# OC Root 2nd 3rd 4th 5th PC Gene/Definition OC.336199 Archaea.8374 Crenarchaeota.1557 Ignicoccus.343 - iho.1353 iho:Igni_1367 nickel-dependent hydrogenase, large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Ignicoccus.343 - iis.72 iis:EYM_00290 cytochrome B; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 - - hbu.1308 hbu:Hbut_1368 Periplasmic hydrogenase large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 - - pfm.113 pfm:Pyrfu_0078 nickel-dependent hydrogenase large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 - - pdl.652 pdl:Pyrde_0647 Ni,Fe-hydrogenase I large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Sulfolobus.4420 Sulfolobus_islandicus.4077 sih.871 sih:SiH_0892 [NiFe] hydrogenase large subunit, HyaB; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Sulfolobus.4420 - sula.113 sula:BFU36_00485 cytochrome C; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Acidianus.1718 - aman.832 aman:B6F84_04120 hypothetical protein; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Acidianus.1718 - abri.707 abri:DFR85_03785 cytochrome B; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Acidianus.1718 - asul.778 asul:DFR86_04020 cytochrome B; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Pyrobaculum.2507 - pis.220 pis:Pisl_0197 nickel-dependent hydrogenase, large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Pyrobaculum.2507 - pcl.1525 pcl:Pcal_1578 nickel-dependent hydrogenase, large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Pyrobaculum.2507 - pas.1238 pas:Pars_1298 nickel-dependent hydrogenase, large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Pyrobaculum.2507 - pog.914 pog:Pogu_0917 Ni,Fe-hydrogenase I large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Pyrobaculum.2507 - tne.409 tne:Tneu_0407 nickel-dependent hydrogenase large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Thermoproteus.966 - tuz.2143 tuz:TUZN_2207 Ni,Fe-hydrogenase I large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Thermoproteus.966 - ttn.49 ttn:TTX_0033 hynL; Ni,Fe-hydrogenase I large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Vulcanisaeta.2357 - vdi.2227 vdi:Vdis_2308 nickel-dependent hydrogenase large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Thermofilum.880 - tpe.576 tpe:Tpen_0592 nickel-dependent hydrogenase, large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Thermofilum.880 - thb.827 thb:N186_04330 cytochrome B; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Thermofilum.880 - tcb.1844 tcb:TCARB_1894 NiFe hydrogenase, large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] OC.336199 Archaea.8374 Crenarchaeota.1557 Thermofilum.880 - thf.1139 thf:MA03_06640 cytochrome B; K06281 hydrogenase large subunit [EC:1.12.99.6]