# OC Root 2nd 3rd 4th 5th PC Gene/Definition OC.337397 Bacteria.286869 Actinobacteria.75847 Nocardia.8478 - nsr.16 nsr:NS506_00018 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Nocardia.8478 - nsr.16 nsr:NS506_07863 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Nocardia.8478 - ntp.6745 ntp:CRH09_36490 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.149339 Streptomyces.54157 - sco.2735 sco:SCO2687 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - sma.3567 sma:SAVERM_4121 ribA3; putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - sma.5017 sma:SAVERM_545 ribA4; putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - scb.4127 scb:SCAB_49001 putative GTP cyclohydrolase protein; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 Streptomyces_hygroscopicus.4081 shy.4913 shy:SHJG_4976 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 Streptomyces_hygroscopicus.4081 sho.4723 sho:SHJGH_4739 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - sdv.4683 sdv:BN159_4727 ribA3; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.149339 Streptomyces.54157 - sfi.1206 sfi:SFUL_2084 GTP cyclohydrolase-2; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - sci.3623 sci:B446_18275 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.70635 Streptomyces_albulus.6769 salu.7662 salu:DC74_8030 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.70635 Streptomyces_albulus.6769 sall.7851 sall:SAZ_41455 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.149339 Streptomyces.54157 - slv.4735 slv:SLIV_24230 ribA2; GTP cyclohydrolase-2; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.149339 Streptomyces.54157 Streptomyces_sp_.18391 scz.4882 scz:ABE83_25510 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 Streptomyces_sp_.10311 scx.4587 scx:AS200_24475 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - srw.3594 srw:TUE45_03626 ribA; GTP cyclohydrolase-2; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75852 Streptomyces.83654 Streptomyces_sp_.49287 strf.5939 strf:ASR50_31180 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - sgs.8655 sgs:AVL59_45835 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 Streptomyces_sp_.75743 stsi.3658 stsi:A4E84_18990 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - sls.4037 sls:SLINC_4033 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - splu.3168 splu:LK06_017190 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75848 Streptomyces.62469 - sauo.2803 sauo:BV401_15075 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Streptomyces.46261 - spun.4192 spun:BFF78_22470 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75848 Streptomyces.62469 - smal.2342 smal:SMALA_2336 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75848 Streptomyces.62469 - salj.1740 salj:SMD11_1722 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75849 Kitasatospora.19120 - ksk.5732 ksk:KSE_59160 ribA3; putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Kitasatospora.19412 - ksk.6250 ksk:KSE_64690 ribA2; putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Kitasatospora.10939 - kau.222 kau:B6264_00745 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Kitasatospora.15966 - kit.6013 kit:CFP65_6470 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.5251 - mts.1563 mts:MTES_1564 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.1928 Microbacterium_sp_.2452 mim.2302 mim:AKG07_12140 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.1928 Microbacterium_sp_.2452 mix.399 mix:AB663_000732 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.1928 Microbacterium_sp_.2452 mip.1142 mip:AXH82_05955 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.5251 - mcw.280 mcw:A8L33_01360 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.1928 Microbacterium_sp_.2452 micr.3274 micr:BMW26_16855 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Microbacterium.5251 - mhos.532 mhos:CXR34_02740 GTP cyclohydrolase II RibA; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Arthrobacter.32244 Arthrobacter_sp_.33927 aru.2786 aru:ASPU41_14810 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Arthrobacter.24387 Arthrobacter_sp_.25181 arn.1904 arn:CGK93_10245 hypothetical protein; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Pseudarthrobacter.3155 - ach.1794 ach:Achl_1773 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Pseudarthrobacter.5061 - apn.310 apn:Asphe3_02380 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Pseudarthrobacter.9907 - psul.3859 psul:AU252_20625 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - satk.3594 satk:SA2016_3735 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - ica.1003 ica:Intca_1032 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - mph.231 mph:MLP_01300 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.215662 Nocardioides.2631 - nca.943 nca:Noca_0866 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Nocardioides.3080 - nca.1682 nca:Noca_1684 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - psim.4307 psim:KR76_26255 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - kra.272 kra:Krad_0125 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.149339 - - sen.2765 sen:SACE_2884 toxB; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.2010 Amycolatopsis_mediterranei.2548 amd.3305 amd:AMED_3340 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.4545 Amycolatopsis_mediterranei.4606 amd.5189 amd:AMED_5256 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.2010 Amycolatopsis_mediterranei.2548 amn.3396 amn:RAM_16985 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.4545 Amycolatopsis_mediterranei.4606 amn.5333 amn:RAM_26775 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.2010 Amycolatopsis_mediterranei.2548 amm.3305 amm:AMES_3302 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.4545 Amycolatopsis_mediterranei.4606 amm.5189 amm:AMES_5193 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.2010 Amycolatopsis_mediterranei.2548 amz.3305 amz:B737_3302 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.4545 Amycolatopsis_mediterranei.4606 amz.5189 amz:B737_5193 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Amycolatopsis.4545 Amycolatopsis_sp_.12133 amyc.4121 amyc:CU254_21320 GTP cyclohydrolase II RibA; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinosynnema.2641 - ami.3869 ami:Amir_3980 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinosynnema.2641 - apre.3775 apre:CNX65_19930 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - kal.1563 kal:KALB_2273 GTP cyclohydrolase-2; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75853 - - kphy.4644 kphy:AOZ06_24650 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Salinispora.1246 - stp.2508 stp:Strop_2559 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Salinispora.1246 - saq.2673 saq:Sare_2747 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Micromonospora.3574 - mau.3556 mau:Micau_3610 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Micromonospora.3574 Micromonospora_sp_.8179 mil.4682 mil:ML5_4788 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Micromonospora.3574 Micromonospora_sp_.4584 micb.2635 micb:MicB006_2667 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - vma.3972 vma:VAB18032_20180 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1031 - ams.475 ams:AMIS_13360 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.3902 - ams.4497 ams:AMIS_50940 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1030 - ams.5523 ams:AMIS_60390 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.3902 Actinoplanes_sp_.2130 ase.2265 ase:ACPL_3070 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1033 Actinoplanes_sp_.5315 ase.6296 ase:ACPL_676 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1031 Actinoplanes_sp_.9732 actn.1873 actn:L083_1829 ribA; GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1029 Actinoplanes_sp_.12066 actn.4388 actn:L083_4404 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1031 - afs.1880 afs:AFR_08995 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1032 - afs.3925 afs:AFR_19715 putative GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.1033 Actinoplanes_sp_.5315 acts.571 acts:ACWT_0560 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Actinoplanes.3902 Actinoplanes_sp_.2130 acts.2486 acts:ACWT_2476 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Plantactinospora.8714 - plk.1815 plk:CIK06_10095 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Plantactinospora.4939 - plab.5801 plab:C6361_30410 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 Plantactinospora.4939 - plat.6832 plat:C6W10_35690 GTP cyclohydrolase; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - cai.2001 cai:Caci_1820 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25] OC.337397 Bacteria.286869 Actinobacteria.75847 - - cai.3823 cai:Caci_3851 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II [EC:3.5.4.25]