# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.3056 Bacteria.6753 Proteobacteria.278373 Deltaproteobacteria.42584 Pelobacter.1259 - pca.222 pca:Pcar_0181 sensor histidine kinase response regulator, PAS and PAS domain-containing, putative heme-binding site OC.3056 Bacteria.6753 Proteobacteria.278373 Deltaproteobacteria.42584 Pelobacter.1259 - pace.2603 pace:A6070_14185 hypothetical protein OC.3056 Bacteria.6753 Proteobacteria.278373 Deltaproteobacteria.42584 - - sfu.2952 sfu:Sfum_3112 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 Geobacter_sp_.424 gem.2047 gem:GM21_2079 multi-sensor hybrid histidine kinase OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 Geobacter_sp_.424 geb.2048 geb:GM18_2098 multi-sensor hybrid histidine kinase OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 Geobacter_sp_.1804 geb.358 geb:GM18_0309 multi-sensor hybrid histidine kinase OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 Geobacter_sp_.3761 geb.3412 geb:GM18_3541 multi-sensor hybrid histidine kinase OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 Geobacter_sp_.4474 gem.272 gem:GM21_0257 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 - gbm.297 gbm:Gbem_0272 sensor histidine kinase response regulator, Cache_1, HAMP, PAS, PAS and sensory_box domain-containing OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 - gbm.805 gbm:Gbem_0801 sensor histidine kinase response regulator, PAS, PAS, PAS and PAS domain-containing OC.3056 Bacteria.6783 Proteobacteria.5371 Deltaproteobacteria.3378 Geobacter.71 - gbm.2092 gbm:Gbem_2137 sensor histidine kinase, Cache_1, PAS, PAS, PAS and PAS domain-containing OC.3056 Bacteria.6801 Proteobacteria.285003 Deltaproteobacteria.56355 - - samy.1610 samy:DB32_001313 Sensory box histidine kinase/response regulator OC.3056 Bacteria.6801 Proteobacteria.285005 Deltaproteobacteria.56357 - - mrm.2987 mrm:A7982_02596 sensory box histidine kinase/response regulator OC.3056 Bacteria.6869 Proteobacteria.611418 Deltaproteobacteria.126515 - - llu.4107 llu:AKJ09_04226 sensory box histidine kinase/response regulator OC.3056 Bacteria.6966 Proteobacteria.791004 Gammaproteobacteria.457066 - - tee.1812 tee:Tel_09320 hypothetical protein OC.3056 Bacteria.7037 Proteobacteria.618700 Deltaproteobacteria.135222 - - samy.750 samy:DB32_000281 sensory box histidine kinase/response regulator OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Geobacter.64 Geobacter_sulfurreducens.388 gsu.1366 gsu:GSU1443 sensor histidine kinase response regulator, HAMP domain-containing OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Geobacter.64 Geobacter_sulfurreducens.388 gsk.1356 gsk:KN400_1470 sensor histidine kinase response regulator, HAMP domain-containing OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Geobacter.64 - gme.1219 gme:Gmet_1243 sensor histidine kinase response regulator, HAMP domain-containing OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Geobacter.64 - gur.2331 gur:Gura_2428 integral membrane sensor hybrid histidine kinase OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Geobacter.64 - gpi.1073 gpi:GPICK_05970 histidine kinase OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Geobacter.64 - gao.1586 gao:A2G06_09785 hybrid sensor histidine kinase/response regulator OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Pelobacter.5062 - ppd.74 ppd:Ppro_1138 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7073 Proteobacteria.177994 Deltaproteobacteria.3392 Pelobacter.5062 - ppd.74 ppd:Ppro_1139 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7105 Proteobacteria.595437 Deltaproteobacteria.105698 - - dal.1702 dal:Dalk_1600 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7121 Proteobacteria.575165 Deltaproteobacteria.77857 Geobacter.7497 Geobacter_sp_.4016 geb.3841 geb:GM18_4003 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7148 Proteobacteria.177992 Deltaproteobacteria.3394 - - dak.1476 dak:DaAHT2_1508 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7148 Proteobacteria.177992 Deltaproteobacteria.3395 Desulfobulbus.3321 - dpr.1610 dpr:Despr_1690 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7148 Proteobacteria.177992 Deltaproteobacteria.3400 Geobacter.7215 Geobacter_sp_.3283 geb.2746 geb:GM18_2831 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7176 Proteobacteria.559352 Deltaproteobacteria.52826 - - dal.3249 dal:Dalk_3402 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7176 Proteobacteria.559352 Deltaproteobacteria.52826 - - dbr.2212 dbr:Deba_2255 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7177 Proteobacteria.566803 Deltaproteobacteria.65147 Desulfococcus.6234 - dol.3135 dol:Dole_3263 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3446 - - dak.663 dak:DaAHT2_0648 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.1837 Geobacter_sp_.2326 geb.1232 geb:GM18_1245 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.1837 Geobacter_sp_.6052 gem.2832 gem:GM21_2898 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.1837 - glo.94 glo:Glov_1828 multi-sensor signal transduction histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.1837 - glo.94 glo:Glov_1718 multi-sensor signal transduction histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.1837 - gbm.1364 gbm:Gbem_1383 sensor histidine kinase response regulator, CHASE and PAS domain-containing OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.2287 Geobacter_sp_.2808 geb.1958 geb:GM18_2002 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.2287 Geobacter_sp_.5447 gem.1970 gem:GM21_2001 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.2287 - gbm.2177 gbm:Gbem_2226 sensor histidine kinase response regulator, PAS and PAS domain-containing OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.3759 Geobacter_sp_.4578 gem.460 gem:GM21_0452 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7239 Proteobacteria.4126 Deltaproteobacteria.3448 Geobacter.3759 - gbm.444 gbm:Gbem_0429 sensor histidine kinase response regulator, Cache_1, PAS and PAS domain-containing OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.4 dbr:Deba_2688 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.4 dbr:Deba_3053 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.4 dbr:Deba_1323 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.4 dbr:Deba_0130 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.4 dbr:Deba_0089 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.2211 dbr:Deba_2254 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7347 Proteobacteria.272958 Deltaproteobacteria.3407 - - dbr.2703 dbr:Deba_2817 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7374 Proteobacteria.551542 Deltaproteobacteria.3404 - - sfu.1390 sfu:Sfum_1337 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7378 Proteobacteria.594872 Deltaproteobacteria.104890 - - dak.2053 dak:DaAHT2_2152 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7432 Proteobacteria.280728 Deltaproteobacteria.46166 Sorangium.5215 - scl.777 scl:sce0589 two-component hybrid sensor and regulator OC.3056 Bacteria.7432 Proteobacteria.280728 Deltaproteobacteria.46166 Sorangium.5215 - scu.1042 scu:SCE1572_04075 hypothetical protein OC.3056 Bacteria.7432 Proteobacteria.280728 Deltaproteobacteria.46166 - - ccro.5278 ccro:CMC5_056190 uncharacterized protein OC.3056 Bacteria.7455 Proteobacteria.4316 Deltaproteobacteria.3409 Anaeromyxobacter.5470 Anaeromyxobacter_sp_.3216 afw.2956 afw:Anae109_3017 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7455 Proteobacteria.4316 Deltaproteobacteria.3412 Geobacter.6070 - gur.347 gur:Gura_0269 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7455 Proteobacteria.4316 Deltaproteobacteria.3412 Geobacter.6070 - geo.1142 geo:Geob_1173 sensor histidine kinase response regulator, HAMP and PAS domain-containing OC.3056 Bacteria.7455 Proteobacteria.4316 Alphaproteobacteria.191592 Bradyrhizobium.13634 Bradyrhizobium_japonicum.1424 bju.2443 bju:BJ6T_24350 hypothetical protein OC.3056 Bacteria.7455 Proteobacteria.4316 Alphaproteobacteria.191592 Bradyrhizobium.13634 Bradyrhizobium_japonicum.1424 bjp.2311 bjp:RN69_11885 histidine kinase OC.3056 Bacteria.7468 Proteobacteria.602128 Deltaproteobacteria.114355 - - drt.128 drt:Dret_0082 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7470 Proteobacteria.608497 Deltaproteobacteria.122800 - - hoh.2279 hoh:Hoch_2685 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7474 Proteobacteria.796391 Gammaproteobacteria.467017 - - woc.599 woc:BA177_02910 hypothetical protein OC.3056 Bacteria.7512 Proteobacteria.272937 Deltaproteobacteria.3403 - - dti.170 dti:Desti_1947 PAS domain S-box OC.3056 Bacteria.7512 Proteobacteria.272937 Deltaproteobacteria.3403 - - dti.171 dti:Desti_1309 PAS domain S-box OC.3056 Bacteria.7512 Proteobacteria.272937 Deltaproteobacteria.3403 - - dti.173 dti:Desti_3510 PAS domain S-box OC.3056 Bacteria.7512 Proteobacteria.272937 Deltaproteobacteria.3403 - - dti.174 dti:Desti_4201 PAS domain S-box OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 Geobacter_sp_.277 gem.1782 gem:GM21_1812 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 Geobacter_sp_.277 geb.1728 geb:GM18_1762 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 Geobacter_sulfurreducens.609 gsu.1573 gsu:GSU1655 response receiver sensor histidine kinase response regulator, PAS and GAF domain-containing OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 Geobacter_sulfurreducens.609 gsk.1556 gsk:KN400_1677 response receiver sensor histidine kinase response regulator, PAS and GAF domain-containing OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 - gme.1868 gme:Gmet_1918 response receiver sensor histidine kinase response regulator, PAS domain-containing OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 - gur.2282 gur:Gura_2373 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 - gbm.2354 gbm:Gbem_2406 response receiver sensor histidine kinase response regulator, PAS and PAS domain-containing OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 - geo.2689 geo:Geob_2770 response receiver sensor histidine kinase response regulator, PAS domain-containing OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 - gpi.1306 gpi:GPICK_07375 histidine kinase OC.3056 Bacteria.7546 Proteobacteria.5375 Deltaproteobacteria.3375 Geobacter.2237 - gao.1418 gao:A2G06_08750 hybrid sensor histidine kinase/response regulator OC.3056 Bacteria.7652 Proteobacteria.770535 Gammaproteobacteria.413187 - - gai.3487 gai:IMCC3135_18405 Blue-light-activated protein OC.3056 Bacteria.7736 Proteobacteria.581276 Deltaproteobacteria.86784 Pelobacter.6135 - ppd.1186 ppd:Ppro_1171 histidine kinase OC.3056 Bacteria.7737 Proteobacteria.583081 Deltaproteobacteria.89440 Sorangium.2442 - scl.3977 scl:sce3940 sensory box histidine kinase/response regulator hybrid OC.3056 Bacteria.7737 Proteobacteria.583081 Deltaproteobacteria.89440 Sorangium.2442 - scu.4644 scu:SCE1572_23645 hypothetical protein OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3389 Geobacter.67 Geobacter_sp_.4026 geb.3851 geb:GM18_4019 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 Geobacter_sp_.534 gem.1694 gem:GM21_1723 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 Geobacter_sp_.534 geb.2294 geb:GM18_2354 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 Geobacter_sp_.739 gem.1266 gem:GM21_1283 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 Geobacter_sp_.739 geb.2741 geb:GM18_2824 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 Geobacter_sp_.5210 gem.1540 gem:GM21_1566 PAS/PAC sensor hybrid histidine kinase; K02030 polar amino acid transport system substrate-binding protein OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 - gbm.2441 gbm:Gbem_2494 response receiver sensor histidine kinase response regulator, PAS domain-containing OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 - gbm.2613 gbm:Gbem_2669 periplasmic substrate-binding sensor histidine kinase response regulator, PBPb, PAS and Hist_Kin_Sens domain-containing OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.69 - gbm.2874 gbm:Gbem_2939 periplasmic substrate-binding sensor histidine kinase response regulator, PBPb, PAS and Hist_Kin_Sens domain-containing OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.70 Geobacter_sp_.4185 geb.4132 geb:GM18_4310 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.70 Geobacter_sp_.6648 gem.3873 gem:GM21_3966 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.70 - gbm.3777 gbm:Gbem_3878 sensor histidine kinase response regulator, PAS and PAS domain-containing OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.72 Geobacter_sp_.2965 geb.2211 geb:GM18_2270 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.72 Geobacter_sp_.5602 gem.2228 gem:GM21_2264 multi-sensor hybrid histidine kinase OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.72 - gbm.1909 gbm:Gbem_1952 response receiver histidine kinase response regulator OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.72 - geo.1802 geo:Geob_1847 response receiver sensor histidine kinase response regulator, PAS domain-containing OC.3056 Bacteria.7958 Proteobacteria.177993 Deltaproteobacteria.3391 Geobacter.74 - gao.2049 gao:A2G06_12580 hypothetical protein OC.3056 Bacteria.8027 Proteobacteria.257471 Deltaproteobacteria.10790 Anaeromyxobacter.909 Anaeromyxobacter_sp_.4277 afw.4236 afw:Anae109_4372 signal transduction histidine kinase, nitrogen specific, NtrB OC.3056 Bacteria.8027 Proteobacteria.257471 Deltaproteobacteria.10790 Anaeromyxobacter.909 Anaeromyxobacter_sp_.7793 ank.4295 ank:AnaeK_4355 signal transduction histidine kinase, nitrogen specific, NtrB OC.3056 Bacteria.8027 Proteobacteria.257471 Deltaproteobacteria.10790 Anaeromyxobacter.909 Anaeromyxobacter_dehalogenans.1837 ade.4199 ade:Adeh_4222 signal transduction histidine kinase, nitrogen specific, NtrB OC.3056 Bacteria.8027 Proteobacteria.257471 Deltaproteobacteria.10790 Anaeromyxobacter.909 Anaeromyxobacter_dehalogenans.1837 acp.4308 acp:A2cp1_4378 signal transduction histidine kinase, nitrogen specific, NtrB OC.3056 Bacteria.8075 Proteobacteria.595238 Deltaproteobacteria.105435 - - dal.1071 dal:Dalk_0895 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.8239 Proteobacteria.602254 Deltaproteobacteria.114536 - - drt.922 drt:Dret_0930 PAS/PAC sensor hybrid histidine kinase OC.3056 Bacteria.8426 Proteobacteria.583061 Deltaproteobacteria.89415 Sorangium.2150 - scl.3638 scl:sce3598 unnamed protein product; Family membership OC.3056 Bacteria.8426 Proteobacteria.583061 Deltaproteobacteria.89415 Sorangium.2150 - scu.4290 scu:SCE1572_21780 hypothetical protein OC.3056 Bacteria.8510 Proteobacteria.4589 Alphaproteobacteria.219868 Labrenzia.6040 Labrenzia_sp_.4369 labr.3603 labr:CHH27_18730 hypothetical protein OC.3056 Bacteria.8510 Proteobacteria.466091 Alphaproteobacteria.328069 - - ncb.1179 ncb:C0V82_05615 hypothetical protein OC.3057 Bacteria.7070 Proteobacteria.472151 Alphaproteobacteria.338605 - - rbm.1993 rbm:TEF_10130 hypothetical protein