# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.338134 Bacteria.396540 Nitrospirae.6942 Nitrospira.3499 - - nde.618 nde:NIDE0565 conserved protein of unknown function, metallo-beta-lactamase superfamily OC.338135 Bacteria.1120472 Proteobacteria.635201 Epsilonproteobacteria.21732 Sulfuricurvum.2813 - sulr.811 sulr:B649_04000 hypothetical protein OC.338136 Bacteria.396538 Proteobacteria.559928 Deltaproteobacteria.53902 - - hmr.737 hmr:Hipma_0757 beta-lactamase domain protein OC.338136 Bacteria.396538 Proteobacteria.559928 Deltaproteobacteria.53902 - - dav.1277 dav:DESACE_06915 beta-lactamase OC.338136 Bacteria.396538 Spirochaetes.11230 Treponema.2725 - - tde.2409 tde:TDE2498 metallo-beta-lactamase OC.338136 Bacteria.396538 Spirochaetes.11230 Treponema.2725 - - tped.2526 tped:TPE_2658 metallo-beta-lactamase OC.338136 Bacteria.396538 Spirochaetes.11230 Treponema.2725 - - scd.52 scd:Spica_0018 beta-lactamase domain protein OC.338136 Bacteria.396538 Spirochaetes.11230 Treponema.2725 - - tpk.186 tpk:JO40_00920 beta-lactamase OC.338136 Bacteria.396538 Spirochaetes.11230 Treponema.2725 - - trm.506 trm:JO41_02715 beta-lactamase OC.338136 Bacteria.396538 Synergistetes.1457 - - - amo.1618 amo:Anamo_1723 putative flavoprotein OC.338136 Bacteria.396538 Synergistetes.1457 - - - sbr.1235 sbr:SY1_21720 Uncharacterized flavoproteins OC.338136 Bacteria.396538 Synergistetes.6370 - - - tai.1632 tai:Taci_1679 beta-lactamase domain-containing protein OC.338136 Bacteria.396538 Aquificae.4859 Hydrogenobaculum.1596 - - hya.395 hya:HY04AAS1_0391 beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_sp_.1562 - trq.922 trq:TRQ2_0932 beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_sp_.1562 - thz.865 thz:CELL2_04725 beta-lactamase domain-containing protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_sp_.2046 - thq.931 thq:T2812B_04715 hypothetical protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_sp_.3304 - thr.937 thr:TRQ7_04900 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_maritima.432 - tma.14 tma:TM0013 hypothetical protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_maritima.432 - tmm.12 tmm:Tmari_0010 hypothetical protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_maritima.432 - tmi.908 tmi:THEMA_04735 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_maritima.432 - tmw.10 tmw:THMA_0009 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_maritima.432 - tmq.10 tmq:THMB_0009 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 Thermotoga_maritima.432 - tmx.9 tmx:THMC_0009 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 - - tpt.900 tpt:Tpet_0910 beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 - - tna.686 tna:CTN_0685 Beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.265 Thermotoga.1289 - - tnp.630 tnp:Tnap_0644 beta-lactamase domain-containing protein OC.338136 Bacteria.396538 Thermotogae.265 Pseudothermotoga.2128 - - phy.1812 phy:AJ81_09470 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Pseudothermotoga.3023 - - tta.1486 tta:Theth_1584 beta-lactamase domain-containing protein OC.338136 Bacteria.396538 Thermotogae.265 Thermosipho.1369 Thermosipho_sp_.818 - thp.180 thp:BG95_00885 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermosipho.1369 Thermosipho_sp_.818 - ther.182 ther:Y592_00890 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.265 Thermosipho.1369 - - tme.1806 tme:Tmel_1868 beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.265 Thermosipho.1369 - - taf.689 taf:THA_163 metallo-beta-lactamase family protein OC.338136 Bacteria.396538 Thermotogae.265 Fervidobacterium.1159 - - fno.349 fno:Fnod_0356 beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.265 Fervidobacterium.1159 - - fpe.423 fpe:Ferpe_0432 putative flavoprotein OC.338136 Bacteria.396538 Thermotogae.265 Fervidobacterium.1159 - - fia.450 fia:NA23_02450 MBL fold metallo-hydrolase OC.338136 Bacteria.396538 Thermotogae.266 - - - pmo.685 pmo:Pmob_0700 beta-lactamase domain protein OC.338136 Bacteria.396538 Thermotogae.267 Marinitoga.1321 - - mpz.622 mpz:Marpi_0632 putative flavoprotein OC.338136 Bacteria.396538 Thermotogae.267 Marinitoga.1321 - - marn.613 marn:LN42_03610 beta-lactamase OC.338136 Bacteria.396538 Thermotogae.267 - - - dtn.541 dtn:DTL3_0538 beta-lactamase domain-containing protein OC.338136 Bacteria.396538 Nitrospirae.11908 - - - tye.238 tye:THEYE_A0175 metallo-beta-lactamase family protein OC.338136 Bacteria.396538 Thermodesulfobacteria.1483 Thermodesulfobacterium.1132 - - tcm.468 tcm:HL41_02820 beta-lactamase OC.338137 Bacteria.396539 Aquificae.4844 Hydrogenobaculum.1459 - - hho.914 hho:HydHO_0941 metallo-beta-lactamase family protein OC.338137 Bacteria.396539 Aquificae.4844 Hydrogenobaculum.1459 - - hys.913 hys:HydSN_0965 putative flavoprotein OC.338138 Bacteria.396541 Nitrospirae.4515 Leptospirillum.1236 - - lfc.1765 lfc:LFE_1861 metallo-beta-lactamase family protein OC.338138 Bacteria.396541 Nitrospirae.4515 Leptospirillum.1236 Leptospirillum_ferriphilum.2677 - lfp.1513 lfp:Y981_08855 beta-lactamase OC.338139 Bacteria.692879 Aquificae.4045 - - - tam.1542 tam:Theam_1559 beta-lactamase domain protein OC.338139 Bacteria.692879 Aquificae.4045 - - - dte.52 dte:Dester_0040 metallo-beta-lactamase superfamily hydrolase OC.338140 Bacteria.396542 Proteobacteria.246553 Gammaproteobacteria.176675 Methylomonas.1128 - mdh.2080 mdh:AYM39_10870 MBL fold metallo-hydrolase OC.338140 Bacteria.396542 Proteobacteria.246553 Gammaproteobacteria.176675 Methylomonas.1128 - mko.2147 mko:MKLM6_2256 MBL fold metallo-hydrolase OC.338140 Bacteria.396542 Proteobacteria.246553 Gammaproteobacteria.176675 - - mah.1094 mah:MEALZ_1105 Beta-lactamase domain protein OC.338140 Bacteria.396542 Proteobacteria.246553 Gammaproteobacteria.323541 Methylomonas.5268 - mdn.2219 mdn:JT25_011805 MBL fold metallo-hydrolase OC.338140 Bacteria.396542 Proteobacteria.246553 Betaproteobacteria.64358 - - cbab.2364 cbab:SMCB_2383 uncharacterized flavoprotein OC.338140 Bacteria.396542 Proteobacteria.246553 Betaproteobacteria.64358 Methylotenera.2820 - mmb.139 mmb:Mmol_0130 beta-lactamase domain protein OC.338140 Bacteria.396542 Proteobacteria.246553 Betaproteobacteria.64358 - - slt.1053 slt:Slit_1053 beta-lactamase domain protein OC.338140 Bacteria.396542 Proteobacteria.246553 Betaproteobacteria.64358 Azoarcus.2922 Azoarcus_sp_.12926 azo.3512 azo:azo3526 conserved hypothetical flavoprotein OC.338140 Bacteria.396542 Proteobacteria.246553 Betaproteobacteria.64358 Azoarcus.2922 - aoa.3591 aoa:dqs_3669 flavoprotein OC.338140 Bacteria.396542 Proteobacteria.246553 Other_proteobacteria.9075 - - htl.909 htl:HPTL_0911 hypothetical flavoprotein OC.338140 Bacteria.396542 Aquificae.2325 Hydrogenobaculum.1020 - - hho.510 hho:HydHO_0522 beta-lactamase domain protein OC.338140 Bacteria.396542 Aquificae.2325 Hydrogenobaculum.1020 - - hys.502 hys:HydSN_0532 putative flavoprotein OC.338140 Bacteria.396542 Aquificae.2325 - - - pmx.217 pmx:PERMA_0189 beta-lactamase domain protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_vulnificus.1604 vvu.1334 vvu:VV1_1506 Uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_vulnificus.1604 vvy.2837 vvy:VV2889 uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_vulnificus.1604 vvm.849 vvm:VVM_00813 - OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_vulnificus.1604 vvl.2520 vvl:VV93_v1c25950 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 - vni.1489 vni:VIBNI_A1587 putative Metallo-hydrolase/oxidoreductase OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_anguillarum.2251 van.1235 van:VAA_01347 Flavodoxin OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_anguillarum.2251 lag.3085 lag:N175_16615 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 Vibrio_anguillarum.2251 vau.3532 vau:VANGNB10_cII0954 Putative metallo-beta-lactamase family protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 - vtu.336 vtu:IX91_01645 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Vibrio.2791 - vta.695 vta:A0580 putative Metallo-hydrolase/oxidoreductase OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - gho.3378 gho:AL542_18085 MBL fold metallo-hydrolase OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - saz.1449 saz:Sama_1458 uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - slo.1736 slo:Shew_1741 beta-lactamase domain protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - sse.2720 sse:Ssed_2746 beta-lactamase domain protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - swd.1884 swd:Swoo_1892 beta-lactamase domain protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - svo.2671 svo:SVI_2679 metallo-beta-lactamase family protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - spsw.1513 spsw:Sps_01562 metallo-beta-lactamase superfamily enzyme OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - smav.2036 smav:CFF01_10660 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Shewanella.7504 - salg.3538 salg:BS332_20750 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Pseudoalteromonas.8867 - pseo.767 pseo:OM33_04120 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Pseudoalteromonas.8867 - pphe.2693 pphe:PP2015_3467 CDP-abequose synthase OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Pseudoalteromonas.8867 - plz.4597 plz:S4054249_24600 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Pseudoalteromonas.8867 - pspo.181 pspo:PSPO_a0195 hypothetical protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Pseudoalteromonas.8867 - ptu.3382 ptu:PTUN_a4033 hypothetical protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - cate.1754 cate:C2869_09505 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - ttu.1633 ttu:TERTU_1838 metallo-beta-lactamase family protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Methylomonas.3618 - mmt.1453 mmt:Metme_1500 metallo-beta-lactamase family protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Methylomonas.3618 - mdn.2666 mdn:JT25_014265 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Methylomonas.3618 - mdh.774 mdh:AYM39_03730 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Methylomonas.3618 - mko.778 mko:MKLM6_0780 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - mah.2716 mah:MEALZ_2882 Metallo-beta-lactamase family protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - hch.582 hch:HCH_00452 uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Thalassolituus.1524 - tol.2613 tol:TOL_2701 metallo-beta-lactamase family protein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 Thalassolituus.1524 - tor.805 tor:R615_04120 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - oai.3096 oai:OLEAN_C31400 Uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - bsan.3044 bsan:CHH28_16090 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Gammaproteobacteria.178055 - - ome.4049 ome:OLMES_4284 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Betaproteobacteria.106393 Janthinobacterium.8655 Janthinobacterium_sp_.6880 jab.3418 jab:VN23_18190 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Betaproteobacteria.106393 - - dsu.1611 dsu:Dsui_1639 putative flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Betaproteobacteria.106393 Dechloromonas.70 - dar.1068 dar:Daro_0995 Beta-lactamase-like protein OC.338141 Bacteria.396543 Proteobacteria.97915 Betaproteobacteria.106393 Dechloromonas.70 - dey.2070 dey:HYN24_11030 MBL fold metallo-hydrolase OC.338141 Bacteria.396543 Proteobacteria.97915 Betaproteobacteria.224254 Thiomonas.342 - tin.1180 tin:Tint_1174 beta-lactamase-like protein OC.338141 Bacteria.396543 Proteobacteria.97915 Betaproteobacteria.224254 Thiomonas.342 - thi.1370 thi:THI_1503 putative beta-lactamase-like OC.338141 Bacteria.396543 Proteobacteria.97915 Alphaproteobacteria.135317 Magnetospirillum.2340 Magnetospirillum_sp_.3208 magx.633 magx:XM1_0384 conserved protein of unknown function OC.338141 Bacteria.396543 Proteobacteria.97915 Alphaproteobacteria.135317 Magnetospirillum.2340 Magnetospirillum_sp_.3208 magn.851 magn:WV31_04320 flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Alphaproteobacteria.135317 Magnetospirillum.2340 - mag.4094 mag:amb4236 Uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Other_proteobacteria.725 Acidithiobacillus.1730 Acidithiobacillus_caldus.816 acu.20 acu:Atc_0197 uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Other_proteobacteria.725 Acidithiobacillus.1730 Acidithiobacillus_caldus.816 acu.20 acu:Atc_1447 uncharacterized flavoprotein OC.338141 Bacteria.396543 Proteobacteria.97915 Other_proteobacteria.725 Acidithiobacillus.1730 Acidithiobacillus_caldus.816 acz.1249 acz:Acaty_c1218 CDP-abequose synthase OC.338141 Bacteria.396543 Spirochaetes.17596 Leptospira.6884 - - laj.3826 laj:A0128_19800 flavoprotein