:AWY79_14405 12,18-didecarboxysiroheme deacetylase; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Pseudodesulfovibrio.1035 - pprf.3691 pprf:DPRO_4014 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Lawsonia.406 - lip.203 lip:LI0204 predicted Fe-S oxidoreductases; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Lawsonia.406 - lir.206 lir:LAW_00207 radical SAM domain-containing protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfomicrobium.541 - dba.2295 dba:Dbac_2391 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 Desulfomicrobium.541 - doa.1124 doa:AXF15_06225 12,18-didecarboxysiroheme deacetylase; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 - - drt.1899 drt:Dret_1953 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226740 Bacteria.529846 Proteobacteria.266816 Deltaproteobacteria.23223 - - dto.2108 dto:TOL2_C22100 radical SAM domain protein, related to coenzyme PQQ biosynthesis protein E; K22226 Fe-coproporphyrin III synthase OC.226741 Bacteria.939742 Proteobacteria.266818 Deltaproteobacteria.23228 - - sat.2063 sat:SYN_02268 radical SAM superfamily protein; K22226 Fe-coproporphyrin III synthase OC.226741 Bacteria.939742 Proteobacteria.266818 Deltaproteobacteria.23230 - - dbr.2834 dbr:Deba_2955 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226742 Bacteria.529847 Proteobacteria.266817 Deltaproteobacteria.23224 - - dal.3663 dal:Dalk_3858 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226742 Bacteria.529847 Proteobacteria.266817 Deltaproteobacteria.23225 Desulfococcus.91 - dol.1248 dol:Dole_1225 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226742 Bacteria.529847 Proteobacteria.266817 Deltaproteobacteria.23225 Desulfococcus.91 - dml.1250 dml:Dmul_12490 radical SAM domain protein, related to coenzyme PQQ biosynthesis protein E; K22226 Fe-coproporphyrin III synthase OC.226742 Bacteria.529847 Proteobacteria.266817 Deltaproteobacteria.23226 - - dao.129 dao:Desac_0013 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226742 Bacteria.529847 Proteobacteria.266817 Deltaproteobacteria.23229 - - sfu.2899 sfu:Sfum_3056 Radical SAM domain protein; K22226 Fe-coproporphyrin III synthase OC.226743 Bacteria.571870 Proteobacteria.604407 Deltaproteobacteria.117459 - - dti.2421 dti:Desti_2579 putative heme d1 biosynthesis radical SAM protein NirJ1; K22226 Fe-coproporphyrin III synthase OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 Geobacter_sulfurreducens.1791 gsu.2736 gsu:GSU2905 radical SAM domain-containing iron-sulfur cluster-binding oxidoreductase OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 Geobacter_sulfurreducens.1791 gsk.2664 gsk:KN400_2846 radical SAM domain iron-sulfur cluster-binding oxidoreductase OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 - gme.572 gme:Gmet_0566 radical SAM domain iron-sulfur cluster-binding oxidoreductase OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 - gur.1722 gur:Gura_1767 Radical SAM domain protein OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 - geo.3245 geo:Geob_3352 radical SAM domain iron-sulfur cluster-binding oxidoreductase OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 - gpi.558 gpi:GPICK_03015 radical SAM protein OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Geobacter.5271 - gao.2220 gao:A2G06_13685 radical SAM/SPASM domain-containing protein OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 - - gsb.1107 gsb:GSUB_06410 radical SAM protein OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Desulfuromonas.309 - des.1555 des:DSOUD_1578 GeoRSP system radical SAM/SPASM protein OC.226747 Bacteria.531146 Proteobacteria.271457 Deltaproteobacteria.31506 Desulfuromonas.309 - deu.1912 deu:DBW_2060 radical SAM domain-containing iron-sulfur cluster-binding oxidoreductase